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Research ArticleClinical Studies

Dose Adjustment of Oxaliplatin Based on Renal Function in Patients With Metastatic Colorectal Cancer

DAICHI WATANABE, HIRONORI FUJII, NOBUHISA MATSUHASHI, HIROTOSHI IIHARA, YUNAMI YAMADA, TAKUMA ISHIHARA, TAKAO TAKAHASHI, KAZUHIRO YOSHIDA and AKIO SUZUKI
Anticancer Research April 2020, 40 (4) 2379-2386; DOI: https://doi.org/10.21873/anticanres.14207
DAICHI WATANABE
1Department of Pharmacy, Gifu University Hospital, Gifu, Japan
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HIRONORI FUJII
1Department of Pharmacy, Gifu University Hospital, Gifu, Japan
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  • For correspondence: h_fujii{at}gifu-u.ac.jp
NOBUHISA MATSUHASHI
2Department of Surgical Oncology, Gifu University Graduate School of Medicine, Gifu, Japan
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HIROTOSHI IIHARA
1Department of Pharmacy, Gifu University Hospital, Gifu, Japan
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YUNAMI YAMADA
1Department of Pharmacy, Gifu University Hospital, Gifu, Japan
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TAKUMA ISHIHARA
3Gifu University Hospital, Innovative and Clinical Research Promotion Center, Gifu University, Gifu, Japan
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TAKAO TAKAHASHI
2Department of Surgical Oncology, Gifu University Graduate School of Medicine, Gifu, Japan
4Department of Frontier Science for Surgical Oncology, Gifu University Graduate School of Medicine, Gifu, Japan
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KAZUHIRO YOSHIDA
2Department of Surgical Oncology, Gifu University Graduate School of Medicine, Gifu, Japan
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AKIO SUZUKI
1Department of Pharmacy, Gifu University Hospital, Gifu, Japan
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Article Information

vol. 40 no. 4 2379-2386
DOI 
https://doi.org/10.21873/anticanres.14207
PMID 
32234941

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received February 12, 2020
  • Revision received February 26, 2020
  • Accepted February 27, 2020
  • Published online March 31, 2020.

Copyright & Usage 
Copyright© 2020, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved

Author Information

  1. DAICHI WATANABE1,
  2. HIRONORI FUJII1⇑,
  3. NOBUHISA MATSUHASHI2,
  4. HIROTOSHI IIHARA1,
  5. YUNAMI YAMADA1,
  6. TAKUMA ISHIHARA3,
  7. TAKAO TAKAHASHI2,4,
  8. KAZUHIRO YOSHIDA2 and
  9. AKIO SUZUKI1
  1. 1Department of Pharmacy, Gifu University Hospital, Gifu, Japan
  2. 2Department of Surgical Oncology, Gifu University Graduate School of Medicine, Gifu, Japan
  3. 3Gifu University Hospital, Innovative and Clinical Research Promotion Center, Gifu University, Gifu, Japan
  4. 4Department of Frontier Science for Surgical Oncology, Gifu University Graduate School of Medicine, Gifu, Japan
  1. Correspondence to: Hironori Fujii, Department of Pharmacy, Gifu University Hospital, Yanagido 1-1, Gifu 501-1194, Japan. Tel: +81 582307080, Fax: +81 582307093, e-mail: h_fujii{at}gifu-u.ac.jp
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April 2020
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Dose Adjustment of Oxaliplatin Based on Renal Function in Patients With Metastatic Colorectal Cancer
DAICHI WATANABE, HIRONORI FUJII, NOBUHISA MATSUHASHI, HIROTOSHI IIHARA, YUNAMI YAMADA, TAKUMA ISHIHARA, TAKAO TAKAHASHI, KAZUHIRO YOSHIDA, AKIO SUZUKI
Anticancer Research Apr 2020, 40 (4) 2379-2386; DOI: 10.21873/anticanres.14207

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Dose Adjustment of Oxaliplatin Based on Renal Function in Patients With Metastatic Colorectal Cancer
DAICHI WATANABE, HIRONORI FUJII, NOBUHISA MATSUHASHI, HIROTOSHI IIHARA, YUNAMI YAMADA, TAKUMA ISHIHARA, TAKAO TAKAHASHI, KAZUHIRO YOSHIDA, AKIO SUZUKI
Anticancer Research Apr 2020, 40 (4) 2379-2386; DOI: 10.21873/anticanres.14207
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  • Identification Drug Targets for Oxaliplatin-Induced Cardiotoxicity without Affecting Cancer Treatment through Inter Variability Cross-Correlation Analysis (IVCCA)
  • Efficacy and Safety of Oxaliplatin-based Regimens as First-line Chemotherapy in Elderly Patients With Metastatic Colorectal Cancer
  • Oxaliplatin-induced cardiotoxicity in mice is connected to the changes in energy metabolism in the heart tissue
  • Oxaliplatin-induced cardiotoxicity in mice is connected to the changes in energy metabolism in the heart tissue
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Keywords

  • Oxaliplatin. renal function
  • colorectal neoplasms
  • peripheral neuropathy
  • survival
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