Change in Serum Lactate Dehydrogenase Is Associated with Outcome of Patients with Advanced-stage NSCLC Treated with Erlotinib

ONDREJ FIALA; MILOS PESEK; JINDRICH FINEK; ONDREJ TOPOLCAN; JAROSLAV RACEK; MARTIN SVATON; RADEK KUCERA; MAREK MINARIK; LUCIE BENESOVA; ZBYNEK BORTLICEK; RENATA CHLOUPKOVA; ALEXANDR POPRACH; TOMAS BUCHLER

Research ArticleClinical Studies

Change in Serum Lactate Dehydrogenase Is Associated with Outcome of Patients with Advanced-stage NSCLC Treated with Erlotinib

ONDREJ FIALA, MILOS PESEK, JINDRICH FINEK, ONDREJ TOPOLCAN, JAROSLAV RACEK, MARTIN SVATON, RADEK KUCERA, MAREK MINARIK, LUCIE BENESOVA, ZBYNEK BORTLICEK, RENATA CHLOUPKOVA, ALEXANDR POPRACH and TOMAS BUCHLER

Anticancer Research May 2016, 36 (5) 2459-2465;

ONDREJ FIALA

1Department of Oncology and Radiotherapy, Medical School and Teaching Hospital in Pilsen, Charles University in Prague, Prague, Czech Republic

2Biomedical Center, Faculty of Medicine in Pilsen, Charles University in Prague, Prague, Czech Republic

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For correspondence: fiala.o@centrum.cz

MILOS PESEK

3Department of Pneumology, Medical School and Teaching Hospital in Pilsen, Charles University in Prague, Prague, Czech Republic

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JINDRICH FINEK

1Department of Oncology and Radiotherapy, Medical School and Teaching Hospital in Pilsen, Charles University in Prague, Prague, Czech Republic

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ONDREJ TOPOLCAN

4Department of Nuclear Medicine, Medical School and Teaching Hospital in Pilsen, Charles University in Prague, Prague, Czech Republic

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JAROSLAV RACEK

5Istitute of Clinical Biochemistry and Hematology, Medical School and Teaching Hospital in Pilsen, Charles University in Prague, Prague, Czech Republic

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MARTIN SVATON

3Department of Pneumology, Medical School and Teaching Hospital in Pilsen, Charles University in Prague, Prague, Czech Republic

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RADEK KUCERA

4Department of Nuclear Medicine, Medical School and Teaching Hospital in Pilsen, Charles University in Prague, Prague, Czech Republic

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MAREK MINARIK

6Center for Applied Genomics of Solid Tumours, Genomac Research Institute, Prague, Czech Republic

7Department of Analytical Chemistry, Faculty of Sciences, Charles University in Prague, Prague, Czech Republic

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LUCIE BENESOVA

6Center for Applied Genomics of Solid Tumours, Genomac Research Institute, Prague, Czech Republic

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ZBYNEK BORTLICEK

8Institute of Biostatistics and Analysis, Faculty of Medicine, Masaryk University, Brno, Czech Republic

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RENATA CHLOUPKOVA

8Institute of Biostatistics and Analysis, Faculty of Medicine, Masaryk University, Brno, Czech Republic

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ALEXANDR POPRACH

9Department of Comprehensive Cancer Care, Masaryk Memorial Cancer Institute and Faculty of Medicine, Masaryk University, Brno, Czech Republic

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TOMAS BUCHLER

10Department of Oncology and First Faculty of Medicine, Charles University and Thomayer Hospital, Prague, Czech Republic

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Figure 1.
Kaplan-Meier plots showing progression-free (A) and overall (B) survival according to change in LDH serum level.

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Anticancer Research

Vol. 36, Issue 5

May 2016

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