Table of Contents

Clinical Studies

• Open Access

  Cancer Detection Rates in Targeted Transperineal MRI-TRUS Elastic Fusion-guided Prostate Biopsies Performed Under Local Anesthesia

  MACIEJ JACEWICZ, ERIK RUD, KRISTINA FLOR GALTUNG, DANIYAL NOOR and EDUARD BACO

  Anticancer Research September 2021, 41 (9) 4395-4400; DOI: https://doi.org/10.21873/anticanres.15244
• Open Access

  Crypts in Asymmetric Fission in Endoscopic Biopsies from German Patients With Inflammatory Bowel Disease

  CARLOS A. RUBIO, CORINNA LANG-SCHWARZ and MICHAEL VIETH

  Anticancer Research September 2021, 41 (9) 4401-4405; DOI: https://doi.org/10.21873/anticanres.15245
• Open Access

  Sleep Disorders Prior to Adjuvant Radiation Therapy for Gynecological Malignancies

  DIRK RADES, SVENJA KOPELKE, TAMER SOROR, STEVEN E. SCHILD, SOEREN TVILSTED, TROELS W. KJAER and TOBIAS BARTSCHT

  Anticancer Research September 2021, 41 (9) 4407-4410; DOI: https://doi.org/10.21873/anticanres.15246
• Open Access

  How to Perform Curative Laparoscopic Hepatectomy for Intraoperatively Unidentified Hepatocellular Carcinoma

  MASASHI TSUNEMATSU, SHINJI ONDA, MITSURU YANAGAKI, NORIMITSU OKUI, TADASHI UWAGAWA, JUNGO YASUDA, KENEI FURUKAWA, KOICHIRO HARUKI, TAKESHI GOCHO, YOICHI TOYAMA and TORU IKEGAMI

  Anticancer Research September 2021, 41 (9) 4411-4416; DOI: https://doi.org/10.21873/anticanres.15247
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  Ovarian Serous Carcinoma With a Novel HSP90AB1 Mutation in a Patient With Synchronous Primary Fallopian Tube Serous Carcinoma

  JINPING LAI, CAILI TONG and JEREMY R. CHIEN

  Anticancer Research September 2021, 41 (9) 4417-4422; DOI: https://doi.org/10.21873/anticanres.15248
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  T2-weighted Imaging of the Breast at 1.5T Using Simultaneous Multi-slice Acceleration

  JULIA RIFFEL, STEPHAN KANNENGIESSER, STEFAN O. SCHOENBERG, ANNA K. KAISER, DANIEL OVERHOFF, PHILIPP RIFFEL and CLEMENS G. KAISER

  Anticancer Research September 2021, 41 (9) 4423-4429; DOI: https://doi.org/10.21873/anticanres.15249
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  Radical Surgery After Neoadjuvant Chemotherapy for Locally Advanced Neuroendocrine Cancer of the Cervix

  GIUSEPPE CARUSO, INNOCENZA PALAIA, VIOLANTE DI DONATO, ANGELINA PERNAZZA, ROBERTA GALLO, GIORGIA PERNIOLA, MARTINA LEOPIZZI, CARLO DELLA ROCCA, LUDOVICO MUZII and PIERLUIGI BENEDETTI PANICI

  Anticancer Research September 2021, 41 (9) 4431-4438; DOI: https://doi.org/10.21873/anticanres.15250
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  Evaluation of Pre-radiotherapy Sleep Disorders in Patients With Rectal or Anal Cancer

  DIRK RADES, SVENJA KOPELKE, TOBIAS BARTSCHT, STEVEN E. SCHILD, SOEREN TVILSTED and TROELS W. KJAER

  Anticancer Research September 2021, 41 (9) 4439-4442; DOI: https://doi.org/10.21873/anticanres.15251
• Open Access

  Renal Function Improves After the Discontinuation of Androgen Deprivation Therapy in Japanese Patients With Prostate Cancer

  HIROSHI MASUDA, AYUMI FUJIMOTO, MANATO KANESAKA, KYOKUSIN HOU, TAKAHITO SUYAMA, KAZUHIRO ARAKI, SATOKO KOJIMA and YUKIO NAYA

  Anticancer Research September 2021, 41 (9) 4443-4446; DOI: https://doi.org/10.21873/anticanres.15252
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  The Impact of Tumor-associated Macrophages on Chemoresistance via Angiogenesis in Colorectal Cancer

  MASATSUNE SHIBUTANI, SHIGETOMI NAKAO, KIYOSHI MAEDA, HISASHI NAGAHARA, SHINICHIRO KASHIWAGI, KOSEI HIRAKAWA and MASAICHI OHIRA

