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Research ArticleClinical Studies

The Evaluation of the Malignant Characteristics of Conjunctival Lesions Based on the Dermatoscopic Algorithm

MAGDALENA DĘBICKA-KUMELA, BOZENA ROMANOWSKA-DIXON, IZABELLA KARSKA-BASTA, JOANNA KOWAL and ANNA MARKIEWICZ
Anticancer Research February 2021, 41 (2) 895-903; DOI: https://doi.org/10.21873/anticanres.14842
MAGDALENA DĘBICKA-KUMELA
1Jagiellonian University Medical College, Faculty of Medicine, Department of Ophthalmology and Ocular Oncology, Krakow, Poland;
2Department of Ophthalmology and Ocular Oncology, University Hospital, Krakow, Poland
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BOZENA ROMANOWSKA-DIXON
1Jagiellonian University Medical College, Faculty of Medicine, Department of Ophthalmology and Ocular Oncology, Krakow, Poland;
2Department of Ophthalmology and Ocular Oncology, University Hospital, Krakow, Poland
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IZABELLA KARSKA-BASTA
1Jagiellonian University Medical College, Faculty of Medicine, Department of Ophthalmology and Ocular Oncology, Krakow, Poland;
2Department of Ophthalmology and Ocular Oncology, University Hospital, Krakow, Poland
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JOANNA KOWAL
1Jagiellonian University Medical College, Faculty of Medicine, Department of Ophthalmology and Ocular Oncology, Krakow, Poland;
2Department of Ophthalmology and Ocular Oncology, University Hospital, Krakow, Poland
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ANNA MARKIEWICZ
1Jagiellonian University Medical College, Faculty of Medicine, Department of Ophthalmology and Ocular Oncology, Krakow, Poland;
2Department of Ophthalmology and Ocular Oncology, University Hospital, Krakow, Poland
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  • For correspondence: anna.markiewicz@uj.edu.pl annamarkiewicz@interia.pl
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Abstract

Background/Aim: This study analysed the prevalence of the characteristics evaluated in dermatoscopy for melanocytic infiltrations of the conjunctiva with various degrees of malignancy. Patients and Methods: A total of 160 conjunctival pigmented lesions were studied. Each lesion was scored using dermatoscopic patterns and the characteristics of malignancy described by Kittler. Also, the Authors’ own clues were added to the evaluation. Results: In melanomas, the following characteristics were identified: asymmetry of the pattern and colour, larger average number of colours, the presence of grey colour, structureless area, polymorphic vessels and feeder vessels. A pattern of black dots and a black colour was typical of malignant lesions and pre-cancerous (premalignant) lesions - primary acquired melanosis (PAM) with atypia. Cysts were observed only in the group of naevi. Conclusion: The patterns evaluated with dermatoscopy are present in pigmented lesions of the conjunctiva. There are, however, some characteristics which allow differentiation between melanoma and pigmented naevus and melanosis and also between PAM.

Key Words:
  • Conjunctiva
  • melanoma
  • naevus
  • PAM
  • dermatoscopy
  • Received December 18, 2020.
  • Revision received January 4, 2021.
  • Accepted January 5, 2021.
  • Copyright © 2021 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.
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Anticancer Research: 41 (2)
Anticancer Research
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February 2021
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The Evaluation of the Malignant Characteristics of Conjunctival Lesions Based on the Dermatoscopic Algorithm
MAGDALENA DĘBICKA-KUMELA, BOZENA ROMANOWSKA-DIXON, IZABELLA KARSKA-BASTA, JOANNA KOWAL, ANNA MARKIEWICZ
Anticancer Research Feb 2021, 41 (2) 895-903; DOI: 10.21873/anticanres.14842

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The Evaluation of the Malignant Characteristics of Conjunctival Lesions Based on the Dermatoscopic Algorithm
MAGDALENA DĘBICKA-KUMELA, BOZENA ROMANOWSKA-DIXON, IZABELLA KARSKA-BASTA, JOANNA KOWAL, ANNA MARKIEWICZ
Anticancer Research Feb 2021, 41 (2) 895-903; DOI: 10.21873/anticanres.14842
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Keywords

  • Conjunctiva
  • melanoma
  • naevus
  • PAM
  • dermatoscopy
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