Anticancer Research: 40 (5)

May 2020; Volume 40,Issue 5

Reviews

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Skeletal Muscle Mass Change During Chemotherapy: A Systematic Review and Meta-analysis
MIN KYEONG JANG, CHANG PARK, SUSAN HONG, HONGJIN LI, ESTHER RHEE and ARDITH Z. DOORENBOS

Anticancer Research May 2020, 40 (5) 2409-2418; DOI: https://doi.org/10.21873/anticanres.14210
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A Review of Stereotactic Body Radiation Therapy in the Management of Oligometastatic Prostate Cancer
BONAN ZHANG and MICHELLE LEECH

Anticancer Research May 2020, 40 (5) 2419-2428; DOI: https://doi.org/10.21873/anticanres.14211
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Endometriosis-associated Extraovarian Malignancies: A Challenging Question for the Clinician and the Pathologist
ANGIOLO GADDUCCI and GIAN FRANCO ZANNONI

Anticancer Research May 2020, 40 (5) 2429-2438; DOI: https://doi.org/10.21873/anticanres.14212
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Urinary Tract Large Cell Neuroendocrine Carcinoma: Diagnostic, Prognostic and Therapeutic Issues
FRANCESCA SANGUEDOLCE, BEPPE CALÒ, MARCO CHIRICO, SIMONA TORTORELLA, GIUSEPPE CARRIERI and LUIGI CORMIO

Anticancer Research May 2020, 40 (5) 2439-2447; DOI: https://doi.org/10.21873/anticanres.14213
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The Licensing Factor Cdt1 Links Cell Cycle Progression to the DNA Damage Response
ALEXANDRA KANELLOU, NICKOLAOS NIKIFOROS GIAKOUMAKIS, ANDREAS PANAGOPOULOS, SPYRIDON CHAMPERIS TSANIRAS and ZOI LYGEROU

Anticancer Research May 2020, 40 (5) 2449-2456; DOI: https://doi.org/10.21873/anticanres.14214
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ABL1-Directed Inhibitors for CML: Efficacy, Resistance and Future Perspectives
MICHELE MASSIMINO, STEFANIA STELLA, ELENA TIRRÒ, MARIA STELLA PENNISI, SILVIA RITA VITALE, ADRIANA PUMA, CHIARA ROMANO, SANDRA DI GREGORIO, CRISTINA TOMARCHIO, FRANCESCO DI RAIMONDO and LIVIA MANZELLA

Anticancer Research May 2020, 40 (5) 2457-2465; DOI: https://doi.org/10.21873/anticanres.14215

Experimental Studies

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Noncalcemic Vitamin D Hydroxyderivatives Inhibit Human Oral Squamous Cell Carcinoma and Down-regulate Hedgehog and WNT/β-Catenin Pathways
ALLEN S.W. OAK, GEORGETA BOCHEVA, TAE-KANG KIM, ANNA A. BROŻYNA, ZORICA JANJETOVIC, MOHAMMAD ATHAR, ROBERT C. TUCKEY and ANDRZEJ T. SLOMINSKI

Anticancer Research May 2020, 40 (5) 2467-2474; DOI: https://doi.org/10.21873/anticanres.14216
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Eribulin Regresses a Cisplatinum-resistant Rare-type Triple-negative Matrix-producing Breast Carcinoma Patient-derived Orthotopic Xenograft Mouse Model
JUN YAMAMOTO, TAKUYA MURATA, NORIHIKO SUGISAWA, TAKASHI HIGUCHI, YOSHIHIKO TASHIRO, HIROTO NISHINO, SACHIKO INUBUSHI, YU SUN, HYEIN LIM, KENTARO MIYAKE, KOICHIRO SHIMOYA, TSUNEHISA NOMURA, JUNICHI KUREBAYASHI, HIROKAZU TANINO, CHIHIRO HOZUMI, MICHAEL BOUVET, SHREE RAM SINGH, ITARU ENDO and ROBERT M. HOFFMAN

Anticancer Research May 2020, 40 (5) 2475-2479; DOI: https://doi.org/10.21873/anticanres.14217
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A Single Low Dose of Eribulin Regressed a Highly Aggressive Triple-negative Breast Cancer in a Patient-derived Orthotopic Xenograft Model
HYE IN LIM, JUN YAMAMOTO, SACHIKO INUBUSHI, HIROTO NISHINO, YOSHIHIKO TASHIRO, NORIHIKO SUGISAWA, QUINHONG HAN, YU SUN, HEE JUN CHOI, SEOK JIN NAM, MOON BO KIM, JI SUN LEE, CHIHIRO HOZUMI, MICHAEL BOUVET, SHREE RAM SINGH and ROBERT M. HOFFMAN