  Anticancer Research September 2021, 41 (9) 4447-4453; DOI: https://doi.org/10.21873/anticanres.15253
• Open Access

  Short-term Outcomes of Robot-assisted Minimally Invasive Esophagectomy Compared With Thoracoscopic or Transthoracic Esophagectomy

  EISUKE BOOKA, HIROTOSHI KIKUCHI, RYOMA HANEDA, WATARU SONEDA, SANSHIRO KAWATA, TOMOHIRO MURAKAMI, TOMOHIRO MATSUMOTO, YOSHIHIRO HIRAMATSU and HIROYA TAKEUCHI

  Anticancer Research September 2021, 41 (9) 4455-4462; DOI: https://doi.org/10.21873/anticanres.15254
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  BAI1 as a Prognostic Marker of Clear Cell Renal Cell Carcinoma (ccRCC)

  MARTIN PESTA, IVAN TRAVNICEK, VLASTIMIL KULDA, JINDRA WINDRICHOVA, HANA REZACKOVA, KATERINA HOUFKOVA, TEREZA MACANOVA, BARBORA BENDOVA, ANDREA NESTOROVA, ONDREJ HES, MILAN HORA, ONDREJ TOPOLCAN and JIRI POLIVKA

  Anticancer Research September 2021, 41 (9) 4463-4470; DOI: https://doi.org/10.21873/anticanres.15255
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  Neutrophil-to-lymphocyte Ratio as a Prognostic Factor for Colon Cancer in Elderly Patients: A Propensity Score Analysis

  JUNICHI MAZAKI, KENJI KATSUMATA, HIROKI SUJINO, RYUTARO UDO, TOMOYA TAGO, KENTA KASAHARA, HIROSHI KUWABARA, MASANOBU ENOMOTO, TETSUO ISHIZAKI, YUICHI NAGAKAWA and AKIHIKO TSUCHIDA

  Anticancer Research September 2021, 41 (9) 4471-4478; DOI: https://doi.org/10.21873/anticanres.15256
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  The Use of CT Pattern in Differentiating Non-invasive, Minimally Invasive and Invasive Variants of Lung Adenocarcinoma

  HYNEK MIRKA, JIRI FERDA, GABRIELA KRAKOROVA, JOSEF VODICKA, PETR MUKENSNABL, ONDREJ TOPOLCAN and RADEK KUCERA

  Anticancer Research September 2021, 41 (9) 4479-4482; DOI: https://doi.org/10.21873/anticanres.15257
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  Primary Perivascular Epithelioid Cell Tumor (PEComa) of the Ovary: A Case Report and Review of the Literature

  ANGIOLO GADDUCCI, CLARA UGOLINI, STEFANIA COSIO, FABIO VISTOLI, EMANUELE FEDERICO KAUFFMANN and UGO BOGGI

  Anticancer Research September 2021, 41 (9) 4483-4488; DOI: https://doi.org/10.21873/anticanres.15258
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  Clinical Significance of Chemokine Receptor CXCR4 and CCR7 mRNA Expression in Patients With Colorectal Cancer

  SHINSUKE NAGASAWA, KAZUHITO TSUCHIDA, MANABU SHIOZAWA, YUKIHIKO HIROSHIMA, YAYOI KIMURA, ITARU HASHIMOTO, HAYATO WATANABE, KAZUKI KANO, MASAKATSU NUMATA, TORU AOYAMA, SUMITO SATO, TAKANOBU YAMADA, HIROSHI TAMAGAWA, NAOTO YAMAMOTO, TAKASHI OGATA, SOICHIRO MORINAGA, NORIO YUKAWA, YASUSHI RINO, MUNETAKA MASUDA, HIROSHI SAEKI, YOHEI MIYAGI and TAKASHI OSHIMA

  Anticancer Research September 2021, 41 (9) 4489-4495; DOI: https://doi.org/10.21873/anticanres.15259
• Open Access

  E-Cadherin and Angiopoietin-2 as Potential Biomarkers for Colorectal Cancer With Peritoneal Carcinomatosis

  HEE KYUNG KIM, YAEWON YANG, SEONGGYU BYEON, YUSOOK JEONG, JIHYUN KWON, KI HYEONG LEE, SEUNG-MYOUNG SON and HYE SOOK HAN

  Anticancer Research September 2021, 41 (9) 4497-4504; DOI: https://doi.org/10.21873/anticanres.15260
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  Tumor Vascular Microenvironment of Colorectal Hepatic Metastasis and Chemotherapy Response

