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Research ArticleClinical Studies

Pathological High-risk Renal Cell Carcinoma: Trends in Clinical Characteristics Over 25 Years

ETTORE DI TRAPANI, PAOLO DELL'OGLIO, ALESSANDRO LARCHER, ALESSANDRO NINI, FABIO MUTTIN, FRANCESCO CIANFLONE, FEDERICO DEHÒ, RAYAN MATLOOB, DARIO DI TRAPANI, MASSIMO FRESCHI, ANDREA SALONIA, ALBERTO BRIGANTI, FRANCESCO MONTORSI, ROBERTO BERTINI and UMBERTO CAPITANIO
Anticancer Research July 2018, 38 (7) 4123-4130; DOI: https://doi.org/10.21873/anticanres.12703
ETTORE DI TRAPANI
1Department of Urology and Division of Experimental Oncology, URI, Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy
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PAOLO DELL'OGLIO
1Department of Urology and Division of Experimental Oncology, URI, Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy
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ALESSANDRO LARCHER
1Department of Urology and Division of Experimental Oncology, URI, Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy
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ALESSANDRO NINI
1Department of Urology and Division of Experimental Oncology, URI, Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy
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FABIO MUTTIN
1Department of Urology and Division of Experimental Oncology, URI, Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy
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FRANCESCO CIANFLONE
1Department of Urology and Division of Experimental Oncology, URI, Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy
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FEDERICO DEHÒ
1Department of Urology and Division of Experimental Oncology, URI, Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy
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RAYAN MATLOOB
1Department of Urology and Division of Experimental Oncology, URI, Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy
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DARIO DI TRAPANI
2Department of Urology, Ospedale Niguarda Ca' Granda, Milan, Italy
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MASSIMO FRESCHI
3Department of Pathology, URI, Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy
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ANDREA SALONIA
1Department of Urology and Division of Experimental Oncology, URI, Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy
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ALBERTO BRIGANTI
1Department of Urology and Division of Experimental Oncology, URI, Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy
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FRANCESCO MONTORSI
1Department of Urology and Division of Experimental Oncology, URI, Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy
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ROBERTO BERTINI
1Department of Urology and Division of Experimental Oncology, URI, Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy
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UMBERTO CAPITANIO
1Department of Urology and Division of Experimental Oncology, URI, Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy
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  • For correspondence: umbertocapitanio{at}gmail.com
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    Figure 1.

    Temporal trends of median age at diagnosis (A), median body mass index (B), gender (C), comorbidity (D) and clinical presentation (E), as recorded in 741 pathologically high-risk renal cell carcinoma patients treated with partial or radical nephrectomy between 1987 and 2011 at a single tertiary referral center (dotted lines: 95% confidence interval).

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    Figure 2.

    Temporal trends of median clinical tumor size (A), clinical stage (B), clinical nodal status (C), clinical metastases (D), as recorded in 741 pathologically high-risk renal cell carcinoma patients treated with partial or radical nephrectomy between 1987 and 2011 at a single tertiary referral center (dotted lines: 95% confidence interval).

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    Figure 3.

    Temporal trends of treatment among high-risk renal cell carcinoma patients: radical nephrectomy vs. partial nephrectomy, as recorded between 1987 and 2011 in 741 patients from a single tertiary referral center (dotted lines: 95% confidence interval).

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July 2018
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Pathological High-risk Renal Cell Carcinoma: Trends in Clinical Characteristics Over 25 Years
ETTORE DI TRAPANI, PAOLO DELL'OGLIO, ALESSANDRO LARCHER, ALESSANDRO NINI, FABIO MUTTIN, FRANCESCO CIANFLONE, FEDERICO DEHÒ, RAYAN MATLOOB, DARIO DI TRAPANI, MASSIMO FRESCHI, ANDREA SALONIA, ALBERTO BRIGANTI, FRANCESCO MONTORSI, ROBERTO BERTINI, UMBERTO CAPITANIO
Anticancer Research Jul 2018, 38 (7) 4123-4130; DOI: 10.21873/anticanres.12703

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Pathological High-risk Renal Cell Carcinoma: Trends in Clinical Characteristics Over 25 Years
ETTORE DI TRAPANI, PAOLO DELL'OGLIO, ALESSANDRO LARCHER, ALESSANDRO NINI, FABIO MUTTIN, FRANCESCO CIANFLONE, FEDERICO DEHÒ, RAYAN MATLOOB, DARIO DI TRAPANI, MASSIMO FRESCHI, ANDREA SALONIA, ALBERTO BRIGANTI, FRANCESCO MONTORSI, ROBERTO BERTINI, UMBERTO CAPITANIO
Anticancer Research Jul 2018, 38 (7) 4123-4130; DOI: 10.21873/anticanres.12703
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