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Research ArticleClinical Studies

Elimination of Cigarette Smoke-derived Acetaldehyde in Saliva by Slow-release L-Cysteine Lozenge Is a Potential New Method to Assist Smoking Cessation. A Randomised, Double-blind, Placebo-controlled Intervention

KARI SYRJÄNEN, JOHANNA SALMINEN, ULLA ARESVUO, PANU HENDOLIN, LEA PALOHEIMO, CARITA EKLUND, MIKKO SALASPURO and OSMO SUOVANIEMI
Anticancer Research May 2016, 36 (5) 2297-2306;
KARI SYRJÄNEN
1Department of Clinical Research, Biohit Oyj, Helsinki, Finland
2Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, SP, Brazil
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  • For correspondence: kari.syrjanen@biohit.fi
JOHANNA SALMINEN
1Department of Clinical Research, Biohit Oyj, Helsinki, Finland
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ULLA ARESVUO
1Department of Clinical Research, Biohit Oyj, Helsinki, Finland
3Helsinki Metropolitan University of Applied Sciences, Helsinki, Finland
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PANU HENDOLIN
4Department of Research and Development, Biohit Oyj, Helsinki, Finland
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LEA PALOHEIMO
4Department of Research and Development, Biohit Oyj, Helsinki, Finland
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CARITA EKLUND
4Department of Research and Development, Biohit Oyj, Helsinki, Finland
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MIKKO SALASPURO
5Research Unit on Acetaldehyde and Cancer, University of Helsinki, Helsinki, Finland
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OSMO SUOVANIEMI
1Department of Clinical Research, Biohit Oyj, Helsinki, Finland
4Department of Research and Development, Biohit Oyj, Helsinki, Finland
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Article Information

vol. 36 no. 5 2297-2306
PubMed 
27127136

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received February 26, 2016
  • Revision received April 7, 2016
  • Accepted April 11, 2016
  • Published online April 28, 2016.

Copyright & Usage 
Copyright© 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved

Author Information

  1. KARI SYRJÄNEN1,2⇑,
  2. JOHANNA SALMINEN1,
  3. ULLA ARESVUO1,3,
  4. PANU HENDOLIN4,
  5. LEA PALOHEIMO4,
  6. CARITA EKLUND4,
  7. MIKKO SALASPURO5 and
  8. OSMO SUOVANIEMI1,4
  1. 1Department of Clinical Research, Biohit Oyj, Helsinki, Finland
  2. 2Molecular Oncology Research Center, Barretos Cancer Hospital, Barretos, SP, Brazil
  3. 3Helsinki Metropolitan University of Applied Sciences, Helsinki, Finland
  4. 4Department of Research and Development, Biohit Oyj, Helsinki, Finland
  5. 5Research Unit on Acetaldehyde and Cancer, University of Helsinki, Helsinki, Finland
  1. Correspondence to: Professor Kari Syrjänen, MD, Ph.D., FIAC, Head, Department of Clinical Research, Biohit Oyj, Laippatie 1, FIN-00880 Helsinki, Finland. Tel: +358 405566810, Fax: +358 97732867, e-mail: kari.syrjanen{at}biohit.fi
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Anticancer Research: 36 (5)
Anticancer Research
Vol. 36, Issue 5
May 2016
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Elimination of Cigarette Smoke-derived Acetaldehyde in Saliva by Slow-release L-Cysteine Lozenge Is a Potential New Method to Assist Smoking Cessation. A Randomised, Double-blind, Placebo-controlled Intervention
KARI SYRJÄNEN, JOHANNA SALMINEN, ULLA ARESVUO, PANU HENDOLIN, LEA PALOHEIMO, CARITA EKLUND, MIKKO SALASPURO, OSMO SUOVANIEMI
Anticancer Research May 2016, 36 (5) 2297-2306;

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Elimination of Cigarette Smoke-derived Acetaldehyde in Saliva by Slow-release L-Cysteine Lozenge Is a Potential New Method to Assist Smoking Cessation. A Randomised, Double-blind, Placebo-controlled Intervention
KARI SYRJÄNEN, JOHANNA SALMINEN, ULLA ARESVUO, PANU HENDOLIN, LEA PALOHEIMO, CARITA EKLUND, MIKKO SALASPURO, OSMO SUOVANIEMI
Anticancer Research May 2016, 36 (5) 2297-2306;
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Keywords

  • Smoking intervention
  • clinical trial
  • randomized
  • double-blind
  • placebo-controlled
  • L-cysteine
  • slow-release
  • lozenge
  • smoking quit
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