Anticancer Research May 2020, 40 (5) 2481-2485; DOI: https://doi.org/10.21873/anticanres.14218
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Gene Expression of Kallikreins in Breast Cancer Cell Lines
RAFAŁ WATROWSKI, DAN CACSIRE CASTILLO-TONG, EVA OBERMAYR and ROBERT ZEILLINGER

Anticancer Research May 2020, 40 (5) 2487-2495; DOI: https://doi.org/10.21873/anticanres.14219
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Pegylated Liposomal Doxorubicin/Oxaliplatin Chemotherapy Can Overcome Cisplatin Resistance in Spectrin αII-Overexpressing Ovarian Carcinoma
OSAMU MAEDA, HIROAKI KAJIYAMA, KIYOSUMI SHIBATA, SHIGEO NAKAMURA and FUMITAKA KIKKAWA

Anticancer Research May 2020, 40 (5) 2497-2507; DOI: https://doi.org/10.21873/anticanres.14220
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A Triple-negative Matrix-producing Breast Carcinoma Patient-derived Orthotopic Xenograft (PDOX) Mouse Model Is Sensitive to Bevacizumab and Vinorelbine, Regressed by Eribulin and Resistant to Olaparib
JUN YAMAMOTO, TAKUYA MURATA, YOSHIHIKO TASHIRO, TAKASHI HIGUCHI, NORIHIKO SUGISAWA, HIROTO NISHINO, SACHIKO INUBUSHI, YU SUN, HYEIN LIM, KENTARO MIYAKE, ATSUSHI HONGO, TSUNEHISA NOMURA, WATARU SAITOH, TAKUYA MORIYA, HIROKAZU TANINO, CHIHIRO HOZUMI, MICHAEL BOUVET, SHREE RAM SINGH, ITARU ENDO and ROBERT M. HOFFMAN

Anticancer Research May 2020, 40 (5) 2509-2514; DOI: https://doi.org/10.21873/anticanres.14221
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Recombinant Methioninase Combined With Tumor-targeting Salmonella typhimurium A1-R Induced Regression in a PDOX Mouse Model of Doxorubicin-resistant Dedifferentiated Liposarcoma
KENTARO IGARASHI, KEI KAWAGUCHI, MING ZHAO, QINGHONG HAN, YUYING TAN, TASUKU KIYUNA, KENTARO MIYAKE, TAKASHI HIGUCHI, SCOTT D. NELSON, SARAH M. DRY, YUNFENG LI, NORIO YAMAMOTO, KATSUHIRO HAYASHI, HIROAKI KIMURA, SHINJI MIWA, SHREE RAM SINGH, HIROYUKI TSUCHIYA and ROBERT M. HOFFMAN

Anticancer Research May 2020, 40 (5) 2515-2523; DOI: https://doi.org/10.21873/anticanres.14222
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Histone Methyltransferase Inhibition Has a Cytotoxic Impact on Transformed Mast Cells: Implications for Mastocytosis
SULTAN ALANAZI, FABIO RABELO MELO and GUNNAR PEJLER

Anticancer Research May 2020, 40 (5) 2525-2536; DOI: https://doi.org/10.21873/anticanres.14223
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Radiation Induces Autophagy via Histone H4 Lysine 20 Trimethylation in Non-small Cell Lung Cancer Cells
TAE-GUL LEE, SEO YUN KIM, HYE-RYOUN KIM, HYUNGGEE KIM and CHEOL HYEON KIM

Anticancer Research May 2020, 40 (5) 2537-2548; DOI: https://doi.org/10.21873/anticanres.14224
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Sonodynamically-induced Anticancer Effects of Polyethylene Glycol-Modified Carbon Nano Tubes
NAGAHIKO YUMITA, YUMIKO IWASE, SHIN-ICHIRO UMEMURA, FU-SHIH CHEN and YASUNORI MOMOSE

Anticancer Research May 2020, 40 (5) 2549-2557; DOI: https://doi.org/10.21873/anticanres.14225
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Androgen-induced Epigenetic Profiles of Polycomb and Trithorax Genes in Prostate Cancer Cells
SONGPING WANG, KRISHMA TAILOR and BERNARD KWABI-ADDO

Anticancer Research May 2020, 40 (5) 2559-2565; DOI: https://doi.org/10.21873/anticanres.14226
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High Spatial Resolution Digital Positron Emission Tomography Images With Dedicated Source-to-background Algorithm for Radiotherapy Planning
TAKAHIRO WATAKABE, RYO TOYA, TETSUO SAITO, TOMOHIKO MATSUYAMA, SHINYA SHIRAISHI, YUDAI KAI, YOSHINOBU SHIMOHIGASHI and NATSUO OYA

