Table of Contents

Clinical Studies

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  Improved Survival With Higher Pre-diagnosis Cardiorespiratory Fitness in Men Who Developed Digestive System Cancers: A Prospective Pilot Study

  BARUCH VAINSHELBOIM, ZHONGMING CHEN and JONATHAN MYERS

  Anticancer Research October 2019, 39 (10) 5551-5557; DOI: https://doi.org/10.21873/anticanres.13748
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  Sunitinib First-line Treatment in Metastatic Renal Cell Carcinoma: Costs and Effects

  RIIKKA-LIISA VUORINEN, NIINA PAUNU, TAINA TURPEENNIEMI-HUJANEN, TAINA REUNAMO, ANTTI JEKUNEN, VESA KATAJA, HARRI SINTONEN, TIMO PURMONEN and PIRKKO-LIISA KELLOKUMPU-LEHTINEN

  Anticancer Research October 2019, 39 (10) 5559-5564; DOI: https://doi.org/10.21873/anticanres.13749
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  Impact of Extravasated Platelet Activation and Podoplanin-positive Cancer-associated Fibroblasts in Pancreatic Cancer Stroma

  TOMOHARU MIYASHITA, HIDEHIRO TAJIMA, RYOSUKE GABATA, MITSUYOSHI OKAZAKI, HIROYUKI SHIMBASHI, YOSHINAO OHBATAKE, KOICHI OKAMOTO, SINICHI NAKANUMA, SEISHO SAKAI, ISAMU MAKINO, JUN KINOSHITA, HIRONORI HAYASHI, KEISHI NAKAMURA, HIROYUKI TAKAMURA, ITASU NINOMIYA, SACHIO FUSHIDA, JOHN W. HARMON and TETSUO OHTA

  Anticancer Research October 2019, 39 (10) 5565-5572; DOI: https://doi.org/10.21873/anticanres.13750
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  Decreased H3K27me3 Expression Is Associated With Merkel Cell Polyomavirus-negative Merkel Cell Carcinoma, Especially Combined With Cutaneous Squamous Cell Carcinoma

  MICHIKO MATSUSHITA, TAKESHI IWASAKI, LUSI OKA WARDHANI, SATOSHI KUWAMOTO, DAISUKE NONAKA, KEIKO NAGATA, MASAKO KATO, YUKISATO KITAMURA and KAZUHIKO HAYASHI

  Anticancer Research October 2019, 39 (10) 5573-5579; DOI: https://doi.org/10.21873/anticanres.13751
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  Clinical Evaluation of Dynamic Monitoring of Neutrophil–to–lymphocyte and Platelet–to–lymphocyte Ratios in Primary Endocrine Therapy for Advanced Breast Cancer

  KOJI TAKADA, SHINICHIRO KASHIWAGI, YUKA ASANO, WATARU GOTO, KATSUYUKI TAKAHASHI, MASATSUNE SHIBUTANI, RYOSUKE AMANO, TSUTOMU TAKASHIMA, SHUHEI TOMITA, KOSEI HIRAKAWA and MASAICHI OHIRA

  Anticancer Research October 2019, 39 (10) 5581-5588; DOI: https://doi.org/10.21873/anticanres.13752
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  Age as a Predictor of Treatment Outcome in Metastatic Testicular Germ Cell Tumors

  ANGELIKA TERBUCH, FLORIAN POSCH, THOMAS BAUERNHOFER, MARTIN PICHLER, HEIDI PEINSITH, JOANNA SZKANDERA, JAKOB RIEDL, GEORG C. HUTTERER, KARL PUMMER, RICHARD PARTL, KARIN S. KAPP, HERBERT STÖGER, MICHAEL STOTZ and ARMIN GERGER

  Anticancer Research October 2019, 39 (10) 5589-5596; DOI: https://doi.org/10.21873/anticanres.13753
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  Bilateral Asynchronous Renal Cell Carcinoma With Lung Metastases: A Case Report of a Patient Treated Solely With High-dose Intravenous and Subcutaneous Viscum album Extract for a Second Renal Lesion

