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Research ArticleClinical Studies

Anemia in Placebo Arms of Cancer Studies

JOHANNES E. WOLFF
Anticancer Research September 2021, 41 (9) 4543-4548; DOI: https://doi.org/10.21873/anticanres.15266
JOHANNES E. WOLFF
AbbVie Inc, North Chicago, IL, U.S.A.
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  • For correspondence: johannesewolff{at}gmail.com
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    Figure 1.

    The data collection includes searches done for previous publications (2, 3). For the anemia analysis presented here, the search was updated to include the complete year 2020 and the beginning of 2021. The specific search and the final list of included publications is available upon request.

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    Figure 2.

    Frequency of anemia grade ≥1 (A) and grade ≥3 (B) reported among placebo monotherapy arms of randomized cancer trials. The differences were significant (p=0.01 for grade ≥1, p=2.5×10–8 for grade ≥3) GIST: Gastrointestinal stroma tumor; Hem: haemato-oncology including leukemia and lymphoma.

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Anticancer Research
Vol. 41, Issue 9
September 2021
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Anemia in Placebo Arms of Cancer Studies
JOHANNES E. WOLFF
Anticancer Research Sep 2021, 41 (9) 4543-4548; DOI: 10.21873/anticanres.15266

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Anemia in Placebo Arms of Cancer Studies
JOHANNES E. WOLFF
Anticancer Research Sep 2021, 41 (9) 4543-4548; DOI: 10.21873/anticanres.15266
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Keywords

  • meta-analysis
  • systematic review
  • adverse events
  • placebo
  • cancer
  • Oncology
  • randomized
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