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Research ArticlePROCEEDINGS OF THE INTERNATIONAL SYMPOSIUM “BIOLOGIC EFFECTS OF LIGHT” (Homburg/Saar, Germany)

Layer Thickness of SPF 30 Sunscreen and Formation of Pre-vitamin D

MANTAS GRIGALAVICIUS, VLADIMIR IANI and ASTA JUZENIENE
Anticancer Research March 2016, 36 (3) 1409-1415;
MANTAS GRIGALAVICIUS
Department of Radiation Biology, Oslo University Hospital, The Norwegian Radium Hospital, Montebello, Oslo, Norway
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VLADIMIR IANI
Department of Radiation Biology, Oslo University Hospital, The Norwegian Radium Hospital, Montebello, Oslo, Norway
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ASTA JUZENIENE
Department of Radiation Biology, Oslo University Hospital, The Norwegian Radium Hospital, Montebello, Oslo, Norway
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  • For correspondence: astaj@rr-research.no
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Abstract

Background: Most studies have demonstrated that sunscreens with lower sun protection factor (SPF) do not prevent the production of vitamin D because much lower amount of sunscreen (SPF<30) is applied than recommended (2 mg/cm2) indicating that a significant amount of UV radiation can penetrate the skin. Since less sunscreen is applied, higher SPF sunscreens may be used to achieve the desired protection. However, there is little information regarding the application of high-SPF sunscreen and vitamin D formation. The aim of this study was to measure the influence of the amount of two SPF 30 sunscreens on pre-vitamin D formation in a cuvette with 7-dehydrocholesterol. Results: Sunscreen with physical (reflecting) or chemical (absorbing) UV filters exhibits different levels of protection in vitro even if the SPF is the same. The level of photoprotection is differentially reduced when less sunscreen than the recommended application thickness is applied. Conclusion: The usual application of 0.8-1 mg/cm2 is below the recommended value of 2 mg/cm2, and pre-vitamin D may be formed when lower amounts of SPF ≤30 sunscreen are applied, showing that a significant amount of UV radiation may enter the skin.

  • Sunscreen
  • skin protection
  • solar ultraviolet radiation
  • 7-dehydrocholesterol
  • vitamin D
  • Received November 30, 2015.
  • Revision received January 13, 2016.
  • Accepted January 14, 2016.
  • Copyright© 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved
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Anticancer Research: 36 (3)
Anticancer Research
Vol. 36, Issue 3
March 2016
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Layer Thickness of SPF 30 Sunscreen and Formation of Pre-vitamin D
MANTAS GRIGALAVICIUS, VLADIMIR IANI, ASTA JUZENIENE
Anticancer Research Mar 2016, 36 (3) 1409-1415;

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Layer Thickness of SPF 30 Sunscreen and Formation of Pre-vitamin D
MANTAS GRIGALAVICIUS, VLADIMIR IANI, ASTA JUZENIENE
Anticancer Research Mar 2016, 36 (3) 1409-1415;
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Show more PROCEEDINGS OF THE INTERNATIONAL SYMPOSIUM “BIOLOGIC EFFECTS OF LIGHT” (Homburg/Saar, Germany)

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Keywords

  • Sunscreen
  • skin protection
  • solar ultraviolet radiation
  • 7-dehydrocholesterol
  • vitamin D
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