  MARÍA REYNEL, YVÁN VILLEGAS, HELMUT KIENE, PAUL G. WERTHMANN and GUNVER S. KIENLE

  Anticancer Research October 2019, 39 (10) 5597-5604; DOI: https://doi.org/10.21873/anticanres.13754
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  The Clinical Outcomes of Hemicortical Extracorporeal Irradiated Autologous Bone Graft After Tumor Resection of Bone and Soft Tissue Sarcoma

  TOMOKI NAKAMURA, TOMOHIRO FUJIWARA, YUSUKE TSUDA, ADESEGUN ABUDU, YOSHIHITO NOMOTO, AKINORI TAKADA, YUTAKA TOYOMASU, TOMOHITO HAGI, KUNIHIRO ASANUMA and AKIHIRO SUDO

  Anticancer Research October 2019, 39 (10) 5605-5610; DOI: https://doi.org/10.21873/anticanres.13755
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  Factors that Influence Chemotherapy Treatment Rate in Patients With Upper Limb Osteosarcoma

  DAVID J. RESTREPO, MARIA T. HUAYLLANI, DANIEL BOCZAR, ANDREA SISTI, AARON C. SPAULDING, STEVEN L. MORAN, THIHA AUNG, SANJAY BAGARIA, OSCAR J. MANRIQUE and ANTONIO J. FORTE

  Anticancer Research October 2019, 39 (10) 5611-5615; DOI: https://doi.org/10.21873/anticanres.13756
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  Incidence and Pattern of Spread of Lymph Node Metastasis in Patients With Low-grade Serous Ovarian Cancer

  MOHAMED WAFA, ELENA I. BRAICU, MUSTAFA Z. MUALLEM, ROLF RICHTER, ELIANE TAUBE, JALID SEHOULI and JACEK P. GRABOWSKI

  Anticancer Research October 2019, 39 (10) 5617-5621; DOI: https://doi.org/10.21873/anticanres.13757
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  Cyclo-oxygenase-2 Expression Is Associated With Lymph Node Metastasis in Oropharyngeal Squamous Cell Carcinoma Under the New TNM Classification

  MARIKO SEKIMIZU, HIROYUKI OZAWA, SHIN SAITO, YUICHI IKARI, NANA NAKAHARA, SHINTARO NAKAMURA, KEISUKE YOSHIHAMA, FUMIHIRO ITO, YOSHIHIRO WATANABE, YORIHISA IMANISHI, KAORI KAMEYAMA and KAORU OGAWA

  Anticancer Research October 2019, 39 (10) 5623-5630; DOI: https://doi.org/10.21873/anticanres.13758
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  Pelvic Exenteration as Potential Cure and Symptom Relief in Advanced and Recurrent Gynaecological Cancer

  SHU SOEDA, SHIGENORI FURUKAWA, TETSU SATO, MAKIKO UEDA, NORIHIRO KAMO, YUTA ENDO, MANABU KOJIMA, SHINZI NOMURA, MASAO KATAOKA, SHOTARO FUJITA, HISAHITO ENDO, TOSHIFUMI TAKAHASHI, TAKAFUMI WATANABE, HIDEKAZU YAMADA and KEIYA FUJIMORI

  Anticancer Research October 2019, 39 (10) 5631-5637; DOI: https://doi.org/10.21873/anticanres.13759
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  Diabetes Mellitus and/or Nonalcoholic Steatohepatitis-related Hepatocellular Carcinoma Showed Favorable Surgical Outcomes After Hepatectomy

  JING LIANG, SHUN-ICHI ARIIZUMI, MASAYUKI NAKANO and MASAKAZU YAMAMOTO

  Anticancer Research October 2019, 39 (10) 5639-5643; DOI: https://doi.org/10.21873/anticanres.13760
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  The Predictive Role of Primary Tumour Sidedness in Metastatic Colorectal Cancer Treated With Targeted Agents