  HIROTAKA OKAMOTO, SHUGO SHIBA, HIROSHI IINO, MAKOTO SUDOH and DAISUKE ICHIKAWA

  Anticancer Research September 2021, 41 (9) 4505-4513; DOI: https://doi.org/10.21873/anticanres.15261
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  Prognostic Value of CD45Ro⁺ T-Cell Expression in Patients With Oral Squamous Cell Carcinoma

  KAZUSHIGE KOIKE, KOYO NISHIYAMA, HIRONARI DEHARI, KAZUHIRO OGI, TAKANORI SASAKI, SHOTA SHIMIZU, TAKASHI SASAYA, KEI TSUCHIHASHI, TOMOKO SONODA, TADASHI HASEGAWA, HIROYOSHI HIRATSUKA and AKIHIRO MIYAZAKI

  Anticancer Research September 2021, 41 (9) 4515-4522; DOI: https://doi.org/10.21873/anticanres.15262
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  Fibrin/fibrinogen Degradation Products Are Associated With Tumor Stage and Prognosis in Patients Undergoing Resection of Esophageal Cancer

  MAKOTO SAKAI, MAKOTO SOHDA, SHINTARO UCHIDA, ARISA YAMAGUCHI, TAKAYOSHI WATANABE, HIDEYUKI SAITO, YASUNARI UBUKATA, NOBUHIRO NAKAZAWA, KENGO KURIYAMA, AKIHIKO SANO, HIROOMI OGAWA, TAKEHIKO YOKOBORI, KEN SHIRABE and HIROSHI SAEKI

  Anticancer Research September 2021, 41 (9) 4523-4527; DOI: https://doi.org/10.21873/anticanres.15263
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  The Impact of Intraoperative Blood Loss on the Survival After Laparoscopic Surgery for Colorectal Cancer

  MASATSUNE SHIBUTANI, KIYOSHI MAEDA, SHINICHIRO KASHIWAGI, KOSEI HIRAKAWA and MASAICHI OHIRA

  Anticancer Research September 2021, 41 (9) 4529-4534; DOI: https://doi.org/10.21873/anticanres.15264
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  Impact of COVID-19 Pandemic on Surgical Breast Cancer Patients Undergoing Neoadjuvant Therapy: A Multicentric Study

  GIANLUCA VANNI, MARCO PELLICCIARO, FRANCESCA COMBI, SIMONA PAPI, MARCO MATERAZZO, SILVIA SEGATTINI, STEFANO RIZZA, MARCELLO CHIOCCHI, TOMMASO PERRETTA, ROSARIA MEUCCI, ILARIA PORTARENA, CHIARA ADRIANA PISTOLESE, BENEDETTO IELPO, MICHELA CAMPANELLI, GIORGIO LISI, AGOSTINO CHIARAVALLOTI, GIOVANNI TAZZIOLI and ORESTE CLAUDIO BUONOMO

  Anticancer Research September 2021, 41 (9) 4535-4542; DOI: https://doi.org/10.21873/anticanres.15265
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  Anemia in Placebo Arms of Cancer Studies

  JOHANNES E. WOLFF

  Anticancer Research September 2021, 41 (9) 4543-4548; DOI: https://doi.org/10.21873/anticanres.15266
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  Associations Between ADC Texture Analysis and Tumor Infiltrating Lymphocytes in Brain Metastasis – A Preliminary Study

  HANS-JONAS MEYER, ANNE-KATHRIN HOHN, GORDIAN PRASSE, KARL-TITUS HOFFMANN and ALEXEY SUROV

  Anticancer Research September 2021, 41 (9) 4549-4554; DOI: https://doi.org/10.21873/anticanres.15267
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  Lenvatinib Rechallenge After Ramucirumab Treatment Failure for Hepatocellular Carcinoma

  SHOHEI KOMATSU, YOSHIHIKO YANO, MASAHIRO KIDO, KAORI KURAMITSU, HIDETOSHI GON, KENJI FUKUSHIMA, TAKESHI URADE, SHINICHI SO, HIROAKI YANAGIMOTO, HIROCHIKA TOYAMA, YUZO KODAMA and TAKUMI FUKUMOTO

  Anticancer Research September 2021, 41 (9) 4555-4562; DOI: https://doi.org/10.21873/anticanres.15268
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  Cytoplasmic-only Expression of Maspin Predicts Poor Prognosis in Patients With Oral Squamous Cell Carcinoma

  MAKOTO KAWASAKI, TOMOHIKO SAKABE, ISAMU KODANI and YOSHIHISA UMEKITA

  Anticancer Research September 2021, 41 (9) 4563-4570; DOI: https://doi.org/10.21873/anticanres.15269
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  Comparison of Dose Distribution Between VMAT-SBRT and Scanning Carbon-ion Radiotherapy for Early-stage NSCLC

