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Research ArticleClinical Studies

Clinical Significance of Past History of Breast Cancer Screening for the Prognosis of Triple Negative Breast Cancer

SHINGO INOUE, HIROMICHI KAWAIDA, RYO SAITO, YUKO NAKAYAMA, MASATO OHMORI, AYAKO KIMURA, KATSUTOSHI SHODA, SHINJI FURUYA, NAOHIRO HOSOMURA, HIDENORI AKAIKE, YOSHIHIKO KAWAGUCHI, HIDETAKE AMEMIYA, MAKOTO SUDO, HIROSHI KONO and DAISUKE ICHIKAWA
Anticancer Research February 2021, 41 (2) 1077-1082; DOI: https://doi.org/10.21873/anticanres.14865
SHINGO INOUE
First Department of Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan
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  • For correspondence: shingoi@yamanashi.ac.jp
HIROMICHI KAWAIDA
First Department of Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan
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RYO SAITO
First Department of Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan
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YUKO NAKAYAMA
First Department of Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan
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MASATO OHMORI
First Department of Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan
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AYAKO KIMURA
First Department of Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan
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KATSUTOSHI SHODA
First Department of Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan
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SHINJI FURUYA
First Department of Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan
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NAOHIRO HOSOMURA
First Department of Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan
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HIDENORI AKAIKE
First Department of Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan
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YOSHIHIKO KAWAGUCHI
First Department of Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan
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HIDETAKE AMEMIYA
First Department of Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan
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MAKOTO SUDO
First Department of Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan
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HIROSHI KONO
First Department of Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan
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DAISUKE ICHIKAWA
First Department of Surgery, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan
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Abstract

Background/Aim: This study examined the prognostic impact of the past history of breast cancer screening within the last 2 years (PH-BCS), for patients with triple negative breast cancer (TNBC), a subtype that carries extremely poor prognosis. Patients and Methods: Eighty-six consecutive cases with TNBC, who underwent surgery at our faculty from 2009 to 2015, were divided into two groups according to PH-BCS. Prognostic analyses for disease-free survival and overall survival between the two groups were performed. Results: The positive PH-BCS group (n=44) had a significantly better prognoses than the negative PH-BCS group (n=42) (p<0.001). No recurrent cases were observed in the positive PH-BCS group. In the negative PH-BCS group, tumor and node status and chemotherapy were indicated as significant prognostic factors, and further step-wise multivariate analysis revealed only node status as a significant prognostic factor. Conclusion: Breast cancer screening at least every 2 years may improve the prognosis of TNBC.

Key Words:
  • Triple negative breast cancer
  • breast cancer screening
  • prognosis
  • Received December 22, 2020.
  • Revision received January 8, 2021.
  • Accepted January 11, 2021.
  • Copyright © 2021 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.
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Anticancer Research: 41 (2)
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February 2021
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Clinical Significance of Past History of Breast Cancer Screening for the Prognosis of Triple Negative Breast Cancer
SHINGO INOUE, HIROMICHI KAWAIDA, RYO SAITO, YUKO NAKAYAMA, MASATO OHMORI, AYAKO KIMURA, KATSUTOSHI SHODA, SHINJI FURUYA, NAOHIRO HOSOMURA, HIDENORI AKAIKE, YOSHIHIKO KAWAGUCHI, HIDETAKE AMEMIYA, MAKOTO SUDO, HIROSHI KONO, DAISUKE ICHIKAWA
Anticancer Research Feb 2021, 41 (2) 1077-1082; DOI: 10.21873/anticanres.14865

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Clinical Significance of Past History of Breast Cancer Screening for the Prognosis of Triple Negative Breast Cancer
SHINGO INOUE, HIROMICHI KAWAIDA, RYO SAITO, YUKO NAKAYAMA, MASATO OHMORI, AYAKO KIMURA, KATSUTOSHI SHODA, SHINJI FURUYA, NAOHIRO HOSOMURA, HIDENORI AKAIKE, YOSHIHIKO KAWAGUCHI, HIDETAKE AMEMIYA, MAKOTO SUDO, HIROSHI KONO, DAISUKE ICHIKAWA
Anticancer Research Feb 2021, 41 (2) 1077-1082; DOI: 10.21873/anticanres.14865
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Keywords

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