  ONDREJ FIALA, PAVEL OSTASOV, PETR HOSEK, ONDREJ SOREJS, VACLAV LISKA, TOMAS BUCHLER, ALEXANDR POPRACH, RADEK KUCERA, ONDREJ TOPOLCAN, JAN SUSTR, MONIKA SEDIVCOVA and JINDRICH FINEK

  Anticancer Research October 2019, 39 (10) 5645-5652; DOI: https://doi.org/10.21873/anticanres.13761
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  A Single-centre, Retrospective, Observational Analysis of Fulvestrant for Recurrent/metastatic Breast Cancer According to Metastatic Site

  HIROMI OZAWA, ATSUSHI SATA, REIKO FUKUI, AYAKO BUN, TOMOKO HIGUCHI, YUKIE FUJIMOTO, YOSHIMASA MIYAGAWA, MICHIKO IMAMURA and YASUO MIYOSHI

  Anticancer Research October 2019, 39 (10) 5653-5662; DOI: https://doi.org/10.21873/anticanres.13762
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  Osteosarcoma of the Upper Extremities: A National Analysis of the US Population

  MARIA T. HUAYLLANI, DAVID J. RESTREPO, DANIEL BOCZAR, ANDREA SISTI, AARON C. SPAULDING, ALEXANDER S. PARKER, RACHEL SARABIA-ESTRADA, HUGO GUERRERO-CAZARES, STEVEN L. MORAN and ANTONIO J. FORTE

  Anticancer Research October 2019, 39 (10) 5663-5668; DOI: https://doi.org/10.21873/anticanres.13763
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  Survival Disparities in Male Patients With Breast Cancer

  DAVID J. RESTREPO, DANIEL BOCZAR, MARIA T. HUAYLLANI, ANDREA SISTI, SARAH A. MCLAUGHLIN, AARON SPAULDING, ALEXANDER S. PARKER, RICKEY E. CARTER, AARON L. LEPPIN and ANTONIO J. FORTE

  Anticancer Research October 2019, 39 (10) 5669-5674; DOI: https://doi.org/10.21873/anticanres.13764
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  Neutrophil–to–lymphocyte Ratio and Use of Antibiotics Associated With Prognosis in Esophageal Squamous Cell Carcinoma Patients Receiving Immune Checkpoint Inhibitors

  JHE-CYUAN GUO, CHIA-CHI LIN, CHEN-YUAN LIN, MIN-SHU HSIEH, HUNG-YANG KUO, MING-YU LIEN, YU-YUN SHAO, TA-CHEN HUANG and CHIH-HUNG HSU

  Anticancer Research October 2019, 39 (10) 5675-5682; DOI: https://doi.org/10.21873/anticanres.13765
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  Comparison of the Utilities of Cryobiopsy and Forceps Biopsy for Peripheral Lung Cancer

  SHINGO NASU, NORIO OKAMOTO, HIDEKAZU SUZUKI, TAKAYUKI SHIROYAMA, AYAKO TANAKA, YUMIKO SAMEJIMA, TOMOHIRO KANAI, YOSHIMI NODA, SATOMU MORITA, NAOKO MORISHITA, KAYO UEDA, KUNIMITSU KAWAHARA and TOMONORI HIRASHIMA

  Anticancer Research October 2019, 39 (10) 5683-5688; DOI: https://doi.org/10.21873/anticanres.13766
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  Diameter of External Carotid Arteries in Patients With Mandibular Osteoradionecrosis

  NAOYA ISHIBASHI, TOSHIYA MAEBAYASHI, TAKUYA AIZAWA, MASAKUNI SAKAGUCHI and MASAHIRO OKADA

  Anticancer Research October 2019, 39 (10) 5689-5693; DOI: https://doi.org/10.21873/anticanres.13767
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  Conversion Hepatectomy for Huge Hepatocellular Carcinoma With Arterioportal Shunt After Chemoembolization and Lenvatinib Therapy

