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Review ArticleProceedings of the XI International Symposium of Platinum Coordination Compounds in Cancer Chemotherapy, 11-14 October 2012, Verona, ItalyR

Understanding and Improving Platinum Anticancer Drugs – Phenanthriplatin

TIMOTHY C. JOHNSTONE, GA YOUNG PARK and STEPHEN J. LIPPARD
Anticancer Research January 2014, 34 (1) 471-476;
TIMOTHY C. JOHNSTONE
1Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, U.S.A.
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GA YOUNG PARK
1Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, U.S.A.
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STEPHEN J. LIPPARD
1Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, U.S.A.
2Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, U.S.A.
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  • For correspondence: lippard@mit.edu
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Article Information

vol. 34 no. 1 471-476
PubMed 
24403503

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received October 8, 2013
  • Revision received November 25, 2013
  • Accepted November 27, 2013
  • Published online January 8, 2014.

Copyright & Usage 
Copyright© 2014 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved

Author Information

  1. TIMOTHY C. JOHNSTONE1,
  2. GA YOUNG PARK1 and
  3. STEPHEN J. LIPPARD1,2,*⇑
  1. 1Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, U.S.A.
  2. 2Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, U.S.A.
  1. Correspondence to: Stephen J. Lippard, Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Av., Cambridge, MA, 02139, U.S.A. Tel: +1 6172531848, e-mail: lippard{at}mit.edu
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Anticancer Research: 34 (1)
Anticancer Research
Vol. 34, Issue 1
January 2014
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Understanding and Improving Platinum Anticancer Drugs – Phenanthriplatin
TIMOTHY C. JOHNSTONE, GA YOUNG PARK, STEPHEN J. LIPPARD
Anticancer Research Jan 2014, 34 (1) 471-476;

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Understanding and Improving Platinum Anticancer Drugs – Phenanthriplatin
TIMOTHY C. JOHNSTONE, GA YOUNG PARK, STEPHEN J. LIPPARD
Anticancer Research Jan 2014, 34 (1) 471-476;
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  • Article
    • Abstract
    • Cisplatin and the Structure–Activity Relationships
    • Mechanism of Action of Classical Platinum Agents
    • Unconventional Platinum Anticancer Agents
    • Phenanthriplatin – A Potent Monofunctional Compound
    • Concluding Remarks
    • Acknowledgements
    • Footnotes
    • References
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More in this TOC Section

  • Biography of Professor Barnett Rosenberg: A Tribute to His Life and His Achievements
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  • Oxoglaucine-Lanthanide Complexes: Synthesis, Crystal Structure and Cytotoxicity
Show more Proceedings of the XI International Symposium of Platinum Coordination Compounds in Cancer Chemotherapy, 11-14 October 2012, Verona, Italy

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Keywords

  • cytotoxicity
  • transcription
  • RNA polymerase II
  • X-ray structure
  • monofunctional platinum
  • pyriplatin
  • review
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