Anticancer Research May 2020, 40 (5) 2567-2572; DOI: https://doi.org/10.21873/anticanres.14227
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Role of Death Receptors-associated Lipid Rafts in Oxaliplatin-induced Death Mode Regulation of HepG2 Cells
SUNG-CHUL LIM, KESHAB RAJ PARAJULI and SONG IY HAN

Anticancer Research May 2020, 40 (5) 2573-2582; DOI: https://doi.org/10.21873/anticanres.14228
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Benzoxazine Dimer Analogue Targets Integrin β3 in Lung Cancer Cells and Suppresses Anoikis Resistance and Migration
NICHARAT SRIRATANASAK, NONGYAO NONPANYA, WORAWAT WATTANATHANA and PITHI CHANVORACHOTE

Anticancer Research May 2020, 40 (5) 2583-2589; DOI: https://doi.org/10.21873/anticanres.14229
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The Application of a Low-temperature Physical Plasma Device Operating Under Atmospheric Pressure Leads to the Production of Toxic NO₂
KARSTEN KLETSCHKUS, LYUBOMIR HARALAMBIEV, ANDREAS NITSCH, FELIX PFISTER, GERD KLINKMANN, AXEL KRAMER, SANDER BEKESCHUS, ALEXANDER MUSTEA and MATTHIAS B. STOPE

Anticancer Research May 2020, 40 (5) 2591-2599; DOI: https://doi.org/10.21873/anticanres.14230
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ABHD12 Knockdown Suppresses Breast Cancer Cell Proliferation, Migration and Invasion
SEMO JUN, SEOK WON KIM, JI-YEON LIM and SEON-JOO PARK

Anticancer Research May 2020, 40 (5) 2601-2611; DOI: https://doi.org/10.21873/anticanres.14231
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3PO as a Selective Inhibitor of 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 3 in A375 Human Melanoma Cells
KRZYSZTOF KOTOWSKI, STANISŁAW SUPPLITT, DANIEL WICZEW, DAWID PRZYSTUPSKI, WERONIKA BARTOSIK, JOLANTA SACZKO, JOANNA ROSSOWSKA, MAŁGORZATA DRĄG-ZALESIŃSKA, OLGA MICHEL and JULITA KULBACKA

Anticancer Research May 2020, 40 (5) 2613-2625; DOI: https://doi.org/10.21873/anticanres.14232
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Periostin Plays a Key Role in Radioresistance of Head and Neck Cancer Cells Via Epithelial-to-Mesenchymal Transition
JUNG JE PARK, YOUNG-SOOL HAH, SOMI RYU, SO YOUNG CHEON, HEE YOUNG CHO, JIN PYEONG KIM, SEONG JUN WON, JONG SIL LEE, JEONG SEOK HWA, JI HYUN SEO, HYO WON CHANG and SANG YOON KIM

Anticancer Research May 2020, 40 (5) 2627-2635; DOI: https://doi.org/10.21873/anticanres.14233
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Establishment of a Liver Transplant Patient-derived Tumor Xenograft (PDX) Model Using Cryopreserved Pancreatic Ductal Adenocarcinoma
RYOTA TANAKA, KEN KAGEYAMA, KENJIRO KIMURA, SHINPEI EGUCHI, JUN TAUCHI, HIROJI SHINKAWA, GO OHIRA, SADAAKI YAMAZOE, AKIRA YAMAMOTO, SHOGO TANAKA, RYOSUKE AMANO, HIROAKI TANAKA, MASAKAZU YASHIRO, SHOJI KUBO and MASAICHI OHIRA

Anticancer Research May 2020, 40 (5) 2637-2644; DOI: https://doi.org/10.21873/anticanres.14234
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MALAT1 Decreases the Sensitivity of Head and Neck Squamous Cell Carcinoma Cells to Radiation and Cisplatin
KITSADA KANGBOONRUANG, PATOMPON WONGTRAKOONGATE, KORNKAMON LERTSUWAN, SUPHALAK KHACHONKHAM, PIMOLPUN CHANGKAEW, PUANGPEN TANGBOONDUANGJIT, TEERADA SIRIPOON, NUTTAPONG NGAMPHAIBOON and ARTHIT CHAIROUNGDUA

Anticancer Research May 2020, 40 (5) 2645-2655; DOI: https://doi.org/10.21873/anticanres.14235
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High Nitric Oxide Adaptation in Isogenic Primary and Metastatic Head and Neck Cancer Cells
KUSUMAWADEE UTISPAN and SITTICHAI KOONTONGKAEW

