Anticancer Research: 39 (9)

September 2019; Volume 39,Issue 9

Reviews

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Treatment Algorithm for Patients With Gastric Adenocarcinoma: An Austrian Consensus on Systemic Therapy
EWALD WÖLL, WOLFGANG EISTERER, ARMIN GERGER, THOMAS KÜHR, GERALD W. PRAGER, HOLGER RUMPOLD, HERBERT ULRICH-PUR, URSULA VOGL, THOMAS WINDER, LUKAS WEISS and RICHARD GREIL

Anticancer Research September 2019, 39 (9) 4589-4596; DOI: https://doi.org/10.21873/anticanres.13638
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Renin–Angiotensin Inhibition in Combating Malignancy: A Review
TALMA ROSENTHAL and IRENE GAVRAS

Anticancer Research September 2019, 39 (9) 4597-4602; DOI: https://doi.org/10.21873/anticanres.13639
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Sarcopenia as Prognostic Factor in Lung Cancer Patients: A Systematic Review and Meta-analysis
JUDITH BUENTZEL, JUDITH HEINZ, ANNALEN BLECKMANN, CHRISTOPH BAUER, CHRISTIAN RÖVER, HANIBAL BOHNENBERGER, SHEKHAR SAHA, MARC HINTERTHANER, HASSINA BARAKI, INGO KUTSCHKA and ALEXANDER EMMERT

Anticancer Research September 2019, 39 (9) 4603-4612; DOI: https://doi.org/10.21873/anticanres.13640
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The Role of Particle Therapy in the Risk of Radio-induced Second Tumors: A Review of the Literature
ANGELICA FACOETTI, AMELIA BARCELLINI, FRANCESCA VALVO and MARCO PULLIA

Anticancer Research September 2019, 39 (9) 4613-4617; DOI: https://doi.org/10.21873/anticanres.13641
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Arterial Thrombosis in Cancer: Spotlight on the Neglected Vessels
MARIA LAURA CANALE, IRMA BISCEGLIA, CHIARA LESTUZZI, IRIS PARRINI and on behalf of ANMCO Cardio-Oncology Task Force

Anticancer Research September 2019, 39 (9) 4619-4625; DOI: https://doi.org/10.21873/anticanres.13642
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Vitamin D and Cardiovascular Disease: An Update
ARMIN ZITTERMANN and STEFAN PILZ

Anticancer Research September 2019, 39 (9) 4627-4635; DOI: https://doi.org/10.21873/anticanres.13643

Experimental Studies

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AMMECR1 Inhibits Apoptosis and Promotes Cell-cycle Progression and Proliferation of the A549 Human Lung Cancer Cell Line
HAIBO GE, NINGCHANG CHENG, XIAOFENG XU, ZHIJIAN YANG, ROBERT M. HOFFMAN and JIA ZHU

Anticancer Research September 2019, 39 (9) 4637-4642; DOI: https://doi.org/10.21873/anticanres.13644
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Immune Check Point CD40–CD40L Activates Dendritic and Effector Cells Against Human Renal Carcinoma Cells
REGINA M. HILLEBRAND, ANNABELLE VOGT, CHRISTIAN P. STRASSBURG, MARIA A. GONZALEZ-CARMONA and INGO G.H. SCHMIDT-WOLF

Anticancer Research September 2019, 39 (9) 4643-4652; DOI: https://doi.org/10.21873/anticanres.13645
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Oral Recombinant Methioninase, Combined With Oral Caffeine and Injected Cisplatinum, Overcome Cisplatinum-Resistance and Regresses Patient-derived Orthotopic Xenograft Model of Osteosarcoma
TAKASHI HIGUCHI, HIROMICHI OSHIRO, KENTARO MIYAKE, NORIHIKO SUGISAWA, QINGHONG HAN, YUYING TAN, JUNHO PARK, ZHIYING ZHANG, SAHAR RAZMJOOEI, NORIO YAMAMOTO, KATSUHIRO HAYASHI, HIROAKI KIMURA, SHINJI MIWA, KENTARO IGARASHI, MICHAEL BOUVET, SANT P. CHAWLA, SHREE RAM SINGH, HIROYUKI TSUCHIYA and ROBERT M. HOFFMAN

Anticancer Research September 2019, 39 (9) 4653-4657; DOI: https://doi.org/10.21873/anticanres.13646
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Antiproliferative Effects of Short-chain Fatty Acids on Human Colorectal Cancer Cells via Gene Expression Inhibition
TADASHI OHARA and TSUTOMU MORI

Anticancer Research September 2019, 39 (9) 4659-4666; DOI: https://doi.org/10.21873/anticanres.13647
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Oral Recombinant Methioninase Overcomes Colorectal-cancer Liver Metastasis Resistance to the Combination of 5-Fluorouracil and Oxaliplatinum in a Patient-derived Orthotopic Xenograft Mouse Model
HIROMICHI OSHIRO, YASUNORI TOME, TASUKU KIYUNA, SANG NAM YOON, THINZAR M. LWIN, QINGHONG HAN, YUYING TAN, KENTARO MIYAKE, TAKASHI HIGUCHI, NORIHIKO SUGISAWA, YUKI KATSUYA, JUN HO PARK, ZHIYING ZANG, SAHAR RAZMJOOEI, MICHAEL BOUVET, BRYAN CLARY, SHREE RAM SINGH, FUMINORI KANAYA, KOTARO NISHIDA and ROBERT M. HOFFMAN

