Clinical Outcomes of Resectable Esophageal Cancer with Supraclavicular Lymph Node Metastases Treated with Curative Intent

YOSHITAKA HONMA; NOBUKAZU HOKAMURA; KENGO NAGASHIMA; KAZUKI SUDO; HIROKAZU SHOJI; SATORU IWASA; ATSUO TAKASHIMA; KEN KATO; TETSUYA HAMAGUCHI; NARIKAZU BOKU; REI UMEZAWA; YOSHINORI ITO; JUN ITAMI; KAZUO KOYANAGI; HIROYASU IGAKI; YUJI TACHIMORI

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Clinical Outcomes of Resectable Esophageal Cancer with Supraclavicular Lymph Node Metastases Treated with Curative Intent

YOSHITAKA HONMA, NOBUKAZU HOKAMURA, KENGO NAGASHIMA, KAZUKI SUDO, HIROKAZU SHOJI, SATORU IWASA, ATSUO TAKASHIMA, KEN KATO, TETSUYA HAMAGUCHI, NARIKAZU BOKU, REI UMEZAWA, YOSHINORI ITO, JUN ITAMI, KAZUO KOYANAGI, HIROYASU IGAKI and YUJI TACHIMORI

Anticancer Research July 2017, 37 (7) 3741-3749;

YOSHITAKA HONMA

1Gastrointestinal Medical Oncology Division, National Cancer Center Hospital, Tokyo, Japan

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For correspondence: yohonma{at}ncc.go.jp

NOBUKAZU HOKAMURA

2Esophageal Surgery Division, National Cancer Center Hospital, Tokyo, Japan

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KENGO NAGASHIMA

3Department of Global Clinical Research, Graduate School of Medicine, Chiba University, Chiba, Japan

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KAZUKI SUDO

1Gastrointestinal Medical Oncology Division, National Cancer Center Hospital, Tokyo, Japan

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HIROKAZU SHOJI

1Gastrointestinal Medical Oncology Division, National Cancer Center Hospital, Tokyo, Japan

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SATORU IWASA

1Gastrointestinal Medical Oncology Division, National Cancer Center Hospital, Tokyo, Japan

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ATSUO TAKASHIMA

1Gastrointestinal Medical Oncology Division, National Cancer Center Hospital, Tokyo, Japan

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KEN KATO

1Gastrointestinal Medical Oncology Division, National Cancer Center Hospital, Tokyo, Japan

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TETSUYA HAMAGUCHI

1Gastrointestinal Medical Oncology Division, National Cancer Center Hospital, Tokyo, Japan

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NARIKAZU BOKU

1Gastrointestinal Medical Oncology Division, National Cancer Center Hospital, Tokyo, Japan

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REI UMEZAWA

4Department of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan

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YOSHINORI ITO

4Department of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan

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JUN ITAMI

4Department of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan

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KAZUO KOYANAGI

2Esophageal Surgery Division, National Cancer Center Hospital, Tokyo, Japan

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HIROYASU IGAKI

2Esophageal Surgery Division, National Cancer Center Hospital, Tokyo, Japan

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YUJI TACHIMORI

2Esophageal Surgery Division, National Cancer Center Hospital, Tokyo, Japan

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Figure 1.
Regimens for perioperative treatment. 5-FU: 5-Fluorouracil.
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Figure 2.
Regimens for definitive chemoradiotherapy. 5-FU: 5-Fluorouracil.
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Figure 3.
Progression-free survival of patients according to therapy. dCRT: definitive chemoradiotherapy; S alone: surgery alone; S/Tx: surgery plus perioperative therapy.
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Figure 4.
Overall survival of patients according to therapy. dCRT: definitive chemoradiotherapy; S alone: surgery alone; S/Tx: surgery plus perioperative therapy.

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Keywords

esophageal cancer
supraclavicular lymph node metastases
surgery
chemoradiotherapy

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