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Research ArticleClinical Studies

Clinical Impact of FOLFOXIRI Aiming for Conversion Surgery in Unresectable Multiple Colorectal Liver Metastasis

YUJI MORINE, TETSUYA IKEMOTO, SHUICHI IWAHASHI, YU SAITO, SHINICHIRO YAMADA, CHIE TAKASU, JUN HIGASHIJIMA, SATORU IMURA and MITSUO SHIMADA
Anticancer Research September 2019, 39 (9) 5089-5096; DOI: https://doi.org/10.21873/anticanres.13703
YUJI MORINE
Department of Surgery, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan
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  • For correspondence: ymorine{at}tokushima-u.ac.jp
TETSUYA IKEMOTO
Department of Surgery, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan
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SHUICHI IWAHASHI
Department of Surgery, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan
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YU SAITO
Department of Surgery, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan
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SHINICHIRO YAMADA
Department of Surgery, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan
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CHIE TAKASU
Department of Surgery, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan
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JUN HIGASHIJIMA
Department of Surgery, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan
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SATORU IMURA
Department of Surgery, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan
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MITSUO SHIMADA
Department of Surgery, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan
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    Figure 1.

    Overall survival curves of patients with unresectable multiple CRLM according to the induction of conversion surgery.

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    Figure 2.

    Overall survival curves of patients with unresectable multiple CRLM according to the induction of conversion surgery, who received FOLFOXIRI or other regimens.

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    Figure 3.

    Representative cases of sinusoidal obstructive syndrome according to molecular agent. A: Surgical specimen of non-tumour tissue after nine courses of FOLFOXIRI with an anti-EGFR agent. B: Surgical specimen of non-tumour tissue of eight courses of FOLFOXIRI with an anti-VEGF agent.

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Anticancer Research
Vol. 39, Issue 9
September 2019
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Clinical Impact of FOLFOXIRI Aiming for Conversion Surgery in Unresectable Multiple Colorectal Liver Metastasis
YUJI MORINE, TETSUYA IKEMOTO, SHUICHI IWAHASHI, YU SAITO, SHINICHIRO YAMADA, CHIE TAKASU, JUN HIGASHIJIMA, SATORU IMURA, MITSUO SHIMADA
Anticancer Research Sep 2019, 39 (9) 5089-5096; DOI: 10.21873/anticanres.13703

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Clinical Impact of FOLFOXIRI Aiming for Conversion Surgery in Unresectable Multiple Colorectal Liver Metastasis
YUJI MORINE, TETSUYA IKEMOTO, SHUICHI IWAHASHI, YU SAITO, SHINICHIRO YAMADA, CHIE TAKASU, JUN HIGASHIJIMA, SATORU IMURA, MITSUO SHIMADA
Anticancer Research Sep 2019, 39 (9) 5089-5096; DOI: 10.21873/anticanres.13703
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  • First-line FOLFOXIRI-based Chemotherapy for Unresectable Metastatic Colorectal Cancer: Real-world Outcomes, Safety, and Conversion Surgery
  • Effects of Type of Antibody to EGFR and Hypomagnesemia on Overall Survival in First-line Treatment of Patients With Unresectable Advanced/Recurrent Colorectal Cancer
  • A Disease-specific Score for Estimating Survival After Irradiation of Bone Metastases from Colorectal Cancer
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Keywords

  • colorectal cancer
  • conversion surgery
  • FOLFOXIRI
  • liver metastasis
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