Anticancer Research September 2019, 39 (9) 4667-4671; DOI: https://doi.org/10.21873/anticanres.13648
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High Sensitivity to Cholic Acid-induced Colonic Tumorigenesis Makes Female PIRC Rats (F344/NTac-Apc^am1137) a Suitable Model for Studying CRC-promoting Agents
CRISTINA LUCERI, ANGELO PIETRO FEMIA, MARIO D'AMBROSIO and GIOVANNA CADERNI

Anticancer Research September 2019, 39 (9) 4673-4679; DOI: https://doi.org/10.21873/anticanres.13649
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S100A8 Expression May Have a Prognostic Value in CCRCC Reflecting TNM Staging and Fuhrman Nuclear Grade
HYO JUNG AN, HYUN MIN KOH and DAE HYUN SONG

Anticancer Research September 2019, 39 (9) 4681-4685; DOI: https://doi.org/10.21873/anticanres.13650
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Propagermanium Induces NK Cell Maturation and Tends to Prolong Overall Survival of Patients With Refractory Cancer
SHOJIRO KIKUCHI, KAZUMA NOGUCHI, KEIKO WAKAI, YOKO HAMAZAKI, KATSUYUKI TOZAWA, TAKAHITO JOMORI, MITSURU SASAKO and HIROTO MIWA

Anticancer Research September 2019, 39 (9) 4687-4698; DOI: https://doi.org/10.21873/anticanres.13651
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Metformin Prevents Peritoneal Dissemination via Immune-suppressive Cells in the Tumor Microenvironment
TAKANORI HIRAYAMA, YASUHIRO NAGATA, MIKAKO NISHIDA, MITSUTOSHI MATSUO, SHINICHIRO KOBAYASHI, AKIRA YONEDA, KENGO KANETAKA, HEIICHIRO UDONO and SUSUMU EGUCHI

Anticancer Research September 2019, 39 (9) 4699-4709; DOI: https://doi.org/10.21873/anticanres.13652
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Dynamics of Circulating Tumor Cells Early After Targeting Therapy to Human EGFR-mutated Lung Cancers and HER2 Gene-amplified Gastric Cancers in Mice
AKIHIRO ITO, HAYAO NAKANISHI, MAYUMI YOSHIMURA, SEIJI ITO, YUKIHIRO SAKAO, YASUHIRO KODERA, YASUSHI YATABE and NORIO KANEDA

Anticancer Research September 2019, 39 (9) 4711-4720; DOI: https://doi.org/10.21873/anticanres.13653
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The Effects of Analgesics and Local Anesthetics on Gene Transcription Mediated by NFATc2 and Sp1 in Pancreatic Carcinoma
MANUELA MALSY, BERNHARD GRAF and ANIKA BUNDSCHERER

Anticancer Research September 2019, 39 (9) 4721-4728; DOI: https://doi.org/10.21873/anticanres.13654
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Amphiregulin/epiregulin mRNA Expression and Primary Tumor Location in Colorectal Cancer
HIDEKAZU KURAMOCHI, GO NAKAJIMA, KAZUHIKO HAYASHI, TATSUO ARAIDA and MASAKAZU YAMAMOTO

Anticancer Research September 2019, 39 (9) 4729-4736; DOI: https://doi.org/10.21873/anticanres.13655
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Inhibition of Tumor Growth and Sensitization to Sunitinib by RNA Interference Targeting Programmed Death-ligand 1 in Mouse Renal Cell Carcinoma RenCa Model
TAKUTO HARA, HIDEAKI MIYAKE, NOBUYUKI HINATA and MASATO FUJISAWA

Anticancer Research September 2019, 39 (9) 4737-4742; DOI: https://doi.org/10.21873/anticanres.13656
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Characterization of Telomerase (hTERT) in Solid and Hematopoietic Cancer Cell Lines Reveals Different Expression Patterns
LUCAS SILVA DE HOLANDA, FELIPE PANTOJA MESQUITA, MANOEL ODORICO DE MORAES-FILHO, MARIA ELISABETE AMARAL DE MORAES, RAQUEL CARVALHO MONTENEGRO, ADRHYANN JULLYANNE DE SOUSA PORTILHO and CAROLINE AQUINO MOREIRA-NUNES

Anticancer Research September 2019, 39 (9) 4743-4748; DOI: https://doi.org/10.21873/anticanres.13657
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Comparison of Pregnane X Receptor Antagonists for Enhancing the Antitumor Effect of Cisplatin
MEGUMI YASUDA, SHUICHI KISHIMOTO, MANABU AMANO and SHOJI FUKUSHIMA

Anticancer Research September 2019, 39 (9) 4749-4755; DOI: https://doi.org/10.21873/anticanres.13658
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Synergistic Antioncogenic Activity of Azacitidine and Curcumin in Myeloid Leukemia Cell Lines and Patient Samples
IVÁN MARTÍN, BLANCA NAVARRO, CARLOS SOLANO, MARISA CALABUIG, JUAN CARLOS HERNÁNDEZ-BOLUDA, PAULA AMAT, MARÍA JOSÉ REMIGIA, FRANCISCA GARCÍA, EVA VILLAMÓN and MAR TORMO

Anticancer Research September 2019, 39 (9) 4757-4766; DOI: https://doi.org/10.21873/anticanres.13659
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Association of Caspase-8 Genotypes With Bladder Cancer Risk
MENG CHEN, YUEH-TING TSAI, WEN-SHIN CHANG, LIANG-CHUN SHIH, TE-CHUN SHEN, MENG-LIANG LIN, CHE-YI CHAO, YUN-CHI WANG, CHIA-WEN TSAI and DA-TIAN BAU

