Abstract
Background/Aim: Emergency surgery for colorectal cancer (CRC) is a high-risk procedure with high morbidity and mortality rates, especially for older patients. The relationship between patient age status and long-term outcomes is unclear. We hypothesize that patient age might be associated with long-term outcomes in patients with CRC who undergo emergency surgery. Patients and Methods: Utilizing a database of CRC patients who received emergency surgery, we examined the prognostic association of patient age. Results: The ≥80-years group was significantly associated with American Society of Anesthesiologists (ASA) physical status, bowel obstruction, N stage, shorter operating time, and less adjuvant chemotherapy (all p<0.03); and also, with shorter recurrence-free survival [multivariable hazard ratio, 2.79; 95% confidence interval, 1.13-7.21; p=0.026]. ASA status and adjuvant chemotherapy were significantly associated with recurrence-free survival (all p<0.03). Conclusion: Advanced age is associated with shorter recurrence-free survival in CRC patients who undergo emergency surgery.
Footnotes
Authors’ Contributions
KK, KM, NM, and HB participated in study conception and design. All authors participated in data acquisition. KK, and KM performed the statistical analyses. KK, and KM analyzed the data. NM and HB supervised the work. KK, KM, NM, and HB were the major contributors to manuscript preparation. All Authors contributed to the manuscript, critically revised it, and approved the final version.
Conflicts of Interest
No conflicts of interest exist in relation to this study.
Funding
This work was supported in part by a Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science [grant number 19K16750 (to K.K.)].
- Received December 22, 2020.
- Revision received January 10, 2021.
- Accepted January 11, 2021.
- Copyright © 2021 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.
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