Structural Genomics and Drug Discovery. Methods and Protocols

Structural Genomics and Drug Discovery. Methods and Protocols. Edited by W.F. Anderson. 2014, pp. 344, Eur 117.69, ISBN: 978-1-4939-0353-5. Springer Science + Business Media, New York, NY, USA.

This volume focuses on high throughput structure determination methods and how they can be applied to lay the groundwork for structure aided drug discovery. The methods and protocols that are described can be applied in any laboratory interested in using detailed structural information to advance the initial stages of drug discovery. Chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, this book seeks to aid scientists in the further study into structural genomics approach as an efficient initial step toward drug discovery and the methods described will be useful to anyone interested in moving in this direction.