Anticancer Research September 2019, 39 (9) 4767-4773; DOI: https://doi.org/10.21873/anticanres.13660
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Eribulin Suppressed Cisplatinum- and Doxorubicin-resistant Recurrent Lung Metastatic Osteosarcoma in a Patient-derived Orthotopic Xenograft Mouse Model
TASUKU KIYUNA, YASUNORI TOME, KENTARO MIYAKE, TAKASHI MURAKAMI, HIROMICHI OSHIRO, KENTARO IGARASHI, KEI KAWAGUCHI, JOHN HSU, MANISH SINGH, YUNFENG LI, SCOTT NELSON, MICHAEL BOUVET, SHREE RAM SINGH, FUMINORI KANAYA and ROBERT M. HOFFMAN

Anticancer Research September 2019, 39 (9) 4775-4779; DOI: https://doi.org/10.21873/anticanres.13661
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Combination Treatment With Sorafenib and Everolimus Regresses a Doxorubicin-resistant Osteosarcoma in a PDOX Mouse Model
TAKASHI HIGUCHI, NORIHIKO SUGISAWA, KENTARO MIYAKE, HIROMICHI OSHIRO, NORIO YAMAMOTO, KATSUHIRO HAYASHI, HIROAKI KIMURA, SHINJI MIWA, KENTARO IGARASHI, ZOEY KLINE, PAIGE BELT, SANT P. CHAWLA, MICHAEL BOUVET, SHREE RAM SINGH, HIROYUKI TSUCHIYA and ROBERT M. HOFFMAN

Anticancer Research September 2019, 39 (9) 4781-4786; DOI: https://doi.org/10.21873/anticanres.13662
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M-CSF Receptor Antagonists Inhibit the Initiation and Progression of Hepatocellular Carcinoma in Mice
YOSHIHIRO AKAZAWA, HIROSHI KONO, MICHIO HARA, SHINJI FURUYA, YUUKI NAKATA, HIROYUKI WAKANA, HISATAKA FUKUSHIMA, CHAO SUN, HIDEKI FUJII and DAISUKE ICHIKAWA

Anticancer Research September 2019, 39 (9) 4787-4794; DOI: https://doi.org/10.21873/anticanres.13663
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Thioredoxin-interacting Protein (TXNIP) Mediates Thioredoxin-dependent Antioxidant Mechanism in Endometrial Cancer Cells Treated With 1α,25-dihydroxyvitamin D₃
YESOL KIM, YEON-SUK KIM, MINJEONG KIM, JUN-MO KIM, HAE-HYEOG LEE and TAE-HEE KIM

Anticancer Research September 2019, 39 (9) 4795-4803; DOI: https://doi.org/10.21873/anticanres.13664
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Ro 90-7501 Is a Novel Radiosensitizer for Cervical Cancer Cells that Inhibits ATM Phosphorylation
KEISUKE TAMARI, KEISUKE SANO, ZHIHAO LI, YUJI SEO, KEISUKE OTANI, SHOTARO TATEKAWA, MASAYASU TORATANI, YUJI TAKAOKA, YUTAKA TAKAHASHI, KAZUMASA MINAMI, FUMIAKI ISOHASHI, MASAHIKO KOIZUMI and KAZUHIKO OGAWA

Anticancer Research September 2019, 39 (9) 4805-4810; DOI: https://doi.org/10.21873/anticanres.13665
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Blockade of γ-Glutamylcyclotransferase Enhances Docetaxel Growth Inhibition of Prostate Cancer Cells
HIROKO TAKAGI, HIROMI II, SUSUMU KAGEYAMA, EIKI HANADA, KEIKO TANIGUCHI, TAKU YOSHIYA, TOKUHIRO CHANO, AKIHIRO KAWAUCHI and SUSUMU NAKATA

Anticancer Research September 2019, 39 (9) 4811-4816; DOI: https://doi.org/10.21873/anticanres.13666
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Brexpiprazole Reduces Survivin and Reverses EGFR Tyrosine Kinase Inhibitor Resistance in Lung and Pancreatic Cancer
TOMOMI SANOMACHI, SHUHEI SUZUKI, KEITA TOGASHI, SHIZUKA SEINO, TAKASHI YOSHIOKA, CHIFUMI KITANAKA, MASASHI OKADA and MASAHIRO YAMAMOTO

Anticancer Research September 2019, 39 (9) 4817-4828; DOI: https://doi.org/10.21873/anticanres.13667
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mTORC1/2 Inhibitor Served as a More Ideal Agent Against the Growth of Mouse Lymphocytic Leukemia Both In Vitro and In Vivo
HUI-FEN LIAO, YOU-ZHU LIN, CHIH-CHIA YU, TZONG-SHYUAN TAI, SHIH-KAI HUNG, CHING-CHIEH YANG and YU-CHIEH SU

Anticancer Research September 2019, 39 (9) 4829-4835; DOI: https://doi.org/10.21873/anticanres.13668
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Anti-parasitic Drug Ivermectin Exhibits Potent Anticancer Activity Against Gemcitabine-resistant Cholangiocarcinoma In Vitro
KITTI INTUYOD, CHARIYA HAHNVAJANAWONG, PORNTIP PINLAOR and SOMCHAI PINLAOR

Anticancer Research September 2019, 39 (9) 4837-4843; DOI: https://doi.org/10.21873/anticanres.13669
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Triorganotin Isothiocyanates Affect Migration and Immune Check-point Receptors in Human Triple-negative Breast Carcinoma MDA-MB-231 Cells
LUBA HUNAKOVA, EVA HORVATHOVA, PAULINA GRONESOVA, PAVEL BOBAL, JAN OTEVREL and JULIUS BRTKO

