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Research ArticleClinical Studies

Nodular Lymphocyte Predominant Hodgkin Lymphoma With Aberrant Immunophenotype or Variant Histopathology: Insights From Case Series of Three Patients

GURVIN CHANDER, HANSINI DASSANAYAKE, MARIA KAPAROU, MARIA AHMED, BHUVAN KISHORE, EMMANOUIL NIKOLOUSIS and ALEXANDROS KANELLOPOULOS
Anticancer Research August 2021, 41 (8) 4017-4020; DOI: https://doi.org/10.21873/anticanres.15200
GURVIN CHANDER
1Haematology Department, Heartlands Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, U.K.
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HANSINI DASSANAYAKE
1Haematology Department, Heartlands Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, U.K.
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MARIA KAPAROU
1Haematology Department, Heartlands Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, U.K.
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MARIA AHMED
1Haematology Department, Heartlands Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, U.K.
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BHUVAN KISHORE
1Haematology Department, Heartlands Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, U.K.
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EMMANOUIL NIKOLOUSIS
1Haematology Department, Heartlands Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, U.K.
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ALEXANDROS KANELLOPOULOS
1Haematology Department, Heartlands Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, U.K.
2Haematology Department and Bone Marrow Transplantation Unit, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, U.K.
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  • For correspondence: Alexandros.kanellopoulos{at}nhs.net
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    Figure 1.

    Immunohistochemical images illustrating characteristic ‘popcorn cells’ rosetted by small lymphocytes (left panel) and neoplastic cells strongly and uniformly positive for CD30 (right panel) in the same patient sample.

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    Figure 2.

    Positron emission tomography-computed tomography images demonstrating scattered markedly avid plaque-like soft tissue lesions. The left panel illustrates this in the left lateral chest wall, and left anterior chest wall lateral to the sternum, whereas the right panel exhibits a lesion in the lower back across the midline, posterior to the paraspinal muscles.

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Anticancer Research
Vol. 41, Issue 8
August 2021
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Nodular Lymphocyte Predominant Hodgkin Lymphoma With Aberrant Immunophenotype or Variant Histopathology: Insights From Case Series of Three Patients
GURVIN CHANDER, HANSINI DASSANAYAKE, MARIA KAPAROU, MARIA AHMED, BHUVAN KISHORE, EMMANOUIL NIKOLOUSIS, ALEXANDROS KANELLOPOULOS
Anticancer Research Aug 2021, 41 (8) 4017-4020; DOI: 10.21873/anticanres.15200

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Nodular Lymphocyte Predominant Hodgkin Lymphoma With Aberrant Immunophenotype or Variant Histopathology: Insights From Case Series of Three Patients
GURVIN CHANDER, HANSINI DASSANAYAKE, MARIA KAPAROU, MARIA AHMED, BHUVAN KISHORE, EMMANOUIL NIKOLOUSIS, ALEXANDROS KANELLOPOULOS
Anticancer Research Aug 2021, 41 (8) 4017-4020; DOI: 10.21873/anticanres.15200
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Keywords

  • Aberrant immunophenotype
  • nodular lymphocyte predominant Hodgkin lymphoma
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