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Review ArticleProceedings of the Joint International Symposium “Vitamin D in Prevention and Therapy” and “Biologic Effects of Light”, June 21-23, 2017 (Homburg/Saar, Germany)R

Vitamin D: Current Guidelines and Future Outlook

STEFAN PILZ, CHRISTIAN TRUMMER, MARLENE PANDIS, VERENA SCHWETZ, FELIX ABERER, MARTIN GRÜBLER, NICOLAS VERHEYEN, ANDREAS TOMASCHITZ and WINFRIED MÄRZ
Anticancer Research February 2018, 38 (2) 1145-1151;
STEFAN PILZ
1Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria
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  • For correspondence: stefan.pilz@chello.at
CHRISTIAN TRUMMER
1Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria
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MARLENE PANDIS
1Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria
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VERENA SCHWETZ
1Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria
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FELIX ABERER
1Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria
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MARTIN GRÜBLER
1Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria
2Swiss Cardiovascular Center Bern, Department of Cardiology, Bern University Hospital, Bern, Switzerland
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NICOLAS VERHEYEN
3Department of Cardiology, Medical University of Graz, Graz, Austria
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ANDREAS TOMASCHITZ
4Specialist Clinic of Rehabilitation Bad Gleichenberg, Bad Gleichenberg, Austria
5Medical Clinic V (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany
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WINFRIED MÄRZ
5Medical Clinic V (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany
6Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria
7Synlab Academy, Synlab Laboratory Services GmbH, Mannheim, Germany
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Abstract

Vitamin D is of public health interest because its deficiency is common and is associated with musculoskeletal diseases, as well as extraskeletal diseases, such as cancer, cardiovascular diseases, and infections. Several health authorities have reviewed the existing literature and published nutritional vitamin D guidelines for the general population. There was a wide consensus that serum 25-hydroxyvitamin D [25(OH)D] concentration should be used to assess vitamin D status and intake, and that musculoskeletal, and not extraskeletal, effects of vitamin D should be the basis for nutritional vitamin D guidelines. Recommended target levels for 25(OH)D range from 25 to 50 nmol/l (10 to 20 ng/ml), corresponding to a vitamin D intake of 400 to 800 International Units (10 to 20 μg) per day. It is of concern that significant sections of the general population do not meet these recommended vitamin D levels. This definitely requires action from a public health perspective.

  • Vitamin D
  • guidelines
  • supplementation
  • epidemiology
  • 25(OH)D
  • review
  • Received October 30, 2017.
  • Revision received December 5, 2017.
  • Accepted December 6, 2017.
  • Copyright© 2018, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved
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Anticancer Research: 38 (2)
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February 2018
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Vitamin D: Current Guidelines and Future Outlook
STEFAN PILZ, CHRISTIAN TRUMMER, MARLENE PANDIS, VERENA SCHWETZ, FELIX ABERER, MARTIN GRÜBLER, NICOLAS VERHEYEN, ANDREAS TOMASCHITZ, WINFRIED MÄRZ
Anticancer Research Feb 2018, 38 (2) 1145-1151;

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Vitamin D: Current Guidelines and Future Outlook
STEFAN PILZ, CHRISTIAN TRUMMER, MARLENE PANDIS, VERENA SCHWETZ, FELIX ABERER, MARTIN GRÜBLER, NICOLAS VERHEYEN, ANDREAS TOMASCHITZ, WINFRIED MÄRZ
Anticancer Research Feb 2018, 38 (2) 1145-1151;
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Keywords

  • vitamin D
  • guidelines
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  • epidemiology
  • 25(OH)D
  • review
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