Anticancer Research September 2019, 39 (9) 4845-4851; DOI: https://doi.org/10.21873/anticanres.13670
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Biological Characteristics and Clinical Significance of ITGB1 and RHOC in Patients With Recurrent Colorectal Cancer
YE JIN HA, KA HEE TAK, SEON-KYU KIM, CHAN WOOK KIM, JONG LYUL LEE, SEON AE ROH, DONG-HYUNG CHO, SEON-YOUNG KIM, YONG SUNG KIM and JIN CHEON KIM

Anticancer Research September 2019, 39 (9) 4853-4864; DOI: https://doi.org/10.21873/anticanres.13671
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Hypoxia-induced PGC-1α Regulates Mitochondrial Function and Tumorigenesis of Colorectal Cancer Cells
CHUL WON YUN, JUN HEE LEE and SANG HUN LEE

Anticancer Research September 2019, 39 (9) 4865-4876; DOI: https://doi.org/10.21873/anticanres.13672

Clinical Studies

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Effects of Colorectal Cancer Risk Factors on the Association Between Aspirin and Colorectal Cancer
MAX E. SEATON, ULRIKE PETERS, KAREN C. JOHNSON, CHARLES KOOPERBERG, ANDREA BAFFORD and NIHA ZUBAIR

Anticancer Research September 2019, 39 (9) 4877-4884; DOI: https://doi.org/10.21873/anticanres.13673
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Clinical Outcomes of Head and Neck Cancer Patients Who Undergo Resection, But Forgo Adjuvant Therapy
GOKOULAKRICHENANE LOGANADANE, BENJAMIN H. KANN, HENRY S. PARK, SKYLER B. JOHNSON, SARAL MEHRA, BENJAMIN L. JUDSON, AARTI BHATIA, YAZID BELKACEMI, WENDELL G. YARBROUGH, BARBARA BURTNESS and ZAIN A. HUSAIN

Anticancer Research September 2019, 39 (9) 4885-4890; DOI: https://doi.org/10.21873/anticanres.13674
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The Role of Local Therapy in Multi-focal Epithelioid Haemangioendothelioma
DANIEL TONG, ANASTASIA CONSTANTINIDOU, BODIL ENGELMANN, FLORENCE CHAMBERLAIN, KHIN THWAY, CYRIL FISHER, ANDREW HAYES, NICOS FOTIADIS, CHRISTINA MESSIOU, AISHA B. MIAH, SHANE H. ZAIDI, CHARLOTTE BENSON, WINETTE VAN DER GRAAF and ROBIN L. JONES

Anticancer Research September 2019, 39 (9) 4891-4896; DOI: https://doi.org/10.21873/anticanres.13675
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Intrauterine Progestin Therapy as a New Approach to Premalignant Endometrial Polyps: A Prospective Observational Study
ELISE THORESEN SLETTEN, MARIT ARNES, ANNE BEATE VEREIDE and ANNE ØRBO

Anticancer Research September 2019, 39 (9) 4897-4903; DOI: https://doi.org/10.21873/anticanres.13676
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Solitary Cerebral Metastases vs. High-grade Gliomas: Usefulness of Two MRI Signs in the Differential Diagnosis
CARMINE FRANCO MUCCIO, ENRICO TEDESCHI, LORENZO UGGA, RENATO CUOCOLO, GENNARO ESPOSITO and FERDINANDO CARANCI

Anticancer Research September 2019, 39 (9) 4905-4909; DOI: https://doi.org/10.21873/anticanres.13677
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Somatic Transformation in Metastatic Testicular Germ Cell Tumours – A Different Disease Entity
ANAND SHARMA, CONSTANTINE ALIFRANGIS, MARINA MILIC, MARCIA HALL, NIKHIL VASDEV, PETER WILSON, ANDREW GOGBASHIAN, DAVID HROUDA, DANIEL BERNEY and JONATHAN SHAMASH

Anticancer Research September 2019, 39 (9) 4911-4916; DOI: https://doi.org/10.21873/anticanres.13678
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Correlation of Tumor Location to Clinical Outcomes in Colorectal Cancer: A Single-institution Retrospective Analysis
CARLO SIGNORELLI, MARIO GIOVANNI CHILELLI, ISABELLA SPERDUTI, SILVANA GIACINTI, PIETRO MARIA AMODIO, RAFFAELE MACARONE PALMIERI, TERESA VALENTINA RANALLI, VITO VINCENZO GOMES, MARIA ELENA ROSETTO, FABRIZIO NELLI and ENZO MARIA RUGGERI

Anticancer Research September 2019, 39 (9) 4917-4924; DOI: https://doi.org/10.21873/anticanres.13679
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Peroxiredoxin 6 Serum Levels and Risk of Neutropenic Infections in Diffuse Large B-cell Lymphoma
ESA JARKKO MIKAEL KARI, MILLA ELVI LINNEA KUUSISTO, JAN BÖHM, KIRSI-MARIA HAAPASAARI, HANNA-RIIKKA TEPPO, PEETER KARIHTALA, ANNA HAKALAHTI, TAINA TURPEENNIEMI-HUJANEN and OUTI KUITTINEN

Anticancer Research September 2019, 39 (9) 4925-4931; DOI: https://doi.org/10.21873/anticanres.13680
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Genetic Variants of the IL2 Gene Related to Risk and Survival in Patients With Colorectal Cancer
JAN DIMBERG, LEVAR SHAMOUN, KALLE LANDERHOLM, ROLAND E. ANDERSSON, BLANKA KOLODZIEJ and DICK WÅGSÄTER

