Anticancer Research: 42 (1)

January 2022; Volume 42,Issue 1

Reviews

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Prospects of Improving Early Ovarian Cancer Diagnosis Using Cervical Cell Swabs
EDYTA BISKUP, REGITZE SOLLING WILS, CLAUS HOGDALL and ESTRID HOGDALL

Anticancer Research January 2022, 42 (1) 1-12; DOI: https://doi.org/10.21873/anticanres.15451
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Current Status of Metastatic Cardiophrenic Lymph Nodes (CPLNs) in Patients With Ovarian Cancer: A Review
MIKLOS ACS, POMPILIU PISO and SONIA PRADER

Anticancer Research January 2022, 42 (1) 13-24; DOI: https://doi.org/10.21873/anticanres.15452
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The Role of Surgery in the Treatment of Metachronous Liver Metastasis from Gastric Cancer: A Systematic Review
PAOLO AURELLO, ANDREA MINERVINI, MARCO PACE, FRANCESCO D’ANGELO, GIUSEPPE NIGRI, LAURA ANTOLINO, STEFANO VALABREGA, GIOVANNI RAMACCIATO and NICCOLÒ PETRUCCIANI

Anticancer Research January 2022, 42 (1) 25-33; DOI: https://doi.org/10.21873/anticanres.15453
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Conversion Surgery for Hepatocellular Carcinoma Following Molecular Therapy
KENSUKE YAMAMURA, TORU BEPPU, TATSUNORI MIYATA, HIROHISA OKABE, HIDETOSHI NITTA, KATSUNORI IMAI, HIROMITSU HAYASHI and SHINICHI AKAHOSHI

Anticancer Research January 2022, 42 (1) 35-44; DOI: https://doi.org/10.21873/anticanres.15454
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Fatigue in Cancer Treatment Studies: Analysis of Placebo Arms
HOLGER HAUCH, BIRTE J. WOLFF and JOHANNES E. WOLFF

Anticancer Research January 2022, 42 (1) 45-52; DOI: https://doi.org/10.21873/anticanres.15455

Clinical Studies

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Adaptive Lumpectomy Boost Planning Can Reduce Normal Tissue Exposure in Patients Receiving Hypofractionated Whole Breast Irradiation
MUTLAY SAYAN, ZEINAB ABOU YEHIA, IMRAAN JAN, APAR GUPTA, IRINA VERGALASOVA, MARC REVIELLO, SHICHA KUMAR, BRUCE HAFFTY and NISHA OHRI

Anticancer Research January 2022, 42 (1) 53-57; DOI: https://doi.org/10.21873/anticanres.15456
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Pre-operative Carboplatin/Paclitaxel Versus 5-Fluorouracil (5-FU)-based Chemoradiotherapy for Older Adults With Esophageal Cancer
MOHAMMED AL-JUMAYLI, KHALIL CHOUCAIR, AMMAR AL-OBAIDI, ROBIN PARK, AJAY BANSAL, JOAQUINA BARANDA, WEIJING SUN and ANWAAR SAEED

Anticancer Research January 2022, 42 (1) 59-66; DOI: https://doi.org/10.21873/anticanres.15457
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Determinative Structural Features Identified With Probe-based Confocal Endomicroscopy for the Accurate Diagnosis of Gallbladder Malignancy
TOMOTAKE KOIZUMI, TAKESHI AOKI, TOSHIKO YAMOCHI, YOSHIHIKO TASHIRO, TATSUYA YAMAZAKI, TOMOKAZU KUSANO, KAZUHIRO MATSUDA, YUSUKE WADA, HIDEKI SHIBATA, KAZUHIKO SAITO, KOJI NOGAKI, TOMOKI HAKOZAKI, KODAI TOMIOKA, TAKAHITO HIRAI, AKIRA FUJIMORI, DOAA A. MANSOUR, AHMED ELEWA ABBAS GAHIN and ROBERT M. HOFFMAN

Anticancer Research January 2022, 42 (1) 67-73; DOI: https://doi.org/10.21873/anticanres.15458
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Survival After Minimally Invasive Surgery in Older Women With Endometrial Carcinoma
JOEL CARDENAS-GOICOECHEA, YU WANG, JI-HYUN LEE, MASSOUD SHORAKA, SEMIRAMIS L. CARBAJAL-MAMANI, DAVID FISHMAN, ANDREA N. RINER and JOSE G. TREVINO