Anticancer Research May 2020, 40 (5) 2657-2665; DOI: https://doi.org/10.21873/anticanres.14236
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Antitumor Effects of Pan-RAF Inhibitor LY3009120 Against Lung Cancer Cells Harboring Oncogenic BRAF Mutation
SHUNSAKU MIYAUCHI, KAZUHIKO SHIEN, TATSUAKI TAKEDA, KOTA ARAKI, KENTARO NAKATA, AKIHIRO MIURA, YUTA TAKAHASHI, EISUKE KURIHARA, YUSUKE OGOSHI, KEI NAMBA, KEN SUZAWA, HIROMASA YAMAMOTO, MIKIO OKAZAKI, JUNICHI SOH, SHUTA TOMIDA, MASAOMI YAMANE, MASAKIYO SAKAGUCHI and SHINICHI TOYOOKA

Anticancer Research May 2020, 40 (5) 2667-2673; DOI: https://doi.org/10.21873/anticanres.14237
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Inhibition of Jurkat T Cell Growth by N-farnesyl-norcantharimide Through Up-regulation of Tumor Suppressor Genes and Down-regulation of Genes for Steroid Biosynthesis, Metabolic Pathways and Fatty Acid Metabolism
JIN-YI WU, EN-TUNG TSAI, FANG-YU YANG, JUI-FENG LIN, HUI-FEN LIAO, YU-JEN CHEN and CHENG-DENG KUO

Anticancer Research May 2020, 40 (5) 2675-2685; DOI: https://doi.org/10.21873/anticanres.14238
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Urethane-induced Mammary Carcinogenesis Susceptibility in Transgenic Mice Expressing a Dominant-negative TGF-β Type II Receptor
MASA-AKI SHIBATA, EIKO SHIBATA, JUNJI MORIMOTO and YOICHI KONDO

Anticancer Research May 2020, 40 (5) 2687-2694; DOI: https://doi.org/10.21873/anticanres.14239
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Tumour Budding Is an Independent Predictive Factor of Cutaneous Squamous-cell Carcinoma Aggressiveness
GEORGIA KARAYANNOPOULOU, ELEFTHERIOS PANTERIS and JEAN KANITAKIS

Anticancer Research May 2020, 40 (5) 2695-2699; DOI: https://doi.org/10.21873/anticanres.14240
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A Rat Model of Oral Mucositis Induced by Cancer Chemotherapy for Quantitative Experiments
ISSEI TAKEUCHI, RIKO KAWAMATA and KIMIKO MAKINO

Anticancer Research May 2020, 40 (5) 2701-2706; DOI: https://doi.org/10.21873/anticanres.14241
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Adjuvant Postoperative CD40 Agonist and PD-1 Antagonist Combination Therapy in Syngeneic Tongue Cancer Mouse Model
SOON-HYUN AHN, SEULKI SONG and SORA KIM

Anticancer Research May 2020, 40 (5) 2707-2713; DOI: https://doi.org/10.21873/anticanres.14242
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Tumor-associated Macrophages Facilitate Bladder Cancer Progression by Increasing Cell Growth, Migration, Invasion and Cytokine Expression
CHI-PING HUANG, LIAN-XIU LIU and CHIH-RONG SHYR

Anticancer Research May 2020, 40 (5) 2715-2724; DOI: https://doi.org/10.21873/anticanres.14243
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Glioblastoma Factors Increase the Migration of Human Brain Endothelial Cells In Vitro by Increasing MMP-9/CXCR4 Levels
LUCIANE VIEIRA DE OLIVEIRA ROSARIO, BARBARA GOMES DA ROSA, THAYNAN LOPES GONCALVES, DIANA ISABEL LOURENCO MATIAS, CATARINA FREITAS and VALERIA PEREIRA FERRER

Anticancer Research May 2020, 40 (5) 2725-2737; DOI: https://doi.org/10.21873/anticanres.14244
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Cell Cycle Arrest and Apoptotic Effect of 7-(4-(N-substituted carbamoylmethyl) piperazin-1-yl) Ciprofloxacin-derivative on HCT 116 and A549 Cancer Cells
RANIA ALAAELDIN, MAIIADA HASSAN NAZMY, MOHAMED ABDEL-AZIZ, GAMAL EL-DIN A. ABUO-RAHMA and MOUSTAFA FATHY

Anticancer Research May 2020, 40 (5) 2739-2749; DOI: https://doi.org/10.21873/anticanres.14245