Anticancer Research September 2019, 39 (9) 4933-4940; DOI: https://doi.org/10.21873/anticanres.13681
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Characteristics of Breast Cancer Patients Who Refuse Surgery
DAVID J. RESTREPO, ANDREA SISTI, DANIEL BOCZAR, MARIA T. HUAYLLANI, JENNIFER FISHE, EMMANUEL GABRIEL, SARAH A. MCLAUGHLIN, SANJAY BAGARIA, AARON SPAULDING, BRIAN D. RINKER and ANTONIO J. FORTE

Anticancer Research September 2019, 39 (9) 4941-4945; DOI: https://doi.org/10.21873/anticanres.13682
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Tumor-specific Expression of Insulin-like Growth Factor II mRNA-binding Protein 3 Independently Predicts Worse Survival of Patients With Adenocarcinoma of the Ampulla of Vater
HAN GYEOL KIM, MIN-SU PARK, JI-YOUN SUNG, YOUN WHA KIM, HYUN-SOO KIM and KIYONG NA

Anticancer Research September 2019, 39 (9) 4947-4955; DOI: https://doi.org/10.21873/anticanres.13683
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The Influence of Adjuvant Radiotherapy and Single Nucleotide Polymorphisms on Circulating Immune Response Cell Numbers and Phenotypes of Patients With Breast Cancer
NONGNIT LAYTRAGOON LEWIN, THITIYA LUETRAGOON, LEVAR SHAMOUN, DELMY OLIVA, BENGT-ÅKE ANDERSSON, STURE LÖFGREN, LARS ERIK RUTQVIST and FREDDI LEWIN

Anticancer Research September 2019, 39 (9) 4957-4963; DOI: https://doi.org/10.21873/anticanres.13684
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The Normal Epithelium of Crypts Accruing Below Nonpolypoid Adenomas Thrives With Relocated Proliferating Cell-domains and p53-Up-regulated Cells
CARLOS A. RUBIO and PETER T. SCHMIDT

Anticancer Research September 2019, 39 (9) 4965-4970; DOI: https://doi.org/10.21873/anticanres.13685
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Increased Risk of Breast and Uterine Cancer Among Women With Ovarian Granulosa Cell Tumors
DIMITRIOS NASIOUDIS, ELISE WILSON, SPYRIDON A. MASTROYANNIS, GIOVANNI SISTI, ASHLEY F. HAGGERTY, EMILY M. KO and NAWAR A. LATIF

Anticancer Research September 2019, 39 (9) 4971-4975; DOI: https://doi.org/10.21873/anticanres.13686
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Lymph Node Metastases Diagnosed by ¹⁸F-FDG-PET/CT in Esophageal Squamous Cell Cancer Treated With Concurrent Chemoradiotherapy
ICHIRO OGINO, SHIGENOBU WATANABE, TOSHIHIRO MISUMI, MASAHARU HATA and CHIKARA KUNISAKI

Anticancer Research September 2019, 39 (9) 4977-4985; DOI: https://doi.org/10.21873/anticanres.13687
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Previous Immune Checkpoint Inhibitor Treatment to Increase the Efficacy of Docetaxel and Ramucirumab Combination Chemotherapy
DAIJIRO HARADA, KENJI TAKATA, SHUNTA MORI, TOSHIYUKI KOZUKI, YOSHIKA TAKECHI, SATOKO MORIKI, YUMI ASAKURA, TAKAYUKI OHNO and NAOYUKI NOGAMI

Anticancer Research September 2019, 39 (9) 4987-4993; DOI: https://doi.org/10.21873/anticanres.13688
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Tissue Harvesting for Adoptive Tumor Infiltrating Lymphocyte Therapy in Metastatic Melanoma
DOUGLAS ZIPPEL, ORLI FRIEDMAN-ELDAR, SHLOMI RAYMAN, DAVID HAZZAN, AVIRAM NISSAN, GAL SCHTRECHMAN, GAL MARKEL, JACOB SCHACHTER, ORIT ITZHAKI and MICHAL J. BESSER

Anticancer Research September 2019, 39 (9) 4995-5001; DOI: https://doi.org/10.21873/anticanres.13689
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Incorporating Bortezomib in the Management of Plasmablastic Lymphoma
ONYEDIKA UMEANAETO, JOSEPH GAMBOA, JESUS DIAZ, M. NAWAR HAKIM, JAVIER CORRAL, ALEXANDER PHILIPOVSKIY and SUMIT GAUR

Anticancer Research September 2019, 39 (9) 5003-5007; DOI: https://doi.org/10.21873/anticanres.13690
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High Serum Levels of Interleukin-18 Are Associated With Worse Outcomes in Patients With Breast Cancer
NATSUKO INOUE, WEN LI, YUKIE FUJIMOTO, YOSUKE MATSUSHITA, TOYOMASA KATAGIRI, HARUKI OKAMURA and YASUO MIYOSHI

Anticancer Research September 2019, 39 (9) 5009-5018; DOI: https://doi.org/10.21873/anticanres.13691
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Prediction of Portal Vein Thrombosis Following Hepatectomy for Perihilar Cholangiocarcinoma: Efficacy of Postoperative Portal Vein Diameter Ratio and Angle
TSUNEYUKI UCHIDA, YUSUKE YAMAMOTO, TEIICHI SUGIURA, YUKIYASU OKAMURA, TAKAAKI ITO, RYO ASHIDA, KATSUHISA OHGI, TAKESHI ARAMAKI and KATSUHIKO UESAKA

