Article Figures & Data
Figures
- Figure 1.
Experimental design.
- Figure 2.
Effect of IP-PA1 on the development of AD-like dorsal skin lesions in DFE-treated NC/Nga mice. A) Representative feature changes in DFE-induced skin lesions on the back. The photos were taken 31 days after sensitization of each group of mice. B) Changes in survey scores on the back were evaluated on days 7, 14, 21, and 31. Data are presented as mean±SE (**p<0.01 and *p<0.05). a, control group; b, DFE group; c, DFE+IP-PA1-L group; d, DFE+IP-PA1-H group. N=8 for all groups.
- Figure 3.
Effect of IP-PA1 on histological features of DFE-induced AD-like model in NC/Nga mice. A) Back skin lesions were fixed with formaldehyde and determined after staining with hematoxylin and eosin (HE). a, control group; b, DFE group; c, DFE+IP-PA1-L group; d, DFE+IP-PA1-H group (Scale bars: 100 μm). B) Number of CITs were counted in an area of 300 μm × 300 μm (900 μm2) of each skin lesion (**p<0.01).
- Figure 4.
Effect of IP-PA1 on serum IgE, periostin and TARC levels of DFE-induced AD-like model in NC/Nga mice. A) Effect of IP-PA1 on DFE-induced increase in the serum IgE level in NC/Nga mice. The level of serum IgE was measured with ELISA on days 0, 7, 14, 21 and 31. Data are presented as mean±SE (**p<0.01 and *p<0.05). a, control group; b, DFE group; c, DFE+IP-PA1-L group; d, DFE+IP-PA1-H group. N=8 for all groups. B) Effect of IP-PA1 on DFE-induced increase serum periostin and TARC level in NC/Nga mice. The level of serum periostin and TARC were measured with ELISA on day 0 and 31. Data are presented as mean±SE (**p<0.01 and *p<0.05). N=8 for all groups.
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