Clinical Studies

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Utility of the Free Vascularized Fibula Flap to Reconstruct Oncologic Defects in the Upper Extremity
MATTHEW R. CLAXTON, MATTHEW B. SHIRLEY, KARIM BAKRI, PETER S. ROSE, STEVEN L. MORAN and MATTHEW T. HOUDEK

Anticancer Research May 2020, 40 (5) 2751-2755; DOI: https://doi.org/10.21873/anticanres.14246
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MRI Lymph Node Evaluation for Prediction of Metastases in Rectal Cancer
KARIN ALMLÖV, MISCHA WOISETSCHLÄGER, PER LOFTÅS, OLOF HALLBÖÖK, NILS O. ELANDER and PER SANDSTRÖM

Anticancer Research May 2020, 40 (5) 2757-2763; DOI: https://doi.org/10.21873/anticanres.14247
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Neoadjuvant Chemotherapy Reduces the Treatment-free Interval After First-line Treatment in Patients With Advanced Ovarian Cancer
ANNE WENG EKMANN-GADE, CLAUS KIM HOGDALL, SVEND AAGE ENGELHOLM and CARSTEN LINDBERG FAGO-OLSEN

Anticancer Research May 2020, 40 (5) 2765-2770; DOI: https://doi.org/10.21873/anticanres.14248
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Ultrasound-guided Percutaneous Irreversible Electroporation for Treatment of Locally Recurrent Pancreatic Cancer After Surgical Resection
CHRISTOPHER MÅNSSON, ANDERS NILSSON, PETER NYGREN and BRITT-MARIE KARLSON

Anticancer Research May 2020, 40 (5) 2771-2775; DOI: https://doi.org/10.21873/anticanres.14249
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Five Genes Associated With Survival in Patients With Lower-grade Gliomas Were Identified by Information-theoretical Analysis
KEIKO SATO, KOUJI TAHATA and KAZUNORI AKIMOTO

Anticancer Research May 2020, 40 (5) 2777-2785; DOI: https://doi.org/10.21873/anticanres.14250
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Significance of Quantitative Interferon-gamma Levels in Non-small-cell Lung Cancer Patients' Response to Immune Checkpoint Inhibitors
TOMOHIRO KANAI, HIDEKAZU SUZUKI, HIROKO YOSHIDA, AKANE MATSUSHITA, HIROMI KAWASUMI, YUMIKO SAMEJIMA, YOSHIMI NODA, SHINGO NASU, AYAKO TANAKA, NAOKO MORISHITA, SHOJI HASHIMOTO, KUNIMITSU KAWAHARA, YOSHITAKA TAMURA, NORIO OKAMOTO, TOSHIO TANAKA and TOMONORI HIRASHIMA

Anticancer Research May 2020, 40 (5) 2787-2793; DOI: https://doi.org/10.21873/anticanres.14251
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Inflammatory Liver Tumor Caused by Fasciola hepatica Mimicking Intrahepatic Cholangiocarcinoma
TAKAYOSHI KAIDA, TORU BEPPU, HIROMITSU HAYASHI, KATSUNORI IMAI, KENSUKE YAMAMURA, HIROHISA OKABE, KAZUKI MATSUMURA, DAIKI YOSHII, YOSHIHIRO KOMOHARA, SHINICHI AKAHOSHI, KOICHI DOI, YO-ICHI YAMASHITA and HIDEO BABA

Anticancer Research May 2020, 40 (5) 2795-2800; DOI: https://doi.org/10.21873/anticanres.14252
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Impact of the Lysine-urethane Adhesive TissuGlu® on Postoperative Complications and Interventions After Drain-free Mastectomy
RALF OHLINGER, RICO RUTKOWSKI, THOMAS KOHLMANN, STEFAN PAEPKE, ZAHER ALWAFAI, CAROLIN FLIEGER, SYLKE MÖLLER, FRANZISKA LENZ, MAREK ZYGMUNT and JULIA UNGER

Anticancer Research May 2020, 40 (5) 2801-2812; DOI: https://doi.org/10.21873/anticanres.14253
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Oral dosing of Recombinant Methioninase Is Associated With a 70% Drop in PSA in a Patient With Bone-metastatic Prostate Cancer and 50% Reduction in Circulating Methionine in a High-stage Ovarian Cancer Patient
QINGHONG HAN, YUYING TAN and ROBERT M. HOFFMAN

Anticancer Research May 2020, 40 (5) 2813-2819; DOI: https://doi.org/10.21873/anticanres.14254
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Two Malignancies With Differential Responses to Immune Checkpoint Inhibitors: A Case Report
SE YOUNG HAN, BALKRISHNA N. JAHAGIRDAR and ARKADIUSZ Z. DUDEK