Anticancer Research September 2019, 39 (9) 5019-5026; DOI: https://doi.org/10.21873/anticanres.13692
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Which Factors Affect Survival in Patients With Upper Limb Osteosarcoma?
DAVID J. RESTREPO, MARIA T. HUAYLLANI, DANIEL BOCZAR, ANDREA SISTI, AARON C. SPAULDING, RICKEY E. CARTER, STEVEN L. MORAN, ALEXANDER S. PARKER, GALEN PERDIKIS and ANTONIO J. FORTE

Anticancer Research September 2019, 39 (9) 5027-5031; DOI: https://doi.org/10.21873/anticanres.13693
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Does Robotic Distal Gastrectomy Facilitate Minimally Invasive Surgery for Gastric Cancer?
TAKESHI KUBOTA, DAISUKE ICHIKAWA, TOSHIYUKI KOSUGA, KATSUTOSHI SHODA, SHUHEI KOMATSU, HIROTAKA KONISHI, ATSUSHI SHIOZAKI, HITOSHI FUJIWARA, KAZUMA OKAMOTO and EIGO OTSUJI

Anticancer Research September 2019, 39 (9) 5033-5038; DOI: https://doi.org/10.21873/anticanres.13694
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Efficacy of Adjuvant Chemotherapy According to the Classification of Recurrence Risk Based on Systemic Inflammatory Markers in Patients With Liver Metastases of Colorectal Cancer
MASATSUNE SHIBUTANI, HISASHI NAGAHARA, TATSUNARI FUKUOKA, YASUHITO ISEKI, KOSEI HIRAKAWA and MASAICHI OHIRA

Anticancer Research September 2019, 39 (9) 5039-5045; DOI: https://doi.org/10.21873/anticanres.13695
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Cystic Lateral Neck Lesions: Etiologic and Differential Diagnostic Significance in a Series of 133 Patients
ACHIM FRANZEN, THOMAS GÜNZEL, ANDRE BUCHALI and ANNEKATRIN COORDES

Anticancer Research September 2019, 39 (9) 5047-5052; DOI: https://doi.org/10.21873/anticanres.13696
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Metastatic Bilateral Strumal Carcinoid: A Case Report and Review of the Literature
MARTINA BORGHESE, PAOLA RAZZORE, ANNAMARIA FERRERO, LORENZO DANIELE, LUCA LIBAN MARIANI, LUCA GIUSEPPE SGRO, GIOVANNI DE ROSA and NICOLETTA BIGLIA

Anticancer Research September 2019, 39 (9) 5053-5056; DOI: https://doi.org/10.21873/anticanres.13697
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Feasibility of Identifying Patients at High Risk of Hereditary Gastric Cancer Based on Clinicopathological Variables
SADAAKI NISHIMURA, MASAKAZU YASHIRO, TOMOHIRO SERA, YURIE YAMAMOTO, YUKAKO KUSHITANI, ATSUSHI SUGIMOTO, SHUHEI KUSHIYAMA, KENJI KURODA, SHINGO TOGANO, TOMOHISA OKUNO, TATSURO TAMURA, TAKAHIRO TOYOKAWA, HIROAKI TANAKA, KAZUYA MUGURUMA, KOSEI HIRAKAWA and MASAICHI OHIRA

Anticancer Research September 2019, 39 (9) 5057-5064; DOI: https://doi.org/10.21873/anticanres.13698
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Accelerated Middle Half Body Radiotherapy in Bone Metastases from Prostate Cancer: A Phase I Study (SHARON Project)
ALICE ZAMAGNI, MILLY BUWENGE, GABRIELLA MACCHIA, GIAMBATTISTA SIEPE, SAVINO CILLA, FRANCESCO CELLINI, ALESSANDRA ARCELLI, ELEONORA FARINA, FRANCESCO DEODATO, SILVIA CAMMELLI and ALESSIO G. MORGANTI

Anticancer Research September 2019, 39 (9) 5065-5069; DOI: https://doi.org/10.21873/anticanres.13699
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Diagnostic Accuracy of CYFRA21-1 in the Differential Diagnosis of Pleural Effusions
JAUME TRAPÉ, FRANCESC SANT, JESUS MONTESINOS, ANNA ARNAU, MARIA SALA, OSCAR BERNADICH, ESPERANZA MARTÍN, DAMIA PERICH, JOAN LOPEZ, SANDRA ROS, ENRIQUE ESTEVE-VALVERDE, RAFAEL PÉREZ, CAROLINA GONZÁLEZ-FERNÁNDEZ, JORDI ALIGUE, SILVIA CATOT, MONTSERRAT DOMENECH, DOMINGO RUIZ, MARIONA BONET, RAFAEL MOLINA and JOSEP ORDEIG

Anticancer Research September 2019, 39 (9) 5071-5076; DOI: https://doi.org/10.21873/anticanres.13700
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Performance Status and Its Changes Predict Outcome for Patients With Inoperable Stage III NSCLC Undergoing Multimodal Treatment
LUKAS KÄSMANN, JULIAN TAUGNER, CHUKWUKA EZE, OLARN ROENGVORAPHOJ, MAURICE DANTES, KATHRIN GENNEN, MONIKA KARIN, OLEG PETRUKHNOV, AMANDA TUFMAN, CLAUS BELKA and FARKHAD MANAPOV

Anticancer Research September 2019, 39 (9) 5077-5081; DOI: https://doi.org/10.21873/anticanres.13701
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Keratinocyte Carcinoma and Risk for Another Type of Cancer: Assessment of a Dose-response Relationship
ASHLEY WILSON, JAMES SMALL, CATHERINE FLANAGAN, DAVID PERRY, RICHARD MARCHELL, BRUCE THIERS and ANTHONY J. ALBERG