Anticancer Research January 2022, 42 (1) 75-85; DOI: https://doi.org/10.21873/anticanres.15459
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Health-related Quality of Life in Intermediate- or High-risk Patients Treated With Radical External Radiotherapy and Adjuvant Docetaxel for Localized Prostate Cancer: A Randomized, Phase III SPCG-13 Study
MIIKKA LEHTONEN, JORMA SORMUNEN, MARIE HJÄLM-ERIKSSON, CAMILLA THELLENBERG-KARLSSON, TEPPO HUTTUNEN, CLAES GINMAN, PIRKKO-LIISA KELLOKUMPU-LEHTINEN and On Behalf of the Investigators of the Scandinavian Prostate Cancer Group Study No 13

Anticancer Research January 2022, 42 (1) 87-92; DOI: https://doi.org/10.21873/anticanres.15460
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Toxicities and Locoregional Control After External Beam Chest Wall and/or Regional Lymph Node Re-irradiation for Recurrent Breast Cancer
MUTLAY SAYAN, IRINA VERGALASOVA, IMRAAN JAN, SHICHA KUMAR, NANCY CHAN, BRUCE G. HAFFTY and NISHA OHRI

Anticancer Research January 2022, 42 (1) 93-96; DOI: https://doi.org/10.21873/anticanres.15461
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The Benefit of Postoperative Radiotherapy and Extending Neck Dissection in pT1-2 Oral Squamous Cell Carcinoma With a Single Ipsilateral Cervical Lymph Node Metastasis (pN1)
UBAI ALSHARIF, DANIEL STELLER, MOHAMED FALOUGY, LARS THARUN, DIRK RADES and SAMER G. HAKIM

Anticancer Research January 2022, 42 (1) 97-104; DOI: https://doi.org/10.21873/anticanres.15462
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Preoperative Risk Factors for Fibrosarcomatous Transformation in Dermatofibrosarcoma Protuberans
KATHERINE E. MALLETT, SARAH ALMUBARAK, RYAN M. CLAXTON, PETER C. FERGUSON, ANTHONY M. GRIFFIN, PETER S. ROSE, JAY S. WUNDER, KIM TSOI and MATTHEW T. HOUDEK

Anticancer Research January 2022, 42 (1) 105-108; DOI: https://doi.org/10.21873/anticanres.15463
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Prevalence of Diabetes and Impaired Fasting Glycemia in Patients With Oral Cancer: A Retrospective Study in Hungary
ADAM VEGH, DOROTTYA BANYAI, MARTA UJPAL, KATA SARA SOMOGYI, ZITA BICZO, GABOR KAMMERHOFER, ZSOLT NEMETH, PETER HERMANN, MICHAEL PAYER and DANIEL VEGH

Anticancer Research January 2022, 42 (1) 109-113; DOI: https://doi.org/10.21873/anticanres.15464
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Scoring Systems of Peritoneal Dissemination for the Prediction of Operative Completeness in Advanced Ovarian Cancer
SATOSHI HOSOYA, KAZU UEDA, SUGURU ODAJIMA, KOHEI OGAWA, HIROMI KOMAZAKI, TOSHIYUKI SEKI, MASATAKA TAKENAKA, MOTOAKI SAITO, HIROSHI TANABE, KYOSUKE YAMADA, HIROKUNI TAKANO, YASUSHI IIDA, NOZOMU YANAIHARA and AIKOU OKAMOTO

Anticancer Research January 2022, 42 (1) 115-124; DOI: https://doi.org/10.21873/anticanres.15465
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Clinical Significance of Expression of Immunoadjuvant Molecules (LAG-3, TIM-3, OX-40) in Neoadjuvant Chemotherapy for Breast Cancer
YUKA ASANO, SHINICHIRO KASHIWAGI, KOJI TAKADA, SAE ISHIHARA, WATARU GOTO, TAMAMI MORISAKI, MASATSUNE SHIBUTANI, HIROAKI TANAKA, KOSEI HIRAKAWA and MASAICHI OHIRA

Anticancer Research January 2022, 42 (1) 125-136; DOI: https://doi.org/10.21873/anticanres.15466
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Clinical Impact of CYFRA 21-1 a Marker for Treatment Failure in Patients With Oropharyngeal Cancer Treated by Radio(chemo)therapy
STEFAN A. RUDHART, PHILIPP LANGEN, KRUTHIKA THANGAVELU, FRANCESCA GEHRT, PETAR STANKOVIC, THOMAS WILHELM, BORIS A. STUCK and STEPHAN HOCH

