Article Figures & Data
Figures
- Figure 1.
Effect of MU and 5-FU on the proliferation of MIA PaCa-2 cells. Cells were incubated with MU and/or 5-FU. Cell number was examined as described in Materials and Methods.
- Figure 2.
Effect of MU on the intracellular migration of 5-FU. Concentration of intracellular 5-FU. Concentration was examined as described in Materials and Methods. Each point represents the average of quadrant independent assays.
- Figure 3.
Antitumor effect of MU and 5-FU. A: Change over time of tumor volume. Tumor size was measured with calipers and its volume was calculated as described in the Materials and Methods section. The data represents the means for 11-14 mice. *p<0.05 (Student's t-test, control versus 5-FU plus MU group). B: Survival time of mice. Survival time was compared by log-rank analysis of Kaplan–Meier curves. *p<0.05 (control versus 5-FU plus MU group).
- Figure 4.
Electron microscopy of tumors. The stroma of pancreatic cancer tumors. Tumors were observed by electron microscope, A and C: after 5-FU treatment; B and D: after MU and 5-FU treatment. Bar indicates 2.5 μm (A and B) and 1.0 μm (C and D). The arrow shows a stroma.
