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Research ArticleClinical Studies

Evidence that Mifepristone, a Progesterone Receptor Antagonist, Can Cross the Blood Brain Barrier and Provide Palliative Benefits for Glioblastoma Multiforme Grade IV

JEROME H. CHECK, CARRIE WILSON, RACHAEL COHEN and MOJIRAYO SARUMI
Anticancer Research May 2014, 34 (5) 2385-2388;
JEROME H. CHECK
1Department of Obstetrics out Gynecology, Division of Reproductive Endocrinology and Infertility, Cooper Medical School of Rowan University, Camden, NJ, U.S.A.
2Cooper Institute For Reproductive Hormonal Disorders, P.C., Marlton, NJ, U.S.A.
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  • For correspondence: laurie@ccivf.com
CARRIE WILSON
2Cooper Institute For Reproductive Hormonal Disorders, P.C., Marlton, NJ, U.S.A.
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RACHAEL COHEN
2Cooper Institute For Reproductive Hormonal Disorders, P.C., Marlton, NJ, U.S.A.
3Department of Obstetrics and Gynecology, Philadelphia College of Osteopathic Medicine, Philadelphia, PA, U.S.A.
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MOJIRAYO SARUMI
1Department of Obstetrics out Gynecology, Division of Reproductive Endocrinology and Infertility, Cooper Medical School of Rowan University, Camden, NJ, U.S.A.
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Article Information

vol. 34 no. 5 2385-2388
PubMed 
24778047

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received February 19, 2014
  • Revision received March 17, 2014
  • Accepted March 18, 2014
  • Published online April 28, 2014.

Copyright & Usage 
Copyright© 2014 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved

Author Information

  1. JEROME H. CHECK1,2⇑,
  2. CARRIE WILSON2,
  3. RACHAEL COHEN2,3 and
  4. MOJIRAYO SARUMI1
  1. 1Department of Obstetrics out Gynecology, Division of Reproductive Endocrinology and Infertility, Cooper Medical School of Rowan University, Camden, NJ, U.S.A.
  2. 2Cooper Institute For Reproductive Hormonal Disorders, P.C., Marlton, NJ, U.S.A.
  3. 3Department of Obstetrics and Gynecology, Philadelphia College of Osteopathic Medicine, Philadelphia, PA, U.S.A.
  1. Correspondence to: Jerome H. Check, MD, Ph.D., 7447 Old York Road, Melrose Park, PA 19027, U.S.A. Tel: +1 2156354156, Fax: +1 2156352304, e-mail: laurie{at}ccivf.com
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Anticancer Research: 34 (5)
Anticancer Research
Vol. 34, Issue 5
May 2014
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Evidence that Mifepristone, a Progesterone Receptor Antagonist, Can Cross the Blood Brain Barrier and Provide Palliative Benefits for Glioblastoma Multiforme Grade IV
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Evidence that Mifepristone, a Progesterone Receptor Antagonist, Can Cross the Blood Brain Barrier and Provide Palliative Benefits for Glioblastoma Multiforme Grade IV
JEROME H. CHECK, CARRIE WILSON, RACHAEL COHEN, MOJIRAYO SARUMI
Anticancer Research May 2014, 34 (5) 2385-2388;

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Evidence that Mifepristone, a Progesterone Receptor Antagonist, Can Cross the Blood Brain Barrier and Provide Palliative Benefits for Glioblastoma Multiforme Grade IV
JEROME H. CHECK, CARRIE WILSON, RACHAEL COHEN, MOJIRAYO SARUMI
Anticancer Research May 2014, 34 (5) 2385-2388;
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  • Palliative Benefits of Oral Mifepristone for the Treatment of Metastatic Fibroblastic Osteosarcoma
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  • Therapy Aimed to Suppress the Production of the Immunosuppressive Protein Progesterone Induced Blocking Factor (PIBF) May Provide Palliation and/or Increased Longevity for Patients With a Variety of Different Advanced Cancers - A Review
  • Mifepristone Extends Both Length and Quality of Life in a Patient With Advanced Non-small Cell Lung Cancer that Has Progressed Despite Chemotherapy and a Check-point Inhibitor
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Keywords

  • glioblastoma multiforme
  • blood–brain barrier
  • progesterone receptor antagonist
  • progesterone-induced blocking factor
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