Epithelial-to-mesenchymal Transition Heterogeneity of Circulating Tumor Cells and Their Correlation With MDSCs and Tregs in HER2-negative Metastatic Breast Cancer Patients

MARIA A. PAPADAKI; DESPOINA AGGOURAKI; ELENI-KYRIAKI VETSIKA; NIKOLAOS XENIDIS; GALAKTEA KALLERGI; ATHANASIOS KOTSAKIS; VASSILIS GEORGOULIAS

doi:10.21873/anticanres.14817

Research ArticleExperimental Studies

Epithelial-to-mesenchymal Transition Heterogeneity of Circulating Tumor Cells and Their Correlation With MDSCs and Tregs in HER2-negative Metastatic Breast Cancer Patients

MARIA A. PAPADAKI, DESPOINA AGGOURAKI, ELENI-KYRIAKI VETSIKA, NIKOLAOS XENIDIS, GALAKTEA KALLERGI, ATHANASIOS KOTSAKIS and VASSILIS GEORGOULIAS

Anticancer Research February 2021, 41 (2) 661-670; DOI: https://doi.org/10.21873/anticanres.14817

MARIA A. PAPADAKI

1Laboratory of Translational Oncology, School of Medicine, University of Crete, Heraklion, Greece;

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DESPOINA AGGOURAKI

1Laboratory of Translational Oncology, School of Medicine, University of Crete, Heraklion, Greece;

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ELENI-KYRIAKI VETSIKA

1Laboratory of Translational Oncology, School of Medicine, University of Crete, Heraklion, Greece;

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NIKOLAOS XENIDIS

2Department of Medical Oncology, Medical School, Democritus University of Thrace, Alexandroupolis, Greece;

3Hellenic Oncology Research Group (HORG), Athens, Greece;

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GALAKTEA KALLERGI

3Hellenic Oncology Research Group (HORG), Athens, Greece;

4Department of Biology, University of Patras, Patras, Greece;

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ATHANASIOS KOTSAKIS

3Hellenic Oncology Research Group (HORG), Athens, Greece;

5Department of Medical Oncology, University Hospital of Larissa & Laboratory of Oncology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece;

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VASSILIS GEORGOULIAS

3Hellenic Oncology Research Group (HORG), Athens, Greece;

6School of Medicine, University of Crete, Heraklion, Greece

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For correspondence: georgulv@otenet.gr

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vol. 41 no. 2 661-670

DOI

https://doi.org/10.21873/anticanres.14817

PubMed

33517270

Published By

International Institute of Anticancer Research

Print ISSN

0250-7005

Online ISSN

1791-7530

History

Received December 4, 2020
Revision received January 3, 2021
Accepted January 14, 2021
Published online January 30, 2021.

Author Information

MARIA A. PAPADAKI1,*,
DESPOINA AGGOURAKI1,*,
ELENI-KYRIAKI VETSIKA1,
NIKOLAOS XENIDIS2,3,
GALAKTEA KALLERGI3,4,
ATHANASIOS KOTSAKIS3,5 and
VASSILIS GEORGOULIAS3,6,*⇑

¹Laboratory of Translational Oncology, School of Medicine, University of Crete, Heraklion, Greece;
²Department of Medical Oncology, Medical School, Democritus University of Thrace, Alexandroupolis, Greece;
³Hellenic Oncology Research Group (HORG), Athens, Greece;
⁴Department of Biology, University of Patras, Patras, Greece;
⁵Department of Medical Oncology, University Hospital of Larissa & Laboratory of Oncology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece;
⁶School of Medicine, University of Crete, Heraklion, Greece

Correspondence to: Vassilis Georgoulias, MD, Ph.D., Hellenic Oncology Research Group (HORG), Gregoriou Theologou 5, 11471, Athens, Greece. Tel: +30 2106448450, Fax: +30 2106448450, e-mail: georgulv{at}otenet.gr

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Epithelial-to-mesenchymal Transition Heterogeneity of Circulating Tumor Cells and Their Correlation With MDSCs and Tregs in HER2-negative Metastatic Breast Cancer Patients

MARIA A. PAPADAKI, DESPOINA AGGOURAKI, ELENI-KYRIAKI VETSIKA, NIKOLAOS XENIDIS, GALAKTEA KALLERGI, ATHANASIOS KOTSAKIS, VASSILIS GEORGOULIAS

Anticancer Research Feb 2021, 41 (2) 661-670; DOI: 10.21873/anticanres.14817

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Epithelial-to-mesenchymal Transition Heterogeneity of Circulating Tumor Cells and Their Correlation With MDSCs and Tregs in HER2-negative Metastatic Breast Cancer Patients

MARIA A. PAPADAKI, DESPOINA AGGOURAKI, ELENI-KYRIAKI VETSIKA, NIKOLAOS XENIDIS, GALAKTEA KALLERGI, ATHANASIOS KOTSAKIS, VASSILIS GEORGOULIAS

Anticancer Research Feb 2021, 41 (2) 661-670; DOI: 10.21873/anticanres.14817

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Keywords

CTC
MDSCs
Tregs
immune cells
breast cancer
EMT
Cancer stem cells

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