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Research ArticleExperimental Studies

Magnolol Affects Expression of IGF-1 and Associated Binding Proteins in Human Prostate Cancer Cells In Vitro

BRENDAN T. McKEOWN and ROBERT A. R. HURTA
Anticancer Research November 2014, 34 (11) 6333-6338;
BRENDAN T. McKEOWN
Department of Biology, University of Prince Edward Island, Charlottetown, PE, Canada
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ROBERT A. R. HURTA
Department of Biology, University of Prince Edward Island, Charlottetown, PE, Canada
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  • For correspondence: rhurta@upei.ca
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    Figure 1.

    Magnolol affects expression of IGF-1 and associated proteins in PC3 human prostate cancer cells in vitro. Cells were treated with either dimethyl sulfoxide (DMSO) as control (Ctrl) or 80 μM magnolol for 6 h. Actin was used as a loading control. Each blot shown in Figure 1A is representative of results obtained from three separate experiments, each assayed at least in triplicate. These collective results are represented as changes in protein expression in the bar graphs in Figure 1B. (*) indicates statistical significance at p≤0.1 and (**) indicates statistical significance at p≤0.05.

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    Figure 2.

    Magnolol affects expression of IGF-1 and associated proteins in LNCaP human prostate cancer cells in vitro. Cells were treated with either dimethyl sulfoxide (DMSO) as control (Ctrl) or 80 μM magnolol for 6 h. Actin was used as a loading control. Each blot shown in Figure 2A is representative of results obtained from three separate experiments, each assayed as least in triplicate. These collective results are represented as changes in protein expression in the bar graphs in Figure 2B. (*) indicates statistical significance at p≤0.1 and (**) indicates statistical significance at p≤0.05.

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Anticancer Research: 34 (11)
Anticancer Research
Vol. 34, Issue 11
November 2014
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Magnolol Affects Expression of IGF-1 and Associated Binding Proteins in Human Prostate Cancer Cells In Vitro
BRENDAN T. McKEOWN, ROBERT A. R. HURTA
Anticancer Research Nov 2014, 34 (11) 6333-6338;

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Magnolol Affects Expression of IGF-1 and Associated Binding Proteins in Human Prostate Cancer Cells In Vitro
BRENDAN T. McKEOWN, ROBERT A. R. HURTA
Anticancer Research Nov 2014, 34 (11) 6333-6338;
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Keywords

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