Anticancer Research September 2019, 39 (9) 5083-5087; DOI: https://doi.org/10.21873/anticanres.13702
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Clinical Impact of FOLFOXIRI Aiming for Conversion Surgery in Unresectable Multiple Colorectal Liver Metastasis
YUJI MORINE, TETSUYA IKEMOTO, SHUICHI IWAHASHI, YU SAITO, SHINICHIRO YAMADA, CHIE TAKASU, JUN HIGASHIJIMA, SATORU IMURA and MITSUO SHIMADA

Anticancer Research September 2019, 39 (9) 5089-5096; DOI: https://doi.org/10.21873/anticanres.13703
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Surgical Strategy for Rectovaginal Fistula After Colorectal Anastomosis at a High-volume Cancer Center According to Image Type and Colonoscopy Findings
KOJI KOMORI, TAKASHI KINOSHITA, TAIHEI OSHIRO, AKIRA OUCHI, SEIJI ITO, TETSUYA ABE, YOSHIKI SENDA, KAZUNARI MISAWA, YUICHI ITO, SEIJI NATSUME, EIJI HIGAKI, MASATAKA OKUNO, TAKAHIRO HOSOI, TAKUYA NAGAO, AINA KUNITOMO, SATOSHI OKI, JIN TAKANO, YASUHITO SUENAGA, SHINGO MAEDA, HIDEYUKI DEI, YOSHIHISA NUMATA and YASUHIRO SHIMIZU

Anticancer Research September 2019, 39 (9) 5097-5103; DOI: https://doi.org/10.21873/anticanres.13704
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Complete Pathological Response Following Radiochemotherapy for Locally Advanced Rectal Cancer: Short and Long-term Outcome
OTHMAN ISKANDER, LISE COURTOT, NICOLAS TABCHOURI, ALICE ARTUS, NICOLAS MICHOT, OLIVIER MULLER, URS PABST-GIGER, PASCAL BOURLIER, AURORE KRAEMER-BUCUR, THIERRY LECOMTE, SERGE GUYETANT, SOPHIE CHAPET, GILLES CALAIS, EPHREM SALAMÉ and MEHDI OUAÏSSI

Anticancer Research September 2019, 39 (9) 5105-5113; DOI: https://doi.org/10.21873/anticanres.13705
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Soluble Interleukin-2 Receptor Level at Diagnosis Predicts Prognosis of Patients With Follicular Lymphoma Irrespective of Initial Management Strategy
MASAHIDE YAMAMOTO, KEISUKE TANAKA, YOSHIHIRO UMEZAWA, TOSHIKAGE NAGAO, SHIGEO TOYOTA and OSAMU MIURA

Anticancer Research September 2019, 39 (9) 5115-5122; DOI: https://doi.org/10.21873/anticanres.13706
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A Randomized Phase III Trial on the Role of Esophagectomy in Complete Responders to Preoperative Chemoradiotherapy for Esophageal Squamous Cell Carcinoma (ESOPRESSO)
SOOK RYUN PARK, DOK HYUN YOON, JONG HOON KIM, YONG-HEE KIM, HYEONG RYUL KIM, HYUN JOO LEE, HWOON-YONG JUNG, GIN-HYUG LEE, HO JUNE SONG, DO HOON KIM, KEE DON CHOI, JEONG HOON LEE, JI YONG AHN, JIN-SOOK RYU, KYUNG-JA CHO and SUNG-BAE KIM

Anticancer Research September 2019, 39 (9) 5123-5133; DOI: https://doi.org/10.21873/anticanres.13707
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Overall Survival of Patients With Locoregional and Metastatic Breast Cancer: Is the Influence of Baseline Characteristics the Same?
INÊS GOMES, PEDRO AGUIAR, ANA MIRANDA and CARLA NUNES

Anticancer Research September 2019, 39 (9) 5135-5142; DOI: https://doi.org/10.21873/anticanres.13708
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Assessment of Outcome of Hepatic Resection for Extremely Elderly Patients With a Hepatic Malignancy
TAKASHI HORIUCHI, KOICHIRO HARUKI, HIROAKI SHIBA, TARO SAKAMOTO, NOBUHIRO SAITO, YOSHIHIRO SHIRAI, RYOTA IWASE, YUKI FUJIWARA and KATSUHIKO YANAGA

Anticancer Research September 2019, 39 (9) 5143-5148; DOI: https://doi.org/10.21873/anticanres.13709
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Impact of Relative Dose Intensity of Early-phase Lenvatinib Treatment on Therapeutic Response in Hepatocellular Carcinoma
AYA TAKAHASHI, MICHIHISA MORIGUCHI, YUYA SEKO, HIROKI ISHIKAWA, TAKAHARU YO, HIROYUKI KIMURA, HIDEKI FUJII, TOSHIHIDE SHIMA, YASUHIDE MITSUMOTO, HIROSHI ISHIBA, HIDETAKA TAKASHIMA, YASUYUKI NAGAO, MASAYASU JO, MASAHIRO ARAI, TASUKU HARA, AKIRA OKAJIMA, AKIRA MURAMATSU, ATSUHIRO MORITA, NAOMI YOSHINAMI, TOMOKI NAKAJIMA, HIRONORI MITSUYOSHI, ATSUSHI UMEMURA, TAICHIRO NISHIKAWA, KANJI YAMAGUCHI and YOSHITO ITOH

Anticancer Research September 2019, 39 (9) 5149-5156; DOI: https://doi.org/10.21873/anticanres.13710
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Change in PMI During Neoadjuvant Therapy Is a Predictive Prognostic Marker in Rectal Cancer
TATSUNARI FUKUOKA, KIYOSHI MAEDA, HISASHI NAGAHARA, MASATSUNE SHIBUTANI, YASUHITO ISEKI, SHINJI MATSUTANI, KOSEI HIRAKAWA and MASAICHI OHIRA

