Gene Therapy for HIV. From Inception to a Possible Cure

Gene Therapy for HIV. From Inception to a Possible Cure. Edited by G. Bauer, J. S. Anderson. 2014, pp. 72, Eur 53.49, ISBN: 978-1-4939-0433-4. Springer Science + Business Media, New York, NY, USA.

This book discusses the unique aspects of this therapy, including its limitations and proper safety precautions and outline a path for a possible functional cure for HIV using stem cell gene therapy based on a cure already achieved with a bone marrow stem cell transplantation performed in Germany using donor stem cells with a naturally arising CCR5 mutation. In addition, the Brief provides a thorough and methodical explanation of the basics of gene therapy, gene therapy vector development, in vitro and in vivo models for HIV gene therapy and clinical applications of HIV gene therapy, including Good Manufacturing Practices.