Anticancer Research May 2020, 40 (5) 2821-2826; DOI: https://doi.org/10.21873/anticanres.14255
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Phase II Study of Docetaxel, Cisplatin, and 5-Fluorouracil Chemoradiotherapy for Unresectable Esophageal Cancer
KOSUKE TAKAHASHI, YOSHIAKI OSAKA, YOSHIHIRO OTA, TAKAFUMI WATANABE, KENICHI IWASAKI, SHINGO TACHIBANA, YUICHI NAGAKAWA, KENJI KATSUMATA and AKIHIKO TSUCHIDA

Anticancer Research May 2020, 40 (5) 2827-2832; DOI: https://doi.org/10.21873/anticanres.14256
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The Prognostic Value of the Number of Harvested Negative Lymph Nodes in Patients Treated by Esophagectomy With or Without Neoadjuvant Chemoradiation
MAXIMILIAN BRUNNER, SUSANNE MERKEL, CHRISTIAN KRAUTZ, STEPHAN KERSTING, ROBERT GRÜTZMANN and GEORG F. WEBER

Anticancer Research May 2020, 40 (5) 2833-2840; DOI: https://doi.org/10.21873/anticanres.14257
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Extra-cerebral Metastasis – An Independent Predictor of Survival in Older Patients With Brain Metastases Receiving a Local Therapy Plus Whole-Brain Radiotherapy (WBRT)
DIRK RADES, TRANG NGUYEN and STEVEN E. SCHILD

Anticancer Research May 2020, 40 (5) 2841-2845; DOI: https://doi.org/10.21873/anticanres.14258
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Evaluation of Five Survival Scores in a Cohort of Elderly Patients With Cerebral Metastasis from Non-small Cell Lung Cancer
DIRK RADES, TRANG NGUYEN, MAI TRONG KHOA, STEFAN JANSSEN and STEVEN E. SCHILD

Anticancer Research May 2020, 40 (5) 2847-2851; DOI: https://doi.org/10.21873/anticanres.14259
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Outcome and Toxicity of Carbon Ion Radiotherapy for Axial Bone and Soft Tissue Sarcomas
FRANCESCO CUCCIA, MARIA ROSARIA FIORE, AMELIA BARCELLINI, ALBERTO IANNALFI, BARBARA VISCHIONI, SARA RONCHI, MARIA BONORA, GIULIA RIVA, ALESSANDRO VAI, ANGELICA FACOETTI, LORENZO PREDA, FRANCESCA VALVO and VIVIANA VITOLO

Anticancer Research May 2020, 40 (5) 2853-2859; DOI: https://doi.org/10.21873/anticanres.14260
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Incidental Testicular Pathologies in Patients With Idiopathic Hydrocele Testis: Is Preoperative Scrotal Ultrasound Justified?
MONA KAFKA, KILIAN STROHHACKER, FRIEDRICH AIGNER, FABIAN STEINKOHL, WOLFGANG HORNINGER, RENATE PICHLER and ISABEL HEIDEGGER

Anticancer Research May 2020, 40 (5) 2861-2864; DOI: https://doi.org/10.21873/anticanres.14261
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Impact of Cytoreductive Surgery and HIPEC on Intraoperative Gastrointestinal Wall Thickness and Patient Outcomes
MICHELLE ZHIYUN CHEN, DANIEL L. CHAN, MOHAMMAD S. ALSHAHRANI, KHALED ALTOUKHI, NAYEF ALZAHRANI and DAVID L. MORRIS

Anticancer Research May 2020, 40 (5) 2865-2869; DOI: https://doi.org/10.21873/anticanres.14262
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Prognostic Significance of Neutrophil-to-lymphocyte Ratio in Luminal Breast Cancers With Low Levels of Tumour-infiltrating Lymphocytes
AYAKO BUN, YUKIE FUJIMOTO, TOMOKO HIGUCHI, ATSUSHI SATA, REIKO FUKUI, HIROMI OZAWA, YOSHIMASA MIYAGAWA, MICHIKO IMAMURA, TAKAHIRO WATANABE and YASUO MIYOSHI

Anticancer Research May 2020, 40 (5) 2871-2880; DOI: https://doi.org/10.21873/anticanres.14263
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Preoperative Neutrophil-to-lymphocyte Ratio Predicts Tumor-infiltrating CD8⁺ T Cells in Biliary Tract Cancer
RYOTA TANAKA, KENJIRO KIMURA, SHINPEI EGUCHI, JUN TAUCHI, MASATUNE SHIBUTANI, HIROJI SHINKAWA, GO OHIRA, SADAAKI YAMAZOE, SHOGO TANAKA, RYOSUKE AMANO, HIROAKI TANAKA, MASAKAZU YASHIRO, SHOJI KUBO and MASAICHI OHIRA

