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Research ArticleClinical Studies

Safety and Efficacy of Glass Membrane Pumping Emulsification Device in Transarterial Chemoembolization for Hepatocellular Carcinoma: First Clinical Outcomes

NORIHIRO IMAI, SHINYA YOKOYAMA, KENTA YAMAMOTO, TAKANORI ITO, YOJI ISHIZU, TAKASHI HONDA and MASATOSHI ISHIGAMI
Anticancer Research November 2021, 41 (11) 5817-5820; DOI: https://doi.org/10.21873/anticanres.15399
NORIHIRO IMAI
Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
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  • For correspondence: norihiro.imai{at}gmail.com
SHINYA YOKOYAMA
Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
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KENTA YAMAMOTO
Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
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TAKANORI ITO
Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
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YOJI ISHIZU
Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
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TAKASHI HONDA
Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
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MASATOSHI ISHIGAMI
Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
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    Figure 1.

    Representative case of transarterial chemoembolization using a glass membrane pumping emulsification device. A 45 mm hepatocellular carcinoma was treated by transarterial chemoembolization using a glass membrane pumping emulsification device. A total of 4.5 ml of the emulsion was injected into the tumor-feeding artery, followed by embolization using 1-mm gelatin particles. A: Computed tomography (CT) during arterial portography showed contrast defect at segment 7 in the liver. B: Plain CT showed suitable deposition of ethiodized oil surrounding the tumor at the end of the treatment. C: Plain CT also showed ethiodized oil retention 1 week after the procedure. D and E: Contrast-enhanced CT showed complete response in the target nodule at 3 (D) and 10 (E) months after the treatment.

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    Figure 2.

    Local recurrence rates in target nodules after transarterial chemoembolization using a glass membrane pumping emulsification device. The graph shows the local recurrence rate calculated with the Kaplan–Meier method. The rate of local recurrence of target tumors was 5.2% at 100 days, 24.2% at 200 days, and 49.4% at 300 days.

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    Figure 3.

    Changes in liver function. The changes in markers of liver function before and 1 month after transarterial chemoembolization (TACE) using a glass membrane pumping emulsification device were assessed by paired t-tests. Changes were not significantIy different.

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Anticancer Research
Vol. 41, Issue 11
November 2021
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Safety and Efficacy of Glass Membrane Pumping Emulsification Device in Transarterial Chemoembolization for Hepatocellular Carcinoma: First Clinical Outcomes
NORIHIRO IMAI, SHINYA YOKOYAMA, KENTA YAMAMOTO, TAKANORI ITO, YOJI ISHIZU, TAKASHI HONDA, MASATOSHI ISHIGAMI
Anticancer Research Nov 2021, 41 (11) 5817-5820; DOI: 10.21873/anticanres.15399

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Safety and Efficacy of Glass Membrane Pumping Emulsification Device in Transarterial Chemoembolization for Hepatocellular Carcinoma: First Clinical Outcomes
NORIHIRO IMAI, SHINYA YOKOYAMA, KENTA YAMAMOTO, TAKANORI ITO, YOJI ISHIZU, TAKASHI HONDA, MASATOSHI ISHIGAMI
Anticancer Research Nov 2021, 41 (11) 5817-5820; DOI: 10.21873/anticanres.15399
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  • Clinical Outcomes of Use of the Porous Glass Membrane Pumping Emulsification Device During Transarterial Chemoembolization for Hepatocellular Carcinoma
  • Effectiveness of Porous Glass Membrane Pumping Emulsification Device in Transarterial Chemoembolization for Solitary Hepatocellular Carcinoma
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Keywords

  • Hepatocellular carcinoma
  • transarterial chemoembolization
  • glass membrane pumping emulsification device
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