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Research ArticleExperimental Studies

Down-regulation of Glutathione Peroxidase 4 in Oral Cancer Inhibits Tumor Growth Through SREBP1 Signaling

MASAKATSU FUKUDA, YUDAI OGASAWARA, HIROYASU HAYASHI, AYAKO OKUYAMA, JUNYA SHIONO, KATSUYUKI INOUE and HIDEAKI SAKASHITA
Anticancer Research April 2021, 41 (4) 1785-1792; DOI: https://doi.org/10.21873/anticanres.14944
MASAKATSU FUKUDA
Division of Oral and Maxillofacial Surgery, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, Saitama, Japan
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  • For correspondence: fukudam@dent.meikai.ac.jp
YUDAI OGASAWARA
Division of Oral and Maxillofacial Surgery, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, Saitama, Japan
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HIROYASU HAYASHI
Division of Oral and Maxillofacial Surgery, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, Saitama, Japan
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AYAKO OKUYAMA
Division of Oral and Maxillofacial Surgery, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, Saitama, Japan
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JUNYA SHIONO
Division of Oral and Maxillofacial Surgery, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, Saitama, Japan
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KATSUYUKI INOUE
Division of Oral and Maxillofacial Surgery, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, Saitama, Japan
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HIDEAKI SAKASHITA
Division of Oral and Maxillofacial Surgery, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, Saitama, Japan
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Article Information

vol. 41 no. 4 1785-1792
DOI 
https://doi.org/10.21873/anticanres.14944
PubMed 
33813383

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received January 13, 2021
  • Revision received February 19, 2021
  • Accepted February 22, 2021
  • Published online April 3, 2021.

Copyright & Usage 
Copyright © 2021 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Author Information

  1. MASAKATSU FUKUDA⇑,
  2. YUDAI OGASAWARA,
  3. HIROYASU HAYASHI,
  4. AYAKO OKUYAMA,
  5. JUNYA SHIONO,
  6. KATSUYUKI INOUE and
  7. HIDEAKI SAKASHITA
  1. Division of Oral and Maxillofacial Surgery, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, Saitama, Japan
  1. Correspondence to: Dr. Masakatsu Fukuda, Division of Oral and Maxillofacial Surgery, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, 1-1 Keyakidai, Sakado, Saitama 350-0283, Japan. E-mail: fukudam{at}dent.meikai.ac.jp
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Anticancer Research: 41 (4)
Anticancer Research
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April 2021
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Down-regulation of Glutathione Peroxidase 4 in Oral Cancer Inhibits Tumor Growth Through SREBP1 Signaling
MASAKATSU FUKUDA, YUDAI OGASAWARA, HIROYASU HAYASHI, AYAKO OKUYAMA, JUNYA SHIONO, KATSUYUKI INOUE, HIDEAKI SAKASHITA
Anticancer Research Apr 2021, 41 (4) 1785-1792; DOI: 10.21873/anticanres.14944

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Down-regulation of Glutathione Peroxidase 4 in Oral Cancer Inhibits Tumor Growth Through SREBP1 Signaling
MASAKATSU FUKUDA, YUDAI OGASAWARA, HIROYASU HAYASHI, AYAKO OKUYAMA, JUNYA SHIONO, KATSUYUKI INOUE, HIDEAKI SAKASHITA
Anticancer Research Apr 2021, 41 (4) 1785-1792; DOI: 10.21873/anticanres.14944
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Keywords

  • Glutathione peroxidase 4
  • ferroptosis
  • SREBP
  • p53
  • human oral squamous cell carcinoma
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