Anticancer Research May 2020, 40 (5) 2881-2887; DOI: https://doi.org/10.21873/anticanres.14264
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Resection for Internal Jugular Vein Thrombosis and Cervical Lymph Nodes' Involvement from Gastric Cancer
GIULIO ILLUMINATI, ROCCO PASQUA, PRISCILLA NARDI, CHIARA FRATINI, ANTONIO MINNI and CARLA GIORDANO

Anticancer Research May 2020, 40 (5) 2889-2893; DOI: https://doi.org/10.21873/anticanres.14265
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Elderly Age Is Associated With More Conservative Treatment of Invasive Melanoma
SARAH B. BATENI, ALEXANDRA J. JOHNS, ALICIA A. GINGRICH, SEPIDEH GHOLAMI, RICHARD J. BOLD, ROBERT J. CANTER and AMANDA R. KIRANE

Anticancer Research May 2020, 40 (5) 2895-2903; DOI: https://doi.org/10.21873/anticanres.14266
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Whole-bladder Radiation Therapy for Lymph Node-negative Bladder Cancer With Muscle Invasion in Elderly Patients
AKIKO ADACHI, HIDEMASA KAWAMURA, DAISAKU YOSHIDA, MASAHIRO KAWAHARA, SHIGEHIRO KUDO, TAKASHI EBARA and TAKASHI NAKANO

Anticancer Research May 2020, 40 (5) 2905-2909; DOI: https://doi.org/10.21873/anticanres.14267
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Targeted Therapy Followed by Cytotoxic Chemotherapy in Preoperative Patients With Locally Advanced Lung Adenocarcinoma
MASAYA AOKI, KAZUHIRO UEDA, TADASHI UMEHARA, GO KAMIMURA, TAKUYA TOKUNAGA, AYA HARADA-TAKEDA, KOKI MAEDA, TOSHIYUKI NAGATA, NAOYA YOKOMAKURA, KOTA KARIATSUMARI, YUTO NONAKA, NOBUHIRO IMAMURA, SHOICHIRO MORIZONO and MASAMI SATO

Anticancer Research May 2020, 40 (5) 2911-2916; DOI: https://doi.org/10.21873/anticanres.14268
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Characterization and Prognosis of Secondary Acute Myeloid Leukemia in an Asian Population: AML With Antecedent Hematological Disease Confers Worst Outcomes, Irrespective of Cytogenetic Risk
SHEEHYUN KIM, SUNG-SOO YOON, JUNSHIK HONG, DONG-YEOP SHIN, YOUNGIL KOH, JA MIN BYUN and INHO KIM

Anticancer Research May 2020, 40 (5) 2917-2924; DOI: https://doi.org/10.21873/anticanres.14269
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Quantitative Assessment of Contrast Enhancement on Contrast Enhancement Spectral Mammography (CESM) and Comparison With Qualitative Assessment
WOJCIECH RUDNICKI, SYLWIA HEINZE, TADEUSZ POPIELA, ZBIGNIEW KOJS and ELZBIETA LUCZYNSKA

Anticancer Research May 2020, 40 (5) 2925-2932; DOI: https://doi.org/10.21873/anticanres.14270
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Primary Peritoneal High-grade Serous Carcinoma Misinterpreted as Metastatic Breast Carcinoma: A Rare Encounter in Peritoneal Fluid Cytology
SUJIN PARK, EUN YOON CHO, YOUNG LYUN OH, YEON HEE PARK and HYUN-SOO KIM

Anticancer Research May 2020, 40 (5) 2933-2939; DOI: https://doi.org/10.21873/anticanres.14271
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SF3B4 Plays an Oncogenic Role in Esophageal Squamous Cell Carcinoma
SHINYA KIDOGAMI, TOMOHIRO IGUCHI, KUNIAKI SATO, YUKIHIRO YOSHIKAWA, QUINGJANG HU, SHO NAMBARA, HISATERU KOMATSU, MASAMI UEDA, YOSUKE KURODA, TAKAAKI MASUDA, MASAKI MORI, YUICHIRO DOKI and KOSHI MIMORI

Anticancer Research May 2020, 40 (5) 2941-2946; DOI: https://doi.org/10.21873/anticanres.14272
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Expression of MicroRNA in Locoregional Recurrent Rectal Cancer
NIKA KOTNIK, NADER EL-SOURANI, ULRIKE RAAP, HANS-RUDOLF RAAB, MAXIMILIAN BOCKHORN, HELGE MEYER and ACHIM TROJA

