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Research ArticleExperimental Studies

Peroxiredoxin V Silencing Elevates Susceptibility to Doxorubicin-induced Cell Apoptosis via ROS-dependent Mitochondrial Dysfunction in AGS Gastric Cancer Cells

YONG-ZHE JIN, YI-XI GONG, YUE LIU, DAN-PING XIE, CHEN-XI REN, SEUNG-JAE LEE, HU-NAN SUN, TAEHO KWON and DONG-YUAN XU
Anticancer Research April 2021, 41 (4) 1831-1840; DOI: https://doi.org/10.21873/anticanres.14949
YONG-ZHE JIN
1School of Nursing, Yanbian University, Yanji, P.R. China;
2College of Medicine, Yanbian University, Yanji, P.R. China;
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YI-XI GONG
3College of Life Science & Technology, Heilongjiang Bayi Agricultural University, Daqing, P.R. China;
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YUE LIU
3College of Life Science & Technology, Heilongjiang Bayi Agricultural University, Daqing, P.R. China;
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DAN-PING XIE
3College of Life Science & Technology, Heilongjiang Bayi Agricultural University, Daqing, P.R. China;
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CHEN-XI REN
3College of Life Science & Technology, Heilongjiang Bayi Agricultural University, Daqing, P.R. China;
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SEUNG-JAE LEE
4Immunoregulatory Materials Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeonbuk, Republic of Korea;
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HU-NAN SUN
3College of Life Science & Technology, Heilongjiang Bayi Agricultural University, Daqing, P.R. China;
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  • For correspondence: kwon@kribb.re.kr sunhunan76@163.com dyxu@ybu.edu.cn
TAEHO KWON
5Primate Resources Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeonbuk, Republic of Korea
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  • For correspondence: kwon@kribb.re.kr sunhunan76@163.com dyxu@ybu.edu.cn
DONG-YUAN XU
2College of Medicine, Yanbian University, Yanji, P.R. China;
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  • For correspondence: kwon@kribb.re.kr sunhunan76@163.com dyxu@ybu.edu.cn
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Article Information

vol. 41 no. 4 1831-1840
DOI 
https://doi.org/10.21873/anticanres.14949
PubMed 
33813388

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received January 14, 2021
  • Revision received February 15, 2021
  • Accepted February 16, 2021
  • Published online April 3, 2021.

Copyright & Usage 
Copyright © 2021 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Author Information

  1. YONG-ZHE JIN1,2,#,
  2. YI-XI GONG3,#,
  3. YUE LIU3,#,
  4. DAN-PING XIE3,
  5. CHEN-XI REN3,
  6. SEUNG-JAE LEE4,
  7. HU-NAN SUN3⇑,
  8. TAEHO KWON5⇑ and
  9. DONG-YUAN XU2⇑
  1. 1School of Nursing, Yanbian University, Yanji, P.R. China;
  2. 2College of Medicine, Yanbian University, Yanji, P.R. China;
  3. 3College of Life Science & Technology, Heilongjiang Bayi Agricultural University, Daqing, P.R. China;
  4. 4Immunoregulatory Materials Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeonbuk, Republic of Korea;
  5. 5Primate Resources Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeonbuk, Republic of Korea
  1. Correspondence to: Taeho Kwon, Ph.D., Primate Resources Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 351-33 Neongme-gil, Ibam-myeon, Jeongeup-si, Jeonbuk, 56216, Republic of Korea. Tel: +82 635705316, Fax: +82 635705309, e-mail: kwon{at}kribb.re.kr; Hu-Nan Sun, College of Life Science & Technology, Heilongjiang Bayi Agricultural University, Xinyanglu #2, 163319, Daqing, P.R. China. Tel: +86 4596819300, Fax: +86 4596819295, e-mail: sunhunan76{at}163.com; Dong-Yuan Xu, Ph.D., College of Medicine, Yanbian University, Gongyuan Road, #977, Yanji 133000, P.R. China. Tel: +86 13894392355, e-mail: dyxu{at}ybu.edu.cn
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Anticancer Research: 41 (4)
Anticancer Research
Vol. 41, Issue 4
April 2021
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Peroxiredoxin V Silencing Elevates Susceptibility to Doxorubicin-induced Cell Apoptosis via ROS-dependent Mitochondrial Dysfunction in AGS Gastric Cancer Cells
YONG-ZHE JIN, YI-XI GONG, YUE LIU, DAN-PING XIE, CHEN-XI REN, SEUNG-JAE LEE, HU-NAN SUN, TAEHO KWON, DONG-YUAN XU
Anticancer Research Apr 2021, 41 (4) 1831-1840; DOI: 10.21873/anticanres.14949

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Peroxiredoxin V Silencing Elevates Susceptibility to Doxorubicin-induced Cell Apoptosis via ROS-dependent Mitochondrial Dysfunction in AGS Gastric Cancer Cells
YONG-ZHE JIN, YI-XI GONG, YUE LIU, DAN-PING XIE, CHEN-XI REN, SEUNG-JAE LEE, HU-NAN SUN, TAEHO KWON, DONG-YUAN XU
Anticancer Research Apr 2021, 41 (4) 1831-1840; DOI: 10.21873/anticanres.14949
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Keywords

  • Peroxiredoxin V
  • reactive oxygen species
  • apoptosis
  • mitochondria
  • gastric cancer
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