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Research ArticleExperimental Studies

Evaluation of Cytotoxiciy and Tumor-specificity of Licorice Flavonoids Based on Chemical Structure

HIROKAZU OHNO, DAISUKE ARAHO, YOSHIHIRO UESAWA, HAJIME KAGAYA, MARIKO ISHIHARA, HIROSHI SAKAGAMI and MