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Research ArticleClinical Studies

Pre-pectoral Immediate Breast Reconstruction Following Conservative Mastectomy Using Acellular Dermal Matrix and Semi-smooth Implants

UMAR WAZIR, NEILL PATANI, JENNIFER HEENEY, KINAN MOKBEL and KEFAH MOKBEL
Anticancer Research February 2022, 42 (2) 1013-1018; DOI: https://doi.org/10.21873/anticanres.15562
UMAR WAZIR
The London Breast Institute, Princess Grace Hospital, London, U.K.
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NEILL PATANI
The London Breast Institute, Princess Grace Hospital, London, U.K.
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JENNIFER HEENEY
The London Breast Institute, Princess Grace Hospital, London, U.K.
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KINAN MOKBEL
The London Breast Institute, Princess Grace Hospital, London, U.K.
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KEFAH MOKBEL
The London Breast Institute, Princess Grace Hospital, London, U.K.
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  • For correspondence: kefahmokbel@hotmail.com
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Abstract

Background/Aim: Improvements in acellular dermal matrix (ADM) and surgical techniques have facilitated pre-pectoral immediate breast reconstruction (IBR). Outer shell texturing is a key risk factor for anaplastic large cell lymphoma, prompting this evaluation of reconstruction with nano-textured rounded implants. Patients and Methods: Fifty-one consecutive patients underwent 72 pre-pectoral ADM-assisted (fenestrated SurgiMend™) IBRs using nano-textured implants (Sebbin™). Patients were invited to complete a satisfaction questionnaire, including aesthetic outcome (linear scale 0-10) during follow-up. Results: Average mastectomy weight was 300 g (range=83-1,018 g). After a mean follow-up of 18.3 month, 2 patients (2.8%) had minor wound complications. One patient suffered nipple necrosis. Capsular contracture occurred in 5 cases (6.9%) and significant rippling in one case. No implants were lost. Patient-reported aesthetic outcomes had a mean score of 9.3 (range=3-10; N=71). Conclusion: Pre-pectoral ADM-assisted IBR using semi-smooth implants following NSM is reliable and safe, with a low incidence of complications and high patient satisfaction.

Key Words:
  • Breast reconstruction
  • pre-pectoral
  • semi-smooth implant
  • nano-textured
  • acellular dermal matrix
  • Received December 15, 2021.
  • Revision received January 6, 2022.
  • Accepted January 7, 2022.
  • Copyright © 2022 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.
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Anticancer Research: 42 (2)
Anticancer Research
Vol. 42, Issue 2
February 2022
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Pre-pectoral Immediate Breast Reconstruction Following Conservative Mastectomy Using Acellular Dermal Matrix and Semi-smooth Implants
UMAR WAZIR, NEILL PATANI, JENNIFER HEENEY, KINAN MOKBEL, KEFAH MOKBEL
Anticancer Research Feb 2022, 42 (2) 1013-1018; DOI: 10.21873/anticanres.15562

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Pre-pectoral Immediate Breast Reconstruction Following Conservative Mastectomy Using Acellular Dermal Matrix and Semi-smooth Implants
UMAR WAZIR, NEILL PATANI, JENNIFER HEENEY, KINAN MOKBEL, KEFAH MOKBEL
Anticancer Research Feb 2022, 42 (2) 1013-1018; DOI: 10.21873/anticanres.15562
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Keywords

  • Breast reconstruction
  • pre-pectoral
  • semi-smooth implant
  • nano-textured
  • acellular dermal matrix
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