Anticancer Research January 2022, 42 (1) 137-146; DOI: https://doi.org/10.21873/anticanres.15467
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Diagnostic and Prognostic Impact of Crypt Branching in Patients With Ulcerative Colitis: A Validation Study
CORINNA LANG-SCHWARZ, CARLOS A. RUBIO and MICHAEL VIETH

Anticancer Research January 2022, 42 (1) 147-154; DOI: https://doi.org/10.21873/anticanres.15468
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Prognostic Impact of Upfront Surgery for Locally Advanced Upper Rectal Adenocarcinoma
OLIVIER MULLER, REMY SINDAYIGAYA, SANDRA CHOMICKI, ELIAS KARAM, NICOLAS TABCHOURI, NICOLAS MICHOT, DRIFFA MOUSSATA, THIERRY LECOMTE, SOPHIE CHAPET, GILLES CALAIS, URS GIGER-PABST, EPHREM SALAME and MEHDI OUAISSI

Anticancer Research January 2022, 42 (1) 155-164; DOI: https://doi.org/10.21873/anticanres.15469
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The Role of Fast and Deep PSA Response in Castration-sensitive Prostate Cancer
ROBERTO IACOVELLI, CHIARA CICCARESE, ORAZIO CAFFO, UGO DE GIORGI, UMBERTO BASSO, MARCELLO TUCCI, CLAUDIA MOSILLO, MARCO MARUZZO, FRANCESCA MAINES, CHIARA CASADEI, MICHELE MILELLA and GIAMPAOLO TORTORA

Anticancer Research January 2022, 42 (1) 165-172; DOI: https://doi.org/10.21873/anticanres.15470
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Efficacy and Safety of Lenvatinib for Patients With Advanced Hepatocellular Carcinoma: A Retrospective, Real-world Study Conducted in Japan
NAOTAKA SHIMOZATO, TADASHI NAMISAKI, AKIHIRO OKANO, MASAYA OHANA, DAISUKE KINOSHITA, TOSHIHIKO KAWASAKI, YOSUKE AIHARA, TOSHIYA NAKATANI, HIROKI KINOSHITA, TATSUICHI ANN, KO SAITO, MOTOYUKI YOSHIDA and HITOSHI YOSHIJI

Anticancer Research January 2022, 42 (1) 173-183; DOI: https://doi.org/10.21873/anticanres.15471
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Perioperative FOLFOX in Patients With Locally Advanced Oesogastric Adenocarcinoma
STANISLAS QUESADA, EMMANUELLE SAMALIN, SIMON THEZENAS, LAKHDAR KHELLAF, ANNE MOURREGOT, FABIENNE PORTALES, THIBAULT MAZARD, MARC YCHOU and ANTOINE ADENIS

Anticancer Research January 2022, 42 (1) 185-193; DOI: https://doi.org/10.21873/anticanres.15472
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ypN0 in Patients With Definitive cN-positive Status After Preoperative Treatment Is a Prognostic Factor in Esophageal Cancer
TAKAHIRO YOSHIDA, TAKESHI NISHINO, MASAKAZU GOTO, SEIYA INOUE, SATOSHI FUJIWARA, HIROMITSU TAKIZAWA, AKIRA TANGOKU, HISANORI UEHARA and YOSHIMI BANDO

Anticancer Research January 2022, 42 (1) 195-203; DOI: https://doi.org/10.21873/anticanres.15473
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Concurrent Chemoradiotherapy With Docetaxel, Cisplatin, and 5-Fluorouracil for T3 N0 Glottic Carcinoma Without Vocal Cord Fixation
RYO TOYA, TAKAHIRO WATAKABE, DAIZO MURAKAMI, TOMOHIKO MATSUYAMA, TETSUO SAITO, YOSHIYUKI FUKUGAWA, KOHEI NISHIMOTO, YORIHISA ORITA and NATSUO OYA

Anticancer Research January 2022, 42 (1) 205-209; DOI: https://doi.org/10.21873/anticanres.15474
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The Role of Indocyanine Green in Laparoscopic Low Anterior Resections for Rectal Cancer Previously Treated With Chemo-radiotherapy: A Single-center Retrospective Analysis
ANTONIO BRESCIA, EDOARDO MARIA MUTTILLO, ILARIA ANGELICONE, ISABELLA MADAFFARI, FEDERICO MAGGI, ISABELLA SPERDUTI, MARCELLO GASPARRINI and MATTIA FALCHETTO OSTI