  NOBUTAKA SATO, TORU BEPPU, KOICHI KINOSHITA, HIDEAKI YUKI, KOICHI SUYAMA, SUGURU CHIYONAGA, TOSHIHIKO MOTOHARA, YOSHIHIKO KOMOHARA, AKIO HARA and SHINICHI AKAHOSHI

  Anticancer Research October 2019, 39 (10) 5695-5701; DOI: https://doi.org/10.21873/anticanres.13768
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  The Role of Metoprolol and Enalapril in the Prevention of Doxorubicin-induced Cardiotoxicity in Lymphoma Patients

  PETER GEORGAKOPOULOS, MICHAEL KYRIAKIDIS, ANASTASIA PERPINIA, APOSTOLOS KARAVIDAS, STELIOS ZIMERAS, NIKOLAOS MAMALIS, MAROUSA KOUVELA and ANDRIANI CHARPIDOU

  Anticancer Research October 2019, 39 (10) 5703-5707; DOI: https://doi.org/10.21873/anticanres.13769
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  Changing Trends in Mastectomy and Breast Reconstruction. Analysis of a Single-institution Experience Between 2004-2016

  TOMMASO SUSINI, IRENE RENDA, MILO GIANI, ARIANNA VALLARIO, JACOPO NORI, ERMANNO VANZI, ALESSANDRO INNOCENTI, GIULIA LO RUSSO and SIMONETTA BIANCHI

  Anticancer Research October 2019, 39 (10) 5709-5714; DOI: https://doi.org/10.21873/anticanres.13770
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  Clinical Significance of PRKCI Gene Expression in Cancerous Tissue in Patients With Gastric Cancer

  ITARU HASHIMOTO, KENTARO SAKAMAKI, NAOHIDE OUE, YAYOI KIMURA, YUKIHIKO HIROSHIMA, KENTARO HARA, YUKIO MAEZAWA, KAZUKI KANO, TORU AOYAMA, TAKANOBU YAMADA, NAOTO YAMAMOTO, TAKASHI OGATA, HIROYUKI ITO, MANABU SHIOZAWA, SOICHIRO MORINAGA, YASUSHI RINO, WATARU YASUI, MUNETAKA MASUDA, YOHEI MIYAGI and TAKASHI OSHIMA

  Anticancer Research October 2019, 39 (10) 5715-5720; DOI: https://doi.org/10.21873/anticanres.13771
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  Identification of the Risk Factors for Recurrence of Stage III Colorectal Cancer

  KAI NEKI, KEN ETO, MAKOTO KOSUGE, MASAHISA OHKUMA, DAISUKE ITO, YASUHIRO TAKEDA, SAORI YATABE, HIROSHI SUGANO and KATSUHIKO YANAGA

  Anticancer Research October 2019, 39 (10) 5721-5724; DOI: https://doi.org/10.21873/anticanres.13772
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  Chemotherapy-associated Acute Exacerbation of Interstitial Lung Disease Shortens Survival Especially in Small Cell Lung Cancer

  SATOSHI NAKAO, KAKUHIRO YAMAGUCHI, SHINJIRO SAKAMOTO, YASUSHI HORIMASU, TAKESHI MASUDA, SHINTARO MIYAMOTO, TAKU NAKASHIMA, HIROSHI IWAMOTO, KAZUNORI FUJITAKA, HIRONOBU HAMADA and NOBORU HATTORI

  Anticancer Research October 2019, 39 (10) 5725-5731; DOI: https://doi.org/10.21873/anticanres.13773
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  Patterns of Care After Surgery for Elderly Patients With Malignant Brain Tumors: Data from the National Health Insurance Service in South Korea

