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Research ArticleClinical Studies

Staged Stereotactic Radiosurgery Decreases Symptomatic Radionecrosis in Large Brain Metastasis

NEIL CHEVLI, HUI-CHUAN WANG, PRACHI DUBEY, WAQAR HAQUE, ANDREW M. FARACH, RAMIRO PINO, ROBERT C. ROSTOMILY, E. BRIAN BUTLER and BIN S. TEH
Anticancer Research March 2021, 41 (3) 1445-1449; DOI: https://doi.org/10.21873/anticanres.14902
NEIL CHEVLI
1Department of Radiation Oncology, University of Texas Medical Branch at Galveston, Galveston, TX, U.S.A.;
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HUI-CHUAN WANG
2Department of Radiation Oncology, Houston Methodist Hospital, Houston, TX, U.S.A.;
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PRACHI DUBEY
3Department of Neuroradiology, Houston Methodist Hospital, Houston, TX, U.S.A.;
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WAQAR HAQUE
2Department of Radiation Oncology, Houston Methodist Hospital, Houston, TX, U.S.A.;
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ANDREW M. FARACH
2Department of Radiation Oncology, Houston Methodist Hospital, Houston, TX, U.S.A.;
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RAMIRO PINO
2Department of Radiation Oncology, Houston Methodist Hospital, Houston, TX, U.S.A.;
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ROBERT C. ROSTOMILY
4Department of Neurosurgery, Houston Methodist Hospital, Houston, TX, U.S.A.
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E. BRIAN BUTLER
2Department of Radiation Oncology, Houston Methodist Hospital, Houston, TX, U.S.A.;
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BIN S. TEH
2Department of Radiation Oncology, Houston Methodist Hospital, Houston, TX, U.S.A.;
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  • For correspondence: bteh@houstonmethodist.org
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    Figure 1.

    Left parietal lesion treated with two stages of 15 Gy one month apart. A: Prior to stage one. B: Prior to stage two. C: Three months after stage one. D: Four months after stage one. E: Six months after stage one. F: Eight months after stage one.

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    Figure 2.

    Posterior right frontal lesion treated with 18 Gy in one fraction. A: Prior to treatment. B: One month after treatment. C: Three months after treatment. D: Four months after treatment. E: Six months after treatment. F: Eight months after treatment and after receiving bevacizumab.

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    Figure 3.

    Anterior right frontal lesion treated with 18 Gy in one fraction. A: Prior to treatment. B: One month after treatment. C: Three months after treatment. D: Four months after treatment. E: Six months after treatment. F: Eight months after treatment and after receiving bevacizumab.

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Anticancer Research: 41 (3)
Anticancer Research
Vol. 41, Issue 3
March 2021
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Staged Stereotactic Radiosurgery Decreases Symptomatic Radionecrosis in Large Brain Metastasis
NEIL CHEVLI, HUI-CHUAN WANG, PRACHI DUBEY, WAQAR HAQUE, ANDREW M. FARACH, RAMIRO PINO, ROBERT C. ROSTOMILY, E. BRIAN BUTLER, BIN S. TEH
Anticancer Research Mar 2021, 41 (3) 1445-1449; DOI: 10.21873/anticanres.14902

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Staged Stereotactic Radiosurgery Decreases Symptomatic Radionecrosis in Large Brain Metastasis
NEIL CHEVLI, HUI-CHUAN WANG, PRACHI DUBEY, WAQAR HAQUE, ANDREW M. FARACH, RAMIRO PINO, ROBERT C. ROSTOMILY, E. BRIAN BUTLER, BIN S. TEH
Anticancer Research Mar 2021, 41 (3) 1445-1449; DOI: 10.21873/anticanres.14902
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Keywords

  • Staged stereotactic radiosurgery
  • symptomatic radionecrosis
  • radiographical radionecrosis
  • large brain metastasis
  • fractionated stereotactic radiosurgery
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