Anticancer Research January 2022, 42 (1) 211-216; DOI: https://doi.org/10.21873/anticanres.15475
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Pancreatectomy With Artery En-bloc Resection for Pancreatic Neck/Body Cancer: A Single-arm Pilot Study
KEN-ICHI OKADA, MANABU KAWAI, SEIKO HIRONO, SHINYA HAYAMI, MOTOKI MIYAZAWA, YUJI KITAHATA, MASAKI UENO, RYOHEI KOBAYASHI, ATSUSHI MIYAMOTO, YOSHITAKA WADA, SHINICHI ASAMURA and HIROKI YAMAUE

Anticancer Research January 2022, 42 (1) 217-227; DOI: https://doi.org/10.21873/anticanres.15476
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Impact of Tumor Growth Speed of Primary Lesions on the Clinical Outcomes of Appendicular Skeletal Metastases
YOHEI ASANO, NORIO YAMAMOTO, KATSUHIRO HAYASHI, AKIHIKO TAKEUCHI, SHINJI MIWA, KENTARO IGARASHI, HIROTAKA YONEZAWA, YOSHIHIRO ARAKI, SEI MORINAGA, SHIRO SAITO, TAKAYUKI NOJIMA and HIROYUKI TSUCHIYA

Anticancer Research January 2022, 42 (1) 229-236; DOI: https://doi.org/10.21873/anticanres.15477
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Tumor Location on the Vertical Section of the Anterior Wall Is Related to Favorable Prognosis and Low Incidence of Lymph Node Metastasis in Lower-third Gastric Cancer
YUSUKE TAKASHIMA, SHUHEI KOMATSU, MASATAKA KASUGA, TAKUMA OHASHI, HIROTAKA KONISHI, ATSUSHI SHIOZAKI, TAKESHI KUBOTA, HITOSHI FUJIWARA, KAZUMA OKAMOTO and EIGO OTSUJI

Anticancer Research January 2022, 42 (1) 237-243; DOI: https://doi.org/10.21873/anticanres.15478
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Mac-2 Binding Protein Glycosylation Isomer as a Prognostic Marker for Hepatocellular Carcinoma With Sustained Virological Response
NORIFUMI HARIMOTO, SHINJI ITOH, TAKAHIRO YAMANAKA, KEI HAGIWARA, NORIHIRO ISHII, MARIKO TSUKAGOSHI, AKIRA WATANABE, KENICHIRO ARAKI, TOMOHARU YOSHIZUMI and KEN SHIRABE

Anticancer Research January 2022, 42 (1) 245-251; DOI: https://doi.org/10.21873/anticanres.15479
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Thyroid Hormones and Morphological Features of Primary Breast Cancer
AMICHAY MEIROVITZ, BENJAMIN NISMAN, TANIR M. ALLWEIS, EINAT CARMON, LUNA KADOURI, BELLA MALY, OFRA MAIMON and TAMAR PERETZ

Anticancer Research January 2022, 42 (1) 253-261; DOI: https://doi.org/10.21873/anticanres.15480
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Prognostic Value of Squamous Differentiation in Upper Tract Urothelial Carcinoma Treated With Radical Nephroureterectomy
AKINORI MINATO, HIROTSUGU NOGUCHI, RIEKO KIMURO, HARADA MIRII, NAGATA YUJIRO, YOSHITAKA HASEGAWA, IKKO TOMISAKI, KENICHI HARADA and NAOHIRO FUJIMOTO

Anticancer Research January 2022, 42 (1) 263-269; DOI: https://doi.org/10.21873/anticanres.15481
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Chloride Intracellular Channel 1 Expression Is Associated With Poor Prognosis of Lung Adenocarcinoma
YUICHIRO YASUDA, TATSUYA NAGANO, NAOE JIMBO, TATSUNORI KIRIU, RATOE SURAYA, DAISUKE HAZAMA, MASATSUGU YAMAMOTO, YOSHIMASA MANIWA, YOSHIHIRO NISHIMURA and KAZUYUKI KOBAYASHI

Anticancer Research January 2022, 42 (1) 271-277; DOI: https://doi.org/10.21873/anticanres.15482
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Clinical Significance of Serglycin Expression in Human Breast Cancer Patients
KEIKO HOSOYA, KANAE NOSAKA, TOMOHIKO SAKABE, MAKOTO WAKAHARA, YUKI OSHIMA, YOSHIMASA SUZUKI, HIROSHIGE NAKAMURA and YOSHIHISA UMEKITA