  HYEON KANG KOH, HYEONGSU KIM and SEMIE HONG

  Anticancer Research October 2019, 39 (10) 5733-5739; DOI: https://doi.org/10.21873/anticanres.13774
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  Cardiovascular Risk Factors and Timing of Anthracyclines and Trastuzumab Cardiac Toxicity

  MARIA LAURA CANALE, ANDREA CAMERINI, ALDA HUQI, ALESSIO LILLI, IRMA BISCEGLIA, IRIS PARRINI, CHIARA LESTUZZI, JACOPO DEL MEGLIO, SARA DONATI, ELIO VENTURINI, ALESSANDRO SGAMBATO, LUIGI TARANTINI, DOMENICO AMOROSO and GIANCARLO CASOLO

  Anticancer Research October 2019, 39 (10) 5741-5745; DOI: https://doi.org/10.21873/anticanres.13775
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  Long-term Outcome of 181 Patients With Liposarcomas of the Extremity and Truncal Wall

  OLE GOERTZ, ANDREAS PIEPER, HENRIK LAUER, INGO STRICKER, MEHRAN DADRAS, BJÖRN BEHR, MARCUS LEHNHARDT and KAMRAN HARATI

  Anticancer Research October 2019, 39 (10) 5747-5753; DOI: https://doi.org/10.21873/anticanres.13776
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  Risk Factors for Deterioration of Remnant Liver Function After Hepatic Resection for Hepatocellular Carcinoma

  RUI MARUKUCHI, KENEI FURUKAWA, RYOTA IWASE, JUNGO YASUDA, HIRONORI SHIOZAKI, SHINJI ONDA, TAKESHI GOCHO, HIROAKI SHIBA and KATSUHIKO YANAGA

  Anticancer Research October 2019, 39 (10) 5755-5760; DOI: https://doi.org/10.21873/anticanres.13777
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  Clinical Significance of Intraoperative Colonoscopy for Anastomotic Assessment in Rectal Cancer Surgery

  NAOKI SHIBUYA, TAKERU MATSUDA, KIMIHIRO YAMASHITA, HIROSHI HASEGAWA, MASASHI YAMAMOTO, SHINGO KANAJI, TARO OSHIKIRI, TETSU NAKAMURA, SATOSHI SUZUKI and YOSHIHIRO KAKEJI

  Anticancer Research October 2019, 39 (10) 5761-5765; DOI: https://doi.org/10.21873/anticanres.13778
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  Treatment Strategy for Rectal Cancer Patients With Inguinal Lymph Node Metastasis

  KOJI UETA, TAKERU MATSUDA, KIMIHIRO YAMASHITA, HIROSHI HASEGAWA, JUNKO MUKOHYAMA, MASASHI YAMAMOTO, YOSHIKO MATSUDA, SHINGO KANAJI, TARO OSHIKIRI, TETSU NAKAMURA, SATOSHI SUZUKI and YOSHIHIRO KAKEJI

  Anticancer Research October 2019, 39 (10) 5767-5772; DOI: https://doi.org/10.21873/anticanres.13779
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  Serum γ-Glutamyltransferase as a Prognostic Biomarker in Metastatic Castration-resistant Prostate Cancer Treated With Enzalutamide

  KOSUKE TAKEMURA, MASAYA ITO, YASUKAZU NAKANISHI, MADOKA KATAOKA, KAZUMASA SAKAMOTO, HIROAKI SUZUKI, KEN-ICHI TOBISU and FUMITAKA KOGA

  Anticancer Research October 2019, 39 (10) 5773-5780; DOI: https://doi.org/10.21873/anticanres.13780
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  Neoadjuvant Chemotherapy Enhances Local Postoperative Histopathological Tumour Stage in Borderline Resectable Pancreatic Cancer – A Matched-Pair Analysis