Anticancer Research May 2020, 40 (5) 2947-2953; DOI: https://doi.org/10.21873/anticanres.14273
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Efficacy and Safety of Weekly Paclitaxel in Breast Cancer With Symptomatic Bone Marrow Infiltration
ANGELIQUE DA SILVA, CHRISTELLE LEVY, DJELILA ALLOUACHE, IOANA HRAB, ADELINE MOREL, AUDREY FAVEYRIAL, KATHARINA GUNZER, ALISON JOHNSON, CARINE SEGURA, IDLIR LICAJ, GANDHI DAMAJ and GEORGE EMILE

Anticancer Research May 2020, 40 (5) 2955-2960; DOI: https://doi.org/10.21873/anticanres.14274
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Clinicopathological Significance of MTUS1 Expression in Patients With Renal Cell Carcinoma
JONGMIN SIM, YOUNG CHAN WI, HA YOUNG PARK, SUNG YUL PARK, YOUNG EUN YOON, SEONGSIK BANG, YESEUL KIM, KISEOK JANG, SEONG SAM PAIK and SU-JIN SHIN

Anticancer Research May 2020, 40 (5) 2961-2967; DOI: https://doi.org/10.21873/anticanres.14275
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Defecatory Dysfunction After Colon Cancer Resection: The Role of Inferior Mesenteric Artery Tie
ENRICO FIORI, DANIELE CROCETTI, ANTONIETTA LAMAZZA, FRANCESCA DE FELICE, GIORGIA BURRELLI SCOTTI, ANTONIO V. STERPETTI, ANDREA MINGOLI, PAOLO SAPIENZA and GIORGIO DE TOMA

Anticancer Research May 2020, 40 (5) 2969-2974; DOI: https://doi.org/10.21873/anticanres.14276
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The Role of Predictive Model Based on Quantitative Basic Magnetic Resonance Imaging in Differentiating Medulloblastoma from Ependymoma
NGUYEN MINH DUC, HUYNH QUANG HUY, CHANDRAN NADARAJAN and BILGIN KESERCI

Anticancer Research May 2020, 40 (5) 2975-2980; DOI: https://doi.org/10.21873/anticanres.14277
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A Randomized Phase II Study of Maintenance Bevacizumab, Pemetrexed or Bevacizumab Plus Pemetrexed for Advanced Non-squamous Non-small Cell Lung Cancer
HIRONORI YOSHIDA, YOUNG HAK KIM, YUICHI SAKAMORI, HIROKI NAGAI, HIROAKI OZASA, TOSHIHIKO KANEDA, HIROSHIGE YOSHIOKA, HIROAKI NAKAGAWA, KEISUKE TOMII, ASUKA OKADA, KENICHI YOSHIMURA, MASATAKA HIRABAYASHI and TOYOHIRO HIRAI

Anticancer Research May 2020, 40 (5) 2981-2987; DOI: https://doi.org/10.21873/anticanres.14278
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The Role of Magnetic Resonance Imaging in the Pre-operative Evaluation of Women Diagnosed With Atypical Endometrial Hyperplasia
CHRYSOULA G. LIAKOU, MARIA-CLELIA LA RUSSA, NIKOLAOS AKRIVOS, VICTORIA AMES, SARAH SCOTT-BARRETT, TIMOTHY J. DUNCAN, JOAQUIN J. NIETO and NIKOLAOS BURBOS

Anticancer Research May 2020, 40 (5) 2989-2993; DOI: https://doi.org/10.21873/anticanres.14279
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Building a Nomogram for Prediction of Prostate Cancer in Patients With Preoperatively Suspected Prostate Cancer
YEN CHUAN OU, KUANGH-HSI CHANG, MIN-CHE TUNG, I-JU TSAI, LI-HUA HUANG, WEI-CHUN WENG, CHAO-YU HSU, YI-SHENG LIN and TANG-YI TSAO

Anticancer Research May 2020, 40 (5) 2995-3002; DOI: https://doi.org/10.21873/anticanres.14280
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Evaluation of the Irradiated Volume of the Heart and Cardiac Substructures After Left Breast Radiotherapy
ARETI GKANTAIFI, CHRISTODOULOS PAPADOPOULOS, DESPOINA SPYROPOULOU, MARIA TOUMPOURLEKA, GEORGE ILIADIS, NIKOLAOS TSOUKALAS, GEORGE KYRGIAS and MARIA TOLIA

Anticancer Research May 2020, 40 (5) 3003-3009; DOI: https://doi.org/10.21873/anticanres.14281

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