Anticancer Research January 2022, 42 (1) 279-285; DOI: https://doi.org/10.21873/anticanres.15483
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Predictive Factors of Late Cervical Lymph Node Metastasis Using Intraoral Sonography in Patients With Tongue Cancer
MASARU KONISHI, MINORU FUJITA, KIICHI SHIMABUKURO, PONGSAPAK WONGRATWANICH and NAOYA KAKIMOTO

Anticancer Research January 2022, 42 (1) 287-292; DOI: https://doi.org/10.21873/anticanres.15484
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Reirradiation Using ¹⁹⁸Au Grain Brachytherapy for Recurrent Oral Cancer Cases Previously Treated by Definitive Radiotherapy
MASARU KONISHI, YUKI TAKEUCHI, KATSUMARO KUBO, NOBUKI IMANO, IKUNO NISHIBUCHI, YUJI MURAKAMI, KIICHI SHIMABUKURO, PONGSAPAK WONGRATWANICH, NAOYA KAKIMOTO and YASUSHI NAGATA

Anticancer Research January 2022, 42 (1) 293-300; DOI: https://doi.org/10.21873/anticanres.15485
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Preoperative Masseter Muscle Sarcopenia Predicts Mortality in Patients With Oesophageal Cancer
TEPPEI KAMADA, HIRONORI OHDAIRA, EISAKU ITO, YOSHINOBU FUSE, JUNJI TAKAHASHI, KEIGO NAKASHIMA, YUICHI NAKASEKO, MASASHI YOSHIDA, KEN ETO and YUTAKA SUZUKI

Anticancer Research January 2022, 42 (1) 301-310; DOI: https://doi.org/10.21873/anticanres.15486
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The Effect of Smoking on Progression from Ductal Carcinoma In Situ to Invasive Ductal Breast Carcinoma: A Retrospective Study
KOJI TAKADA, SHINICHIRO KASHIWAGI, YUKA ASANO, WATARU GOTO, TAMAMI MORISAKI, MASATSUNE SHIBUTANI, HIROAKI TANAKA, KOSEI HIRAKAWA and MASAICHI OHIRA

Anticancer Research January 2022, 42 (1) 311-320; DOI: https://doi.org/10.21873/anticanres.15487
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Stereotactic Ablative Radiotherapy Using CyberKnife for Stage I Non-small-cell Lung Cancer: A Retrospective Analysis
KAZUHIKO HAYASHI, OSAMU SUZUKI, HIROYA SHIOMI, MASATAKA NAKAI, KEI FUJIWARA, ERINA NAKANISHI, SHOTARO TATEKAWA, TAKERO HIRATA, KEISUKE TAMARI, HARUHIKO HIRATA, SOICHIRO FUNAKI, YUJI SEO, YOSHITO TAKEDA, FUMIAKI ISOHASHI, YASUSHI SHINTANI and KAZUHIKO OGAWA

Anticancer Research January 2022, 42 (1) 321-327; DOI: https://doi.org/10.21873/anticanres.15488
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Multiparametric MRI-guided Hypofractionated Intensity-modulated Radiation Therapy With Simultaneous Integrated Boost for Glioblastoma
YUKIHIRO HAMA and ETSUKO TATE

Anticancer Research January 2022, 42 (1) 329-334; DOI: https://doi.org/10.21873/anticanres.15489
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Association of MGMT Gene Promoter Methylation With Clinicopathological Parameters in Patients With Wild-type IDH Glioblastoma
MOONSIK KIM, JIHWAN YOO, JONG HEE CHANG and SE HOON KIM

Anticancer Research January 2022, 42 (1) 335-341; DOI: https://doi.org/10.21873/anticanres.15490
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A 5% Glucose Solution for the Liquid Formulation Gemcitabine Solvent Decreases Gemcitabine-induced Vascular Pain
KAZUKI UCHIYAMA, YOSHITAKA SAITO, TATSUHIKO SAKAMOTO, YOH TAKEKUMA, YOSHITO KOMATSU and MITSURU SUGAWARA

Anticancer Research January 2022, 42 (1) 343-348; DOI: https://doi.org/10.21873/anticanres.15491
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Correlation Between Clinical Outcomes and Serum CA-125 Levels After Standard Treatment for Epithelial Ovarian Cancer
JUHUN LEE, JONG MI KIM, YOON HEE LEE, GUN OH CHONG and DAE GY HONG