  LEA TIMMERMANN, NATHALIE ROSUMECK, FRITZ KLEIN, JOHANN PRATSCHKE, UWE PELZER, MARCUS BAHRA and THOMAS MALINKA

  Anticancer Research October 2019, 39 (10) 5781-5787; DOI: https://doi.org/10.21873/anticanres.13781
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  Clinicopathological Features, Surgical Outcomes, Oncogenic Status and PD-L1 Expression of Pulmonary Pleomorphic Carcinoma

  KEITA NAKANISHI, NORIAKI SAKAKURA, TAKUYA MATSUI, HARUSHI UENO, TAKEO NAKADA, YUKO OYA, JUNICHI SHIMIZU, TOYOAKI HIDA, WAKI HOSODA and HIROAKI KURODA

  Anticancer Research October 2019, 39 (10) 5789-5795; DOI: https://doi.org/10.21873/anticanres.13782
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  Concomitant Treatment of Malignant Brain Tumours With CBD – A Case Series and Review of the Literature

  RUDOLF LIKAR, MARKUS KOESTENBERGER, MARTIN STULTSCHNIG and GERHARD NAHLER

  Anticancer Research October 2019, 39 (10) 5797-5801; DOI: https://doi.org/10.21873/anticanres.13783
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  Risk Factors for Poor Survival in Metastatic Castration-resistant Prostate Cancer Treated With Cabazitaxel in Japan

  SHOTARO YASUOKA, TAKESHI YUASA, MASAHIRO OGAWA, YOSHINOBU KOMAI, NOBORU NUMAO, SHINYA YAMAMOTO, YUKIHIRO KONDO and JUNJI YONESE

  Anticancer Research October 2019, 39 (10) 5803-5809; DOI: https://doi.org/10.21873/anticanres.13784
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  Clinical Outcomes and the Role of Adjuvant Concurrent Chemoradiation Therapy in D2-resected LN-positive Young Patients (≤45 Years) With Gastric Cancer

  JEONG IL YU, DO HOON LIM, JEEYUN LEE, WON KI KANG, SE HOON PARK, JOON OH PARK, HO YEONG LIM, SEUNG TAE KIM, SUNG KIM, TAE SUNG SOHN, JUN HO LEE, JI YEONG AN, MIN GEW CHOI, JAE MOON BAE, HYE SEUNG KIM and SOOHYUN AHN

  Anticancer Research October 2019, 39 (10) 5811-5820; DOI: https://doi.org/10.21873/anticanres.13785
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  The Anatomical Pattern of the Proximal Jejunal Vein as a Prognostic Factor in Patients With Pancreatic Head Cancer Treated With Preoperative Chemoradiation Therapy

  SADAAKI NISHIMURA, HIDENORI TAKAHASHI, HIROFUMI AKITA, KEI ASUKAI, SHINICHIRO HASEGAWA, DAISAKU YAMADA, HIROSHI WADA, HISASHI HARA, NAOKI SHINNO, HAJIME USHIGOME, NAOTSUGU HARAGUCHI, KEIJIRO SUGIMURA, KAZUYOSHI YAMAMOTO, JUNICHI NISHIMURA, MASAYOSHI YASUI, TAKESHI OMORI, HIROSHI MIYATA, MASAYUKI OHUE, MASAHIKO YANO, MASATO SAKON and OSAMU ISHIKAWA

  Anticancer Research October 2019, 39 (10) 5821-5830; DOI: https://doi.org/10.21873/anticanres.13786
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  ABSTRACTS OF THE 2019 SUMMIT ON NATIONAL AND GLOBAL CANCER HEALTH DISPARITIES (SCHD19)

  Anticancer Research October 2019, 39 (10) 5831-5839; DOI: https://doi.org/10.21873/anticanres.13787
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  ABSTRACTS OF THE 7^TH INTERNATIONAL CONFERENCE ON ADVANCES IN HEMATOLOGY AND ONCOLOGY (ICAHO2019)

  Anticancer Research October 2019, 39 (10) 5841-5851; DOI: https://doi.org/10.21873/anticanres.13788