Figure 2. Relative mRNA expression of a) CAT (catalase), b) SOD2 (superoxide dismutase 2), c) GSTP1 (glutathione S-transferase P1), and d) GPX1 (glutathione peroxidase 1) in LT97 colon adenoma cells after incubation with fermentation supernatants (FS, 2.5 and 5%) of raw and roasted hazelnuts (RC1=140.6°C/25 min, RC2=155.1°C/20 min and RC3=180.4°C/21 min) and controls (4 mM butyrate, blank, Synergy1®) for 24 h (mean+SD, n=3). Values represent fold changes on the basis of a medium control (set as 1, dashed line). Significant differences compared to the medium control (*p≤0.05, **p≤0.01, ***p≤0.001), to the blank control (##p≤0.01, ###p≤0.001) and between FS (a-fp≤0.05, equal letters represent significant differences) were obtained by two-way Anova/Bonferroni post-test. Significant differences between 2.5 and 5% were obtained by unpaired Student's t-test (†p≤0.05, ††p≤0.01, †††p≤0.001).