Anticancer Research January 2022, 42 (1) 349-353; DOI: https://doi.org/10.21873/anticanres.15492
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Prognostic Value of Copine 1 in Patients With Renal Cell Carcinoma
IMAN M. TALAAT, EMAN ABU-GHARBIEH, AMAL HUSSEIN, MAHMOOD HACHIM, ISRAA SOBHY, MOHAMED ELADL and WASEEM EL-HUNEIDI

Anticancer Research January 2022, 42 (1) 355-362; DOI: https://doi.org/10.21873/anticanres.15493
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The Clinical Desire for Pressurized Intraperitoneal Aerosol Chemotherapy in South Korea: An Electronic Survey-based Study
EUN JI LEE, SOO JIN PARK, JEESUN LEE, JAEHEE MUN, HAERIN PAIK, AERAN SEOL, JUNHWAN KIM, GA WON YIM, SEUNG-HYUK SHIM, HEE SEUNG KIM, SUK-JOON CHANG and on behalf of the KoRIA Trial Group

Anticancer Research January 2022, 42 (1) 363-371; DOI: https://doi.org/10.21873/anticanres.15494
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Excellent Response to MEK Inhibition in an AGK-BRAF Gene Fusion Driven Carcinoma: Case Report and Literature Review
ANDREAS DOMEN, CARL VAN PAESSCHEN, KAREN ZWAENEPOEL, SUZAN LAMBIN, PATRICK PAUWELS, MARIKA RASSCHAERT, EVA SEGELOV, MARC PEETERS and HANS PRENEN

Anticancer Research January 2022, 42 (1) 373-379; DOI: https://doi.org/10.21873/anticanres.15495
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A Case of Mesenteric Desmoid Tumor Causing Bowel Obstruction After Laparoscopic Surgery
KOTA ARIMA, YOSHIHIRO KOMOHARA, TOMOYUKI UCHIHARA, KOHEI YAMASHITA, SHINICHIRO UEMURA, NORIHISA HANADA and HIDEO BABA

Anticancer Research January 2022, 42 (1) 381-384; DOI: https://doi.org/10.21873/anticanres.15496

Experimental Studies

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A Single Nucleotide Polymorphism (SNP) in the SLC22A3 Transporter Gene Is Associated With the Severity of Oral Mucositis in Multiple Myeloma Patients Receiving Autologous Stem Cell Transplant Followed by Melphalan Therapy
JUNAN LI, AVINASH K. PERSAUD, JASMINE A. JOHNSON, DOUGKAS W. SBOROV, MITCH A. PHELPS, CRAIG C. HOFMEISTER and MING J. POI

Anticancer Research January 2022, 42 (1) 385-395; DOI: https://doi.org/10.21873/anticanres.15497
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Moderate Intensity Endurance and Resistance Exercise Attenuates Cachexia in Tumor-bearing Mice
NICOLE R. WOOD, JACOB GARRITSON, ALISSA MATHIAS, JAMES M. HAUGHIAN and REID HAYWARD

Anticancer Research January 2022, 42 (1) 397-405; DOI: https://doi.org/10.21873/anticanres.15498
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High-purity Isolation for Genotyping Rare Cancer Cells from Blood Using a Microfluidic Chip Cell Sorter
MIO IKEDA, YASUHIRO KOH, JUN OYANAGI, SHUNSUKE TERAOKA, MASAYUKI ISHIGE, YUU FUJIMURA, KAZUO TAKEDA, NAHOMI TOKUDOME, YUICHI OZAWA, HIROKI UEDA and NOBUYUKI YAMAMOTO

Anticancer Research January 2022, 42 (1) 407-417; DOI: https://doi.org/10.21873/anticanres.15499
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Development of an Automatic Measurement Method for CD8 and PD-1 Positive T Cells Using Image Analysis Software
HARUO MIYATA, YASUTO AKIYAMA, AKIRA IIZUKA, RYOTA KONDOU, CHIE MAEDA, AKARI KANEMATSU, KYOKO WATANABE, TADASHI ASHIZAWA, TAKESHI NAGASHIMA, KENICHI URAKAMI, KEIICHI OHSHIMA, TAKUYA KAWATA, KOJI MURAMATSU, AKIO SHIOMI, MASANORI TERASHIMA, TAKASHI SUGINO, AKIFUMI NOTSU, KEITA MORI and KEN YAMAGUCHI

