Impact of Renin–angiotensin System Inhibitors on the Efficacy of Anti-PD-1/PD-L1 Antibodies in NSCLC Patients

TAKEHIRO TOZUKA; NORIKO YANAGITANI; HIROSHI YOSHIDA; RYO MANABE; SHINSUKE OGUSU; RYOSUKE TSUGITOMI; HIROAKI SAKAMOTO; YOSHIAKI AMINO; RYO ARIYASU; KEN UCHIBORI; SATORU KITAZONO; MASAHIRO SEIKE; AKIHIKO GEMMA; MAKOTO NISHIO

doi:10.21873/anticanres.14980

Research ArticleClinical Studies

Impact of Renin–angiotensin System Inhibitors on the Efficacy of Anti-PD-1/PD-L1 Antibodies in NSCLC Patients

TAKEHIRO TOZUKA, NORIKO YANAGITANI, HIROSHI YOSHIDA, RYO MANABE, SHINSUKE OGUSU, RYOSUKE TSUGITOMI, HIROAKI SAKAMOTO, YOSHIAKI AMINO, RYO ARIYASU, KEN UCHIBORI, SATORU KITAZONO, MASAHIRO SEIKE, AKIHIKO GEMMA and MAKOTO NISHIO

Anticancer Research April 2021, 41 (4) 2093-2100; DOI: https://doi.org/10.21873/anticanres.14980

TAKEHIRO TOZUKA

1Department of Thoracic Medical Oncology, The Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan;

2Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan

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NORIKO YANAGITANI

1Department of Thoracic Medical Oncology, The Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan;

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HIROSHI YOSHIDA

1Department of Thoracic Medical Oncology, The Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan;

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RYO MANABE

1Department of Thoracic Medical Oncology, The Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan;

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SHINSUKE OGUSU

1Department of Thoracic Medical Oncology, The Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan;

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RYOSUKE TSUGITOMI

1Department of Thoracic Medical Oncology, The Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan;

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HIROAKI SAKAMOTO

1Department of Thoracic Medical Oncology, The Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan;

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YOSHIAKI AMINO

1Department of Thoracic Medical Oncology, The Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan;

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RYO ARIYASU

1Department of Thoracic Medical Oncology, The Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan;

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KEN UCHIBORI

1Department of Thoracic Medical Oncology, The Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan;

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SATORU KITAZONO

1Department of Thoracic Medical Oncology, The Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan;

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MASAHIRO SEIKE

2Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan

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AKIHIKO GEMMA

2Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan

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MAKOTO NISHIO

1Department of Thoracic Medical Oncology, The Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan;

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For correspondence: mnishio@jfcr.or.jp

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Anticancer Research

Vol. 41, Issue 4

April 2021

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