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Research ArticleClinical Studies

Efficacy and Toxicity of Panitumumab After Progression on Cetuximab and Predictive Value of MiR-31-5p in Metastatic Wild-type KRAS Colorectal Cancer Patients

IGOR KISS, JITKA MLCOCHOVA, ZBYNEK BORTLICEK, ALEXANDR POPRACH, JIRI DRABEK, PETRA VYCHYTILOVA-FALTEJSKOVA, MAREK SVOBODA, TOMAS BUCHLER, STANISLAV BATKO, ALES RYSKA, MARIAN HAJDUCH and ONDREJ SLABY
Anticancer Research September 2016, 36 (9) 4955-4959;
IGOR KISS
1Department of Comprehensive Cancer Care, Masaryk Memorial Cancer Institute, Brno, Czech Republic
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  • For correspondence: kiss{at}mou.cz on.slaby{at}gmail.com
JITKA MLCOCHOVA
2Central European Institute of Technology, Masaryk University, Brno, Czech Republic
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ZBYNEK BORTLICEK
3Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, Czech Republic
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ALEXANDR POPRACH
1Department of Comprehensive Cancer Care, Masaryk Memorial Cancer Institute, Brno, Czech Republic
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JIRI DRABEK
4Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic
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PETRA VYCHYTILOVA-FALTEJSKOVA
1Department of Comprehensive Cancer Care, Masaryk Memorial Cancer Institute, Brno, Czech Republic
2Central European Institute of Technology, Masaryk University, Brno, Czech Republic
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MAREK SVOBODA
1Department of Comprehensive Cancer Care, Masaryk Memorial Cancer Institute, Brno, Czech Republic
2Central European Institute of Technology, Masaryk University, Brno, Czech Republic
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TOMAS BUCHLER
5Department of Oncology, Thomayer Hospital and Charles University First Faculty of Medicine, Prague, Czech Republic
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STANISLAV BATKO
6Department of Oncology, Motol University Hospital and Charles University Second Faculty of Medicine, Prague, Czech Republic
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ALES RYSKA
7The Fingerland Department of Pathology, Charles University Medical Faculty Hospital, Hradec Kralove, Czech Republic
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MARIAN HAJDUCH
4Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic
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ONDREJ SLABY
1Department of Comprehensive Cancer Care, Masaryk Memorial Cancer Institute, Brno, Czech Republic
2Central European Institute of Technology, Masaryk University, Brno, Czech Republic
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  • For correspondence: kiss{at}mou.cz on.slaby{at}gmail.com
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Article Information

vol. 36 no. 9 4955-4959
PMID 
27630355

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received July 12, 2016
  • Revision received July 19, 2016
  • Accepted July 20, 2016
  • Published online September 14, 2016.

Copyright & Usage 
Copyright© 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved

Author Information

  1. IGOR KISS1⇑,
  2. JITKA MLCOCHOVA2,
  3. ZBYNEK BORTLICEK3,
  4. ALEXANDR POPRACH1,
  5. JIRI DRABEK4,
  6. PETRA VYCHYTILOVA-FALTEJSKOVA1,2,
  7. MAREK SVOBODA1,2,
  8. TOMAS BUCHLER5,
  9. STANISLAV BATKO6,
  10. ALES RYSKA7,
  11. MARIAN HAJDUCH4 and
  12. ONDREJ SLABY1,2⇑
  1. 1Department of Comprehensive Cancer Care, Masaryk Memorial Cancer Institute, Brno, Czech Republic
  2. 2Central European Institute of Technology, Masaryk University, Brno, Czech Republic
  3. 3Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, Czech Republic
  4. 4Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic
  5. 5Department of Oncology, Thomayer Hospital and Charles University First Faculty of Medicine, Prague, Czech Republic
  6. 6Department of Oncology, Motol University Hospital and Charles University Second Faculty of Medicine, Prague, Czech Republic
  7. 7The Fingerland Department of Pathology, Charles University Medical Faculty Hospital, Hradec Kralove, Czech Republic
  1. Correspondence to: Igor Kiss, MD, Ph.D., Department of Comprehensive Cancer Care, Masaryk Memorial Cancer Institute, Zluty kopec 7, 656 53 Brno, Czech Republic. Tel: +420 543131111, e-mail: kiss{at}mou.cz and Assoc. Prof. Ondrej Slaby, PhD, Central European Institute of Technology (CEITEC), Masaryk University, University Campus Bohunice, Building A35, Room 217, Kamenice 5, 625 00 Brno, Czech Republic. Tel: +420 776494155, e-mail: on.slaby{at}gmail.com
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Efficacy and Toxicity of Panitumumab After Progression on Cetuximab and Predictive Value of MiR-31-5p in Metastatic Wild-type KRAS Colorectal Cancer Patients
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Efficacy and Toxicity of Panitumumab After Progression on Cetuximab and Predictive Value of MiR-31-5p in Metastatic Wild-type KRAS Colorectal Cancer Patients
IGOR KISS, JITKA MLCOCHOVA, ZBYNEK BORTLICEK, ALEXANDR POPRACH, JIRI DRABEK, PETRA VYCHYTILOVA-FALTEJSKOVA, MAREK SVOBODA, TOMAS BUCHLER, STANISLAV BATKO, ALES RYSKA, MARIAN HAJDUCH, ONDREJ SLABY
Anticancer Research Sep 2016, 36 (9) 4955-4959;

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Efficacy and Toxicity of Panitumumab After Progression on Cetuximab and Predictive Value of MiR-31-5p in Metastatic Wild-type KRAS Colorectal Cancer Patients
IGOR KISS, JITKA MLCOCHOVA, ZBYNEK BORTLICEK, ALEXANDR POPRACH, JIRI DRABEK, PETRA VYCHYTILOVA-FALTEJSKOVA, MAREK SVOBODA, TOMAS BUCHLER, STANISLAV BATKO, ALES RYSKA, MARIAN HAJDUCH, ONDREJ SLABY
Anticancer Research Sep 2016, 36 (9) 4955-4959;
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Keywords

  • metastatic colorectal cancer
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