Gene Function Analysis. Second Edition

Gene Function Analysis. Second Edition. Edited by Michael F. Ochs. 2014, pp. 416, Eur 117,69, ISBN: 978-1-62703-720-4. Springer Science + Business Media, New York, NY, USA.

The determination of protein function has been a major goal of molecular biology since the founding of the discipline. However, we now know that it is critical to establish the background in which gene function is determined and to perform experiments in multiple applicable backgrounds. This volume presents various computational and experimental techniques for identifying not only the function of an individual gene, but also the partners that work with that gene. The theme of data integration runs strongly through the computational techniques, with many focusing on gathering data from different sources and different biomolecular types. Experimental techniques have evolved to determine function in specific tissues and at specific times during development. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, this book seeks to serve both professionals and novices with a growing understanding of the complexity of gene function.