Anticancer Research January 2022, 42 (1) 419-427; DOI: https://doi.org/10.21873/anticanres.15500
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MUC1 and CD147 Are Promising Markers for the Detection of Circulating Tumor Cells in Small Cell Lung Cancer
BETTINA SAVARESE-BRENNER, MARLENE HEUGL, BARBARA RATH, CONRADIN SCHWEIZER, EVA OBERMAYR, SANDRA STICKLER and GERHARD HAMILTON

Anticancer Research January 2022, 42 (1) 429-439; DOI: https://doi.org/10.21873/anticanres.15501
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A Rare Presentation of a Non-Asian Female With Metastatic Non-small-cell Lung Cancer Harboring EGFR L747P Mutation With Clinical Response to Multi-targeted Epigenetic and EGFR Inhibition
SAMIA S. MESSEHA, MOHAMMAD A. NEZAMI, STEVEN HAGER and KARAM F.A. SOLIMAN

Anticancer Research January 2022, 42 (1) 441-447; DOI: https://doi.org/10.21873/anticanres.15502
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Clinicopathological Analysis of Non-B Non-C Hepatocellular Carcinoma Focusing on Cellular Proliferation
SHINJI MIZUOCHI, JUN AKIBA, REIICHIRO KONDO, HIRONORI KUSANO, TARO SHIOGA, KEIICHI KONDO, KANA TSUTSUI, MASAMICHI NAKAYAMA, SACHIKO OGASAWARA, YOSHIKI NAITO, OSAMU NAKASHIMA and HIROHISA YANO

Anticancer Research January 2022, 42 (1) 449-457; DOI: https://doi.org/10.21873/anticanres.15503
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CD15⁺ Bone Marrow-derived Cells Are Regulators of Immune Response in ARG1-producing Colorectal Cancer Cells
KENTA MIYOSHI, EIICHI SATO, KENJI KATSUMATA, GENTARO FUKUSHIMA, RYUTARO UDO, EMI NISHIMURA, TOMOYA TAGO, KENTA KASAHARA, JUNICHI MAZAKI, MASANOBU ENOMOTO, TETSUO ISHIZAKI, YUICHI NAGAKAWA and AKIHIKO TSUCHIDA

Anticancer Research January 2022, 42 (1) 459-470; DOI: https://doi.org/10.21873/anticanres.15504
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Blockade of GRP78 Translocation to the Cell Surface by HDAC6 Inhibition Suppresses Proliferation of Cholangiocarcinoma Cells
CHORONG KIM, SEONMIN LEE, DANBEE KIM, DA SOL LEE, EUNJUNG LEE, CHANGHOON YOO and KYU-PYO KIM

Anticancer Research January 2022, 42 (1) 471-482; DOI: https://doi.org/10.21873/anticanres.15505
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Eupatilin Suppresses Pancreatic Cancer Cells via Glucose Uptake Inhibition, AMPK Activation, and Cell Cycle Arrest
TAE HYUN PARK and HYEON SOO KIM

Anticancer Research January 2022, 42 (1) 483-491; DOI: https://doi.org/10.21873/anticanres.15506
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Nuclear Factor IA Is Down-regulated in Muscle-invasive and High-grade Bladder Cancers
MACIEJ KACZOROWSKI, JOANNA MATYSIAK, PAWEL KIELB, BARTOSZ MALKIEWICZ and AGNIESZKA HALON

Anticancer Research January 2022, 42 (1) 493-500; DOI: https://doi.org/10.21873/anticanres.15507
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Dipeptidyl Peptidase-4 from Cancer-associated Fibroblasts Stimulates the Proliferation of Scirrhous-type Gastric Cancer Cells
SHUHEI KUSHIYAMA, MASAKAZU YASHIRO, YURIE YAMAMOTO, TOMOHIRO SERA, ATSUSHI SUGIMOTO, SADAAKI NISHIMURA, SHINGO TOGANO, KENJI KURODA, TOMOHISA OKUNO, YUICHIRO MIKI and MASAICHI OHIRA

Anticancer Research January 2022, 42 (1) 501-509; DOI: https://doi.org/10.21873/anticanres.15508
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Epstein-Barr Virus-induced Gene 3 as a Novel Biomarker in Metastatic Melanoma With Infiltrating CD8⁺ T Cells: A Study Based on The Cancer Genome Atlas (TCGA)
SATORU YONEKURA

