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Research ArticleClinical Studies

Clinicopathological Features of Surgically-resected Biliary Tract Cancer Following Chemo-radiation Therapy

SHOGO KOBAYASHI, KUNIHITO GOTOH, HIDENORI TAKAHASHI, HIROFUMI AKITA, SHIGERU MARUBASHI, TERUMASA YAMADA, TERUKI TESHIMA, KINJI NISHIYAMA, MASAHIKO YANO, HIROAKI OHIGASHI, OSAMU ISHIKAWA and MASATO SAKON
Anticancer Research January 2016, 36 (1) 335-342;
SHOGO KOBAYASHI
1Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka City, Osaka, Japan
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  • For correspondence: s-kobayashi@umin.ac.jp kobayasi-si@mc.pref.osaka.jp
KUNIHITO GOTOH
1Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka City, Osaka, Japan
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HIDENORI TAKAHASHI
1Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka City, Osaka, Japan
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HIROFUMI AKITA
1Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka City, Osaka, Japan
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SHIGERU MARUBASHI
1Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka City, Osaka, Japan
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TERUMASA YAMADA
1Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka City, Osaka, Japan
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TERUKI TESHIMA
2Department of Radiation Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka City, Osaka, Japan
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KINJI NISHIYAMA
2Department of Radiation Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka City, Osaka, Japan
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MASAHIKO YANO
1Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka City, Osaka, Japan
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HIROAKI OHIGASHI
1Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka City, Osaka, Japan
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OSAMU ISHIKAWA
1Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka City, Osaka, Japan
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MASATO SAKON
1Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka City, Osaka, Japan
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    Figure 1.

    Typical dose distribution of radiation for right hepatectomy. (A) Dose distribution around the bile duct. (B) Dose distribution around the hepatic artery in the hepatico-duodenal ligament.

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    Figure 2.

    Surgical and pathological results after chemo-radiation followed by surgery depended on whether the BTC was defined as initially resectable or un-resectable. The upper panel shows the category and number of patients. The lower panel shows the rate of R0 resection, negative lymph node metastasis, and negative surgical cut end among the two categories, initially resectable and initially un-resectable.

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    Figure 3.

    Survival curves after chemo-radiation followed by surgery, calculated from the time of surgery and the time of first treatment, shown for initially resectable and un-resectable cases. The left-upper panel shows a graph of overall survival from the surgery for the two categories, initially resectable and un-resectable. The right upper panel shows a graph of overall survival from the first treatment. The lower panel lists the actual percentage of 1- or 3-year survival after the surgery or the first treatment.

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Anticancer Research: 36 (1)
Anticancer Research
Vol. 36, Issue 1
January 2016
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Clinicopathological Features of Surgically-resected Biliary Tract Cancer Following Chemo-radiation Therapy
SHOGO KOBAYASHI, KUNIHITO GOTOH, HIDENORI TAKAHASHI, HIROFUMI AKITA, SHIGERU MARUBASHI, TERUMASA YAMADA, TERUKI TESHIMA, KINJI NISHIYAMA, MASAHIKO YANO, HIROAKI OHIGASHI, OSAMU ISHIKAWA, MASATO SAKON
Anticancer Research Jan 2016, 36 (1) 335-342;

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Clinicopathological Features of Surgically-resected Biliary Tract Cancer Following Chemo-radiation Therapy
SHOGO KOBAYASHI, KUNIHITO GOTOH, HIDENORI TAKAHASHI, HIROFUMI AKITA, SHIGERU MARUBASHI, TERUMASA YAMADA, TERUKI TESHIMA, KINJI NISHIYAMA, MASAHIKO YANO, HIROAKI OHIGASHI, OSAMU ISHIKAWA, MASATO SAKON
Anticancer Research Jan 2016, 36 (1) 335-342;
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Keywords

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  • chemo-radiation
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  • neoadjuvant treatment
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