Genetic and Epigenetic Aspects of Breast Cancer Progression and Therapy

SHANNON BYLER; SARAH GOLDGAR; SARAH HEERBOTH; MEGHAN LEARY; GENEVIEVE HOUSMAN; KIMBERLY MOULTON; SIBAJI SARKAR

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Genetic and Epigenetic Aspects of Breast Cancer Progression and Therapy

SHANNON BYLER, SARAH GOLDGAR, SARAH HEERBOTH, MEGHAN LEARY, GENEVIEVE HOUSMAN, KIMBERLY MOULTON and SIBAJI SARKAR

Anticancer Research March 2014, 34 (3) 1071-1077;

SHANNON BYLER

Cancer Center, Department of Medicine, Boston University School of Medicine, Boston, MA, U.S.A.

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SARAH GOLDGAR

Cancer Center, Department of Medicine, Boston University School of Medicine, Boston, MA, U.S.A.

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SARAH HEERBOTH

Cancer Center, Department of Medicine, Boston University School of Medicine, Boston, MA, U.S.A.

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MEGHAN LEARY

Cancer Center, Department of Medicine, Boston University School of Medicine, Boston, MA, U.S.A.

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GENEVIEVE HOUSMAN

Cancer Center, Department of Medicine, Boston University School of Medicine, Boston, MA, U.S.A.

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KIMBERLY MOULTON

Cancer Center, Department of Medicine, Boston University School of Medicine, Boston, MA, U.S.A.

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SIBAJI SARKAR

Cancer Center, Department of Medicine, Boston University School of Medicine, Boston, MA, U.S.A.

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For correspondence: ss1@bu.edu

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vol. 34 no. 3 1071-1077

PubMed

24596345

Published By

International Institute of Anticancer Research

Print ISSN

0250-7005

Online ISSN

1791-7530

History

Received December 20, 2013
Revision received January 13, 2014
Accepted January 14, 2014
Published online March 4, 2014.

Author Information

SHANNON BYLER,
SARAH GOLDGAR,
SARAH HEERBOTH,
MEGHAN LEARY,
GENEVIEVE HOUSMAN*,
KIMBERLY MOULTON and
SIBAJI SARKAR⇑

Cancer Center, Department of Medicine, Boston University School of Medicine, Boston, MA, U.S.A.

Correspondence to: Sibaji Sarkar, Cancer Center, L913, Department of Medicine, Boston University School of Medicine, 72 E Concord St, Boston, MA 02118, U.S.A. Tel: +1 6176385630, Fax: +1 6176385609, e-mail: ss1{at}bu.edu

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Anticancer Research

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March 2014

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Genetic and Epigenetic Aspects of Breast Cancer Progression and Therapy

SHANNON BYLER, SARAH GOLDGAR, SARAH HEERBOTH, MEGHAN LEARY, GENEVIEVE HOUSMAN, KIMBERLY MOULTON, SIBAJI SARKAR

Anticancer Research Mar 2014, 34 (3) 1071-1077;

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Genetic and Epigenetic Aspects of Breast Cancer Progression and Therapy

SHANNON BYLER, SARAH GOLDGAR, SARAH HEERBOTH, MEGHAN LEARY, GENEVIEVE HOUSMAN, KIMBERLY MOULTON, SIBAJI SARKAR

Anticancer Research Mar 2014, 34 (3) 1071-1077;

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Keywords

Breast cancer
Cancer
mutation
gene copy number
epigenetics
histone modification
histone deacetylase inhibitors
methylation
de-methylation
oncogene
tumor suppressor genes
metastasis
cancer progenitor cells
breast cancer progression
epithelial-mesenchymal transition (EMT)
therapeutics
combination therapy
drug resistance
review

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