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Research ArticleExperimental Studies

Epithelial-to-mesenchymal Transition Heterogeneity of Circulating Tumor Cells and Their Correlation With MDSCs and Tregs in HER2-negative Metastatic Breast Cancer Patients

MARIA A. PAPADAKI, DESPOINA AGGOURAKI, ELENI-KYRIAKI VETSIKA, NIKOLAOS XENIDIS, GALAKTEA KALLERGI, ATHANASIOS KOTSAKIS and VASSILIS GEORGOULIAS
Anticancer Research February 2021, 41 (2) 661-670; DOI: https://doi.org/10.21873/anticanres.14817
MARIA A. PAPADAKI
1Laboratory of Translational Oncology, School of Medicine, University of Crete, Heraklion, Greece;
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DESPOINA AGGOURAKI
1Laboratory of Translational Oncology, School of Medicine, University of Crete, Heraklion, Greece;
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ELENI-KYRIAKI VETSIKA
1Laboratory of Translational Oncology, School of Medicine, University of Crete, Heraklion, Greece;
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NIKOLAOS XENIDIS
2Department of Medical Oncology, Medical School, Democritus University of Thrace, Alexandroupolis, Greece;
3Hellenic Oncology Research Group (HORG), Athens, Greece;
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GALAKTEA KALLERGI
3Hellenic Oncology Research Group (HORG), Athens, Greece;
4Department of Biology, University of Patras, Patras, Greece;
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ATHANASIOS KOTSAKIS
3Hellenic Oncology Research Group (HORG), Athens, Greece;
5Department of Medical Oncology, University Hospital of Larissa & Laboratory of Oncology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece;
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VASSILIS GEORGOULIAS
3Hellenic Oncology Research Group (HORG), Athens, Greece;
6School of Medicine, University of Crete, Heraklion, Greece
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  • For correspondence: georgulv@otenet.gr
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Article Information

vol. 41 no. 2 661-670
DOI 
https://doi.org/10.21873/anticanres.14817
PubMed 
33517270

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received December 4, 2020
  • Revision received January 3, 2021
  • Accepted January 14, 2021
  • Published online January 30, 2021.

Copyright & Usage 
Copyright © 2021 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Author Information

  1. MARIA A. PAPADAKI1,*,
  2. DESPOINA AGGOURAKI1,*,
  3. ELENI-KYRIAKI VETSIKA1,
  4. NIKOLAOS XENIDIS2,3,
  5. GALAKTEA KALLERGI3,4,
  6. ATHANASIOS KOTSAKIS3,5 and
  7. VASSILIS GEORGOULIAS3,6,*⇑
  1. 1Laboratory of Translational Oncology, School of Medicine, University of Crete, Heraklion, Greece;
  2. 2Department of Medical Oncology, Medical School, Democritus University of Thrace, Alexandroupolis, Greece;
  3. 3Hellenic Oncology Research Group (HORG), Athens, Greece;
  4. 4Department of Biology, University of Patras, Patras, Greece;
  5. 5Department of Medical Oncology, University Hospital of Larissa & Laboratory of Oncology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece;
  6. 6School of Medicine, University of Crete, Heraklion, Greece
  1. Correspondence to: Vassilis Georgoulias, MD, Ph.D., Hellenic Oncology Research Group (HORG), Gregoriou Theologou 5, 11471, Athens, Greece. Tel: +30 2106448450, Fax: +30 2106448450, e-mail: georgulv{at}otenet.gr
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Anticancer Research: 41 (2)
Anticancer Research
Vol. 41, Issue 2
February 2021
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Epithelial-to-mesenchymal Transition Heterogeneity of Circulating Tumor Cells and Their Correlation With MDSCs and Tregs in HER2-negative Metastatic Breast Cancer Patients
MARIA A. PAPADAKI, DESPOINA AGGOURAKI, ELENI-KYRIAKI VETSIKA, NIKOLAOS XENIDIS, GALAKTEA KALLERGI, ATHANASIOS KOTSAKIS, VASSILIS GEORGOULIAS
Anticancer Research Feb 2021, 41 (2) 661-670; DOI: 10.21873/anticanres.14817

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Epithelial-to-mesenchymal Transition Heterogeneity of Circulating Tumor Cells and Their Correlation With MDSCs and Tregs in HER2-negative Metastatic Breast Cancer Patients
MARIA A. PAPADAKI, DESPOINA AGGOURAKI, ELENI-KYRIAKI VETSIKA, NIKOLAOS XENIDIS, GALAKTEA KALLERGI, ATHANASIOS KOTSAKIS, VASSILIS GEORGOULIAS
Anticancer Research Feb 2021, 41 (2) 661-670; DOI: 10.21873/anticanres.14817
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Keywords

  • CTC
  • MDSCs
  • Tregs
  • immune cells
  • breast cancer
  • EMT
  • cancer stem cells
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