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Research ArticleClinical Studies

The Preoperative Prognostic Nutritional Index Predicts the Development of Deep Venous Thrombosis After Pancreatic Surgery

TOMOHIRO IGUCHI, KEISHI SUGIMACHI, YOHEI MANO, MIHOKO KONO, MASAKI KAGAWA, TOMONORI NAKANOKO, HIDEO UEHARA, MASAHIKO SUGIYAMA, MITSUHIKO OTA, MASAHIKO IKEBE, MASARU MORITA and YASUSHI TOH
Anticancer Research April 2020, 40 (4) 2297-2301; DOI: https://doi.org/10.21873/anticanres.14195
TOMOHIRO IGUCHI
1Department of Hepato-Biliary Pancreatic Surgery, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan
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  • For correspondence: tomo@surg2.med.kyushu-u.ac.jp
KEISHI SUGIMACHI
1Department of Hepato-Biliary Pancreatic Surgery, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan
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YOHEI MANO
1Department of Hepato-Biliary Pancreatic Surgery, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan
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MIHOKO KONO
2Department of Cardiovascular Medicine, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan
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MASAKI KAGAWA
3Department of Gastroenterological Surgery, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan
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TOMONORI NAKANOKO
3Department of Gastroenterological Surgery, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan
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HIDEO UEHARA
3Department of Gastroenterological Surgery, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan
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MASAHIKO SUGIYAMA
3Department of Gastroenterological Surgery, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan
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MITSUHIKO OTA
3Department of Gastroenterological Surgery, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan
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MASAHIKO IKEBE
3Department of Gastroenterological Surgery, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan
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MASARU MORITA
3Department of Gastroenterological Surgery, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan
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YASUSHI TOH
3Department of Gastroenterological Surgery, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan
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Abstract

Background/Aim: Pancreatic surgery is associated with a high risk of developing deep venous thrombosis (DVT) and malnutrition. We aimed to evaluate the factors predicting the development of DVT, focusing on nutrition assessment tools. Patients and Methods: One hundred patients who underwent pancreatic surgery were postoperatively examined for DVT. We assessed the risk factors for the development of DVT after surgery. Results: Postoperative DVT was detected in 11 patients (11%). Patients who developed DVT after surgery were significantly older (p=0.016) and had higher preoperative D-dimer levels (p=0.005) than those who did not. The preoperative prognostic nutritional index (PNI) was mostly associated with the development of DVT (p=0.079). Furthermore, PNI ≤44.3, BUN >20 mg/dl, D-dimer ≥1.9 μg/ml were independent predictors for the development of DVT after surgery. Conclusion: A poor nutrition status and dehydration should be preoperatively improved for patients who are identified, as having a high risk of developing DVT after pancreatic surgery.

  • Prognostic nutritional index
  • deep venous thrombosis
  • pancreatic surgery
  • Received February 5, 2020.
  • Revision received February 13, 2020.
  • Accepted February 17, 2020.
  • Copyright© 2020, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved
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The Preoperative Prognostic Nutritional Index Predicts the Development of Deep Venous Thrombosis After Pancreatic Surgery
TOMOHIRO IGUCHI, KEISHI SUGIMACHI, YOHEI MANO, MIHOKO KONO, MASAKI KAGAWA, TOMONORI NAKANOKO, HIDEO UEHARA, MASAHIKO SUGIYAMA, MITSUHIKO OTA, MASAHIKO IKEBE, MASARU MORITA, YASUSHI TOH
Anticancer Research Apr 2020, 40 (4) 2297-2301; DOI: 10.21873/anticanres.14195

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The Preoperative Prognostic Nutritional Index Predicts the Development of Deep Venous Thrombosis After Pancreatic Surgery
TOMOHIRO IGUCHI, KEISHI SUGIMACHI, YOHEI MANO, MIHOKO KONO, MASAKI KAGAWA, TOMONORI NAKANOKO, HIDEO UEHARA, MASAHIKO SUGIYAMA, MITSUHIKO OTA, MASAHIKO IKEBE, MASARU MORITA, YASUSHI TOH
Anticancer Research Apr 2020, 40 (4) 2297-2301; DOI: 10.21873/anticanres.14195
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Keywords

  • Prognostic nutritional index
  • deep venous thrombosis
  • pancreatic surgery
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