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Research ArticleClinical Studies

Unusual Papillary Squamous Cell Carcinoma of the Tip of Tongue Presenting in a Patient Status Post Heart Transplant

FARAJ ALOTAIBY, FENGLIN SONG, BRIAN J. BOYCE, DENGFENG CAO, YULIN ZHAO and JINPING LAI
Anticancer Research July 2018, 38 (7) 4203-4206; DOI: https://doi.org/10.21873/anticanres.12715
FARAJ ALOTAIBY
1Department of Oral and Maxillofacial Pathology, University of Florida College of Dentistry, Gainesville, FL, U.S.A.
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FENGLIN SONG
2Division of Cardiac Surgery, Department of Surgery, Second Xiangya Hospital, Central South University, Changsha, P.R. China
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BRIAN J. BOYCE
3Department of Otolaryngology-Head and Neck Surgery, University of Florida College of Medicine, Gainesville, FL, U.S.A.
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DENGFENG CAO
4Department of Pathology, Immunology, and Laboratory Medicine, Washington University in Saint Louis, St. Louis, MO, U.S.A.
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YULIN ZHAO
5Department of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, P.R. China
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  • For correspondence: jinpinglai{at}ufl.edu zhaoyulinmail{at}163.com
JINPING LAI
6Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL, U.S.A.
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  • For correspondence: jinpinglai{at}ufl.edu zhaoyulinmail{at}163.com
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    Figure 1.

    Computed tomography (CT) scans showing a mass (arrows) with focal enhanced rim at the tip of the tongue (A, sagittal; B, axial).

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    Figure 2.

    Histology and immunoreactivity of the PSCC. A-C: H&E stain showing pedunculated (A) well differentiated squamous cell carcinoma with keratin pearls invading the stalk connective tissue (A-C), (A, 1×; B and C, 200×); D: P16 immunoreactivity positive in 60% of tumor cells (200×).

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Anticancer Research
Vol. 38, Issue 7
July 2018
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Unusual Papillary Squamous Cell Carcinoma of the Tip of Tongue Presenting in a Patient Status Post Heart Transplant
FARAJ ALOTAIBY, FENGLIN SONG, BRIAN J. BOYCE, DENGFENG CAO, YULIN ZHAO, JINPING LAI
Anticancer Research Jul 2018, 38 (7) 4203-4206; DOI: 10.21873/anticanres.12715

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Unusual Papillary Squamous Cell Carcinoma of the Tip of Tongue Presenting in a Patient Status Post Heart Transplant
FARAJ ALOTAIBY, FENGLIN SONG, BRIAN J. BOYCE, DENGFENG CAO, YULIN ZHAO, JINPING LAI
Anticancer Research Jul 2018, 38 (7) 4203-4206; DOI: 10.21873/anticanres.12715
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Keywords

  • Tip of tongue
  • papillary squamous cell carcinoma
  • heart transplant
  • p16 immunohistochemistry
  • HPV in situ hybridization
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