Anticancer Research September 2019, 39 (9) 5157-5163; DOI: https://doi.org/10.21873/anticanres.13711
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Daratumumab Monotherapy in Heavily Pretreated Asian Patients With Relapsed and Refractory Multiple Myeloma: A Real-world Experience
JA MIN BYUN, SUNG-SOO YOON, YOUNGIL KOH, INHO KIM, JAEMIN JO, HYUNKYUNG PARK, JEONG-OK LEE and JIYUN LEE

Anticancer Research September 2019, 39 (9) 5165-5170; DOI: https://doi.org/10.21873/anticanres.13712
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Pretreatment Serum Levels of Soluble Cytokeratin Fragments (Cyfra 21-1, TPS, MonoTotal) in Relation to Clinical and Pathobiological Aspects of Head and Neck Squamous Cell Carcinomas
DAVID KALFERT, JAROSLAV LUDVIK, RADEK KUCERA, ONDREJ TOPOLCAN, PETR CELAKOVSKY, MARTIN PESTA, IVANA KHOLOVA, JAN PLZAK and MARIE LUDVIKOVA

Anticancer Research September 2019, 39 (9) 5171-5177; DOI: https://doi.org/10.21873/anticanres.13713
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The Role of Dimethoate and UV-B on Skin of Wistar Rats
TANIA RITA MORENO DE OLIVEIRA FERNANDES, CELINA TIZUKO FUJIYAMA OSHIMA, LEONARDO CARDILI, DANIEL ARAKI RIBEIRO, MARCELO SOUZA SILVA, JULIANA PEDROSA KORINFSKY and HÉLIO PLAPLER

Anticancer Research September 2019, 39 (9) 5179-5184; DOI: https://doi.org/10.21873/anticanres.13714
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Schwannoma of Foot and Ankle: Seven Case Reports and Literature Review
XINGPEI HAO, DAVID LEVINE, JOON YIM, CHENFENG QI, LEE FIRESTONE, IAN BEISER, ENZO LEONE, KIRK WOELFFER and GENE MIRKIN

Anticancer Research September 2019, 39 (9) 5185-5194; DOI: https://doi.org/10.21873/anticanres.13715
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Plasma Levels of Soluble PD-L1 Correlate With Tumor Regression in Patients With Lung and Gastric Cancer Treated With Immune Checkpoint Inhibitors
KIYOHIRO ANDO, KAZUYUKI HAMADA, MAKOTO WATANABE, RYOTARO OHKUMA, MIDORI SHIDA, RIE ONOUE, YUTARO KUBOTA, HIROTO MATSUI, TOMOYUKI ISHIGURO, YUYA HIRASAWA, HIROTSUGU ARIIZUMI, JUNJI TSURUTANI, KIYOSHI YOSHIMURA, TAKUYA TSUNODA, SHINICHI KOBAYASHI and SATOSHI WADA

Anticancer Research September 2019, 39 (9) 5195-5201; DOI: https://doi.org/10.21873/anticanres.13716
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Outcome of Pediatric Acute Lymphoblastic Leukemia: Sixty Years of Progress
EWA DEMIDOWICZ, MONIKA POGORZAŁA, MONIKA ŁĘCKA, HANNA ŻOŁNOWSKA, AGATA MARJAŃSKA, MAŁGORZATA KUBICKA, BEATA KURYŁO-RAFIŃSKA, KRZYSZTOF CZYŻEWSKI, ROBERT DĘBSKI, ANDRZEJ KOŁTAN, MONIKA RICHERT-PRZYGOŃSKA and JAN STYCZYŃSKI

Anticancer Research September 2019, 39 (9) 5203-5207; DOI: https://doi.org/10.21873/anticanres.13717
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Prevention of Anastomotic Leakage in Ovarian Cancer Debulking Surgery and Its Impact on Overall Survival
ARNE KOSCIELNY, ANNA KO, EVA K. EGGER, WALTER KUHN, JÖRG C. KALFF and MIGNON-DENISE KEYVER-PAIK

Anticancer Research September 2019, 39 (9) 5209-5218; DOI: https://doi.org/10.21873/anticanres.13718
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Determination of Mesothelin Levels in Pleural Effusion Does Not Help Predict Survival of Patients With Malignant Pleural Mesothelioma
VINCENZO FONTANA, MARIA PIA PISTILLO, ANTONELLA VIGANI, PIER ALDO CANESSA, GIOVANNI BERISSO, UGO GIANNONI, PAOLA FERRO, MARIA CRISTIANA FRANCESCHINI, ROBERTA CAROSIO, MARIKA TONARELLI, CRISTIANA ROSSI, PAOLO DESSANTI and SILVIO RONCELLA

Anticancer Research September 2019, 39 (9) 5219-5223; DOI: https://doi.org/10.21873/anticanres.13719

Errata

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Errata
Anticancer Research September 2019, 39 (9) 5225;
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Errata
Anticancer Research September 2019, 39 (9) 5225;
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BOOK REVIEWS

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Book Reviews
Anticancer Research September 2019, 39 (9) 5227;
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Molecular and Cellular Biology of Viruses. 1st Edition
Anticancer Research September 2019, 39 (9) 5227;
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External Beam Therapy. Third Edition
Anticancer Research September 2019, 39 (9) 5227;
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Cancer-related Breakthrough Pain. Third Edition
Anticancer Research September 2019, 39 (9) 5227;

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Anticancer Research September 2019, 39 (9) 5229;

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