  DAISAKU YOSHIDA, TERUFUMI KUSUNOKI, YOSHIKI TAKAYAMA, YOHSUKE KUSANO, SHINICHI MINOHARA, KIO KANO, WATARU ANNO, KEISUKE TSUCHIDA, YOSUKE TAKAKUSAGI, NOBUTAKA MIZOGUCHI, ITSUKO SERIZAWA, TAKESHI EBARA and HIROYUKI KATOH

  Anticancer Research September 2021, 41 (9) 4571-4575; DOI: https://doi.org/10.21873/anticanres.15270
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  PD-L1 Expression and Clinicopathological Factors in Renal Cell Carcinoma: A Comparison of Antibody Clone 73-10 With Clone 28-8

  JUNICHI IKEDA, CHISATO OHE, TAKASHI YOSHIDA, HARUYUKI OHSUGI, MOTOHIKO SUGI, KOJI TSUTA and HIDEFUMI KINOSHITA

  Anticancer Research September 2021, 41 (9) 4577-4586; DOI: https://doi.org/10.21873/anticanres.15271
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  Mesonephric-like Differentiation of Ovarian Endometrioid and High-grade Serous Carcinomas: Clinicopathological and Molecular Characteristics Distinct from Those of Mesonephric-like Adenocarcinoma

  KYUE-HEE CHOI, HYUNJIN KIM, GO EUN BAE, SANG HWA LEE, HA YOUNG WOO and HYUN-SOO KIM

  Anticancer Research September 2021, 41 (9) 4587-4601; DOI: https://doi.org/10.21873/anticanres.15272
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  Real-world Experience of Niraparib in Newly-diagnosed Epithelial Ovarian Cancer

  WONKYO SHIN, JOSEPH J. NOH, SEUNG HUN BAEK, BYOUNG-GIE KIM, MYONG CHEOL LIM and SANG-YOON PARK

  Anticancer Research September 2021, 41 (9) 4603-4607; DOI: https://doi.org/10.21873/anticanres.15273
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  External Validation of ALK and ROS1 Fusions Detected Using an Oncomine Comprehensive Assay

  SO-WOON KIM, SUNG-IM DO and KIYONG NA

  Anticancer Research September 2021, 41 (9) 4609-4617; DOI: https://doi.org/10.21873/anticanres.15274
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  The Real-world Outcomes of Patients With Advanced Invasive Lobular Carcinoma of the Breast Compared With Invasive Ductal Carcinoma: A Review at a Single Institution

  JUNICHIRO WATANABE, SHOGO NAKAMOTO and TAKASHI SUGINO

  Anticancer Research September 2021, 41 (9) 4619-4627; DOI: https://doi.org/10.21873/anticanres.15275
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  A Novel Prediction Model for Colon Cancer Recurrence Using Auto-artificial Intelligence

  JUNICHI MAZAKI, KENJI KATSUMATA, YUKI OHNO, RYUTARO UDO, TOMOYA TAGO, KENTA KASAHARA, HIROSHI KUWABARA, MASANOBU ENOMOTO, TETSUO ISHIZAKI, YUICHI NAGAKAWA and AKIHIKO TSUCHIDA

  Anticancer Research September 2021, 41 (9) 4629-4636; DOI: https://doi.org/10.21873/anticanres.15276
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  Frailty Can Predict Prognosis After Hepatectomy in Patients With Colorectal Liver Metastasis

  KAZUNORI TOKUDA, YUJI MORINE, KATSUKI MIYAZAKI, SHINICHIRO YAMADA, YU SAITO, MASAAKI NISHI, TETSUYA IKEMOTO and MITSUO SHIMADA

  Anticancer Research September 2021, 41 (9) 4637-4644; DOI: https://doi.org/10.21873/anticanres.15277
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  Jagged-1 Expression Level Is Correlated With Recurrence of Stage III Colorectal Cancer in Patients Receiving Adjuvant Chemotherapy

  HONG-BEUM KIM, SEUL-BI LEE, SEONG-JUNG KIM, HEE-JEONG LEE and SANG-GON PARK

  Anticancer Research September 2021, 41 (9) 4645-4650; DOI: https://doi.org/10.21873/anticanres.15278
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  Clinically Applicable Serum Biomarkers Among 14 Candidates Associated With Recurrence of Stage II and III Colorectal Cancer

  CHAN WOOK KIM, YE JIN HA, KA HEE TAK, SEON AE ROH, SEON-KYU KIM, SEON-YOUNG KIM, YONG SUNG KIM, DONG-HYUNG CHO and JIN CHEON KIM

  Anticancer Research September 2021, 41 (9) 4651-4658; DOI: https://doi.org/10.21873/anticanres.15279