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Research ArticleClinical Studies

Does Rectus Sheath Block Analgesia Alter Levels of the Oxidative Stress Biomarker Glutathione Peroxidase: A Randomised Trial of Patients with Cancer and Benign Disease

MARTIN PURDY, JARI KÄRKKÄINEN, MERJA KOKKI, MAARIT ANTTILA, SAMULI ASPINEN, PETRI JUVONEN, HANNU KOKKI, KARI PULKKI, TUOMO RANTANEN and MATTI ESKELINEN
Anticancer Research February 2017, 37 (2) 897-902;
MARTIN PURDY
1Department of Surgery, Kuopio University Hospital and School of Medicine, University of Eastern Finland, Kuopio, Finland
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JARI KÄRKKÄINEN
1Department of Surgery, Kuopio University Hospital and School of Medicine, University of Eastern Finland, Kuopio, Finland
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MERJA KOKKI
2Department of Anaesthesia and Operative Services, Kuopio University Hospital and School of Medicine, University of Eastern Finland, Kuopio, Finland
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MAARIT ANTTILA
3Department of Gynaecology, Kuopio University Hospital, Kuopio, Finland
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SAMULI ASPINEN
1Department of Surgery, Kuopio University Hospital and School of Medicine, University of Eastern Finland, Kuopio, Finland
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PETRI JUVONEN
1Department of Surgery, Kuopio University Hospital and School of Medicine, University of Eastern Finland, Kuopio, Finland
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HANNU KOKKI
2Department of Anaesthesia and Operative Services, Kuopio University Hospital and School of Medicine, University of Eastern Finland, Kuopio, Finland
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KARI PULKKI
4Department of Clinical Chemistry, School of Medicine, University of Eastern Finland
5Eastern Finland Laboratory Centre, Kuopio, Finland
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TUOMO RANTANEN
1Department of Surgery, Kuopio University Hospital and School of Medicine, University of Eastern Finland, Kuopio, Finland
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MATTI ESKELINEN
1Department of Surgery, Kuopio University Hospital and School of Medicine, University of Eastern Finland, Kuopio, Finland
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  • For correspondence: matti.eskelinen{at}kuh.fi
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    CONSORT figure of the study design.

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    Figure 2.

    The jitterplot of the individual glutathione peroxidase (GPX1) values immediately after surgery (POP1) according to the diagnosis of the patients as benign disease (n=15) or cancer (n=29).

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February 2017
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Does Rectus Sheath Block Analgesia Alter Levels of the Oxidative Stress Biomarker Glutathione Peroxidase: A Randomised Trial of Patients with Cancer and Benign Disease
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Does Rectus Sheath Block Analgesia Alter Levels of the Oxidative Stress Biomarker Glutathione Peroxidase: A Randomised Trial of Patients with Cancer and Benign Disease
MARTIN PURDY, JARI KÄRKKÄINEN, MERJA KOKKI, MAARIT ANTTILA, SAMULI ASPINEN, PETRI JUVONEN, HANNU KOKKI, KARI PULKKI, TUOMO RANTANEN, MATTI ESKELINEN
Anticancer Research Feb 2017, 37 (2) 897-902;

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Does Rectus Sheath Block Analgesia Alter Levels of the Oxidative Stress Biomarker Glutathione Peroxidase: A Randomised Trial of Patients with Cancer and Benign Disease
MARTIN PURDY, JARI KÄRKKÄINEN, MERJA KOKKI, MAARIT ANTTILA, SAMULI ASPINEN, PETRI JUVONEN, HANNU KOKKI, KARI PULKKI, TUOMO RANTANEN, MATTI ESKELINEN
Anticancer Research Feb 2017, 37 (2) 897-902;
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  • Psychological Stress Versus Outcome in Patients With Breast Disease and Breast Cancer: A Prospective 25-year Follow-up Study in Patients With Breast Cancer Symptoms
  • Plasma Concentration of the Lipid Peroxidation (LP) Biomarker 4-Hydroxynonenal (4-HNE) in Benign and Cancer Patients
  • The Induction of Antioxidant Catalase Enzyme With Decrease of Plasma Malonidialdehyde: An Important Reactive Oxidative Species Inhibiting Mechanism
  • The Rectus Sheath Block (RSB) Analgesia Following Laparotomy Could Affect Malonidialdehyde (MDA) Concentrations in Benign Disease and Cancer
  • Brief Pain Inventory (BPI) Health Survey After Midline Laparotomy With the Rectus Sheath Block (RSB) Analgesia: A Randomised Trial of Patients With Cancer and Benign Disease
  • Rectus Sheath Block (RSB) Analgesia Could Enhance Significantly the Patient Satisfaction Following Midline Laparotomy in Benign Disease and in Cancer: A Prospective Study With Special Reference to Nitrosative Stress Marker Nitrotyrosine (NT) Plasma Concentrations
  • Nitrotyrosine (NT), a Nitrosative Stress Biomarker, Plasma Concentrations in Gallstone Disease and Cancer Patients
  • Plasma Catalase in Relation to Pain Following Midline Laparotomy: A Prospective Study of Patients with Benign Diseases and Patients with Cancer
  • Gallstone Patients with Enhanced Oxidative Stress Biomarker Superoxide Dismutase (SOD1) Plasma Levels Have Significantly Lower Number of Postoperative Analgesic Oxycodone Doses: A Prospective Study with Special Reference to Cancer Patients
  • Patients with Increased Levels of the Oxidative Stress Biomarker SOD1 Appear to Have Diminished Postoperative Pain After Midline Laparotomy: A Randomised Trial with Special Reference to Postoperative Pain Score (NRS)
  • Plasma Glutathione Peroxidase (GPX1) Levels and Oxidative Stress in Gallstone Patients Operated with Two Different Cholecystectomy Techniques: A Randomized Study with Special Reference to Cancer Patients
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Keywords

  • cancer
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  • analgesia
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