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Research ArticleClinical Studies

Diagnostic Utility of Prostein, Uroplakin II and SATB2 for Diagnosing Carcinoma of Unknown Primary Origin: A Systematic Immunohistochemical Profiling

KUNIO MOCHIZUKI, MASATAKA KAWAI, TORU ODATE, IPPEI TAHARA, TOMOHIRO INOUE, KAZUNARI KASAI, TADAO NAKAZAWA, RYOHEI KATOH and TETSUO KONDO
Anticancer Research August 2018, 38 (8) 4759-4766; DOI: https://doi.org/10.21873/anticanres.12784
KUNIO MOCHIZUKI
Department of Pathology, School of Medicine, University of Yamanashi, Chuo, Japan
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  • For correspondence: kuniom{at}yamanashi.ac.jp
MASATAKA KAWAI
Department of Pathology, School of Medicine, University of Yamanashi, Chuo, Japan
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TORU ODATE
Department of Pathology, School of Medicine, University of Yamanashi, Chuo, Japan
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IPPEI TAHARA
Department of Pathology, School of Medicine, University of Yamanashi, Chuo, Japan
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TOMOHIRO INOUE
Department of Pathology, School of Medicine, University of Yamanashi, Chuo, Japan
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KAZUNARI KASAI
Department of Pathology, School of Medicine, University of Yamanashi, Chuo, Japan
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TADAO NAKAZAWA
Department of Pathology, School of Medicine, University of Yamanashi, Chuo, Japan
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RYOHEI KATOH
Department of Pathology, School of Medicine, University of Yamanashi, Chuo, Japan
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TETSUO KONDO
Department of Pathology, School of Medicine, University of Yamanashi, Chuo, Japan
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    Figure 1.

    Representative immunohistochemical images of prostein in carcinoma tissues. Acinar adenocarcinoma of the prostate (A) which exhibits prostein immunoreactivity (B) in the cytoplasm with Golgi-type distribution. Invasive carcinoma of no special type of the breast (C) which exhibits prostein immunoreactivity (D) in the cytoplasm. Original magnification ×200.

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    Figure 2.

    Representative immunohistochemical images of uroplakin II in carcinoma tissues. Infiltrating urothelial carcinoma of the urinary bladder (A) which exhibits uroplakin II immunoreactivity (B) in the cytoplasm. Classical hepatocellular carcinoma of the liver (C) which exhibits uroplakin II immunoreactivity (D) in the intracytoplasmic hyaline bodies. Original magnification ×200 (A and B); ×400 (C and D).

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    Figure 3.

    Representative immunohistochemical images of SATB2 in carcinoma tissues. Ordinary adenocarcinoma of the colon (A) which exhibits SATB2 immunoreactivity (B) in the nucleus. Tubular adenocarcinoma of the stomach (C) which exhibits SATB2 immunoreactivity (D) in the nucleus. Original magnification ×200.

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Anticancer Research
Vol. 38, Issue 8
August 2018
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Diagnostic Utility of Prostein, Uroplakin II and SATB2 for Diagnosing Carcinoma of Unknown Primary Origin: A Systematic Immunohistochemical Profiling
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Diagnostic Utility of Prostein, Uroplakin II and SATB2 for Diagnosing Carcinoma of Unknown Primary Origin: A Systematic Immunohistochemical Profiling
KUNIO MOCHIZUKI, MASATAKA KAWAI, TORU ODATE, IPPEI TAHARA, TOMOHIRO INOUE, KAZUNARI KASAI, TADAO NAKAZAWA, RYOHEI KATOH, TETSUO KONDO
Anticancer Research Aug 2018, 38 (8) 4759-4766; DOI: 10.21873/anticanres.12784

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Diagnostic Utility of Prostein, Uroplakin II and SATB2 for Diagnosing Carcinoma of Unknown Primary Origin: A Systematic Immunohistochemical Profiling
KUNIO MOCHIZUKI, MASATAKA KAWAI, TORU ODATE, IPPEI TAHARA, TOMOHIRO INOUE, KAZUNARI KASAI, TADAO NAKAZAWA, RYOHEI KATOH, TETSUO KONDO
Anticancer Research Aug 2018, 38 (8) 4759-4766; DOI: 10.21873/anticanres.12784
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Keywords

  • Prostein
  • uroplakin II
  • SATB2
  • immunohistochemistry
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