Anticancer Research January 2022, 42 (1) 511-517; DOI: https://doi.org/10.21873/anticanres.15509
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14-3-3 Sigma Protein Contributes to Hepatocyte Growth Factor-mediated Cell Proliferation and Invasion via Matrix Metalloproteinase-1 Regulation in Human Gastric Cancer
JI YOON JUNG, SUNG AE KOH, KYUNG HEE LEE and JAE RYONG KIM

Anticancer Research January 2022, 42 (1) 519-530; DOI: https://doi.org/10.21873/anticanres.15510
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Helicobacter pylori Targets in AGS Human Gastric Adenocarcinoma: In Situ Proteomic Profiling and Systematic Analysis
JAI-SING YANG, CHIA-YU KANG, CHIU-HSIAN SU, CHAO-JUNG CHEN, YU-JEN CHIU and YUAN-MAN HSU

Anticancer Research January 2022, 42 (1) 531-546; DOI: https://doi.org/10.21873/anticanres.15511
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Effect of Alpha-tocopheryl Succinate on the Cytotoxicity of Anticancer Drugs Towards Leukemia Lymphocytes
DONIKA IVANOVA, ZHIVKO ZHELEV, GENOVEVA ZLATEVA, DESSISLAVA LAZAROVA, ZVEZDELINA YANEVA, RADMILA PANOVSKA, ICHIO AOKI and RUMIANA BAKALOVA

Anticancer Research January 2022, 42 (1) 547-554; DOI: https://doi.org/10.21873/anticanres.15512
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Olaparib-induced Apoptosis Through EBNA1-ATR-p38 MAPK Signaling Pathway in Epstein-Barr Virus-positive Gastric Cancer Cells
SUNG HO MOON, NAM-SOOK PARK, MIN HYE NOH, YEONG SEOK KIM, SOON HO CHEONG and DAE YOUNG HUR

Anticancer Research January 2022, 42 (1) 555-563; DOI: https://doi.org/10.21873/anticanres.15513
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Cholesterol Depletion Modulates Drug Resistance Pathways to Sensitize Resistant Breast Cancer Cells to Tamoxifen
GABRIELLA BIANCA HENRIQUES PALMA and MANDEEP KAUR

Anticancer Research January 2022, 42 (1) 565-579; DOI: https://doi.org/10.21873/anticanres.15514
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Nerve Growth Factor in Breast Cancer Cells Promotes Axonal Growth and Expression of Calcitonin Gene-related Peptide in a Rat Model of Spinal Metastasis
AI MAZAKI, KAZUYO YAMAUCHI, SUMIHISA ORITA, KAZUHIDE INAGE, MIYAKO SUZUKI, KAZUKI FUJIMOTO, YASUHIRO SHIGA, KOHKI ABE, MASAHIRO INOUE, MASAKI NORIMOTO, TOMOTAKA UMIMURA and SEIJI OHTORI

Anticancer Research January 2022, 42 (1) 581-587; DOI: https://doi.org/10.21873/anticanres.15515
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Suppression of DYRK1A/B Drives Endoplasmic Reticulum Stress-mediated Autophagic Cell Death Through Metabolic Reprogramming in Colorectal Cancer Cells
JIEON HWANG, AREUM PARK, CHINWOO KIM, DANBI YU, HYUNGJU BYUN, MINHEE KU, JAEMOON YANG, TAE IL KIM, KYU-SUNG JEONG, KI YOUNG KIM, HYUK LEE and SANG JOON SHIN

Anticancer Research January 2022, 42 (1) 589-598; DOI: https://doi.org/10.21873/anticanres.15516
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Establishment of Patient-derived Preclinical Models for Invasive Papillary Cholangiocarcinoma
BENJAMIN MWESIGE, MI RIM LEE, YU-SUN LEE, NA YOUNG HAN, JI EUN IM, JOON-KI KIM, SUN IL CHOI, EN KYUNG HONG, A-RA JEON, SANG-JAE PARK, SANG MYUNG WOO and YUN-HEE KIM

Anticancer Research January 2022, 42 (1) 599-608; DOI: https://doi.org/10.21873/anticanres.15517
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Development of Non-alcoholic Steatohepatitis and Nodular Regenerative Hyperplasia in C57BL/6J Mice Fed a Fructose-containing Western Diet
KEN-ICHI INOUE, HIDETSUGU YAMAGISHI, TERUO JOJIMA, TERUO INOUE and SHIGERU TOYODA

Anticancer Research January 2022, 42 (1) 609-617; DOI: https://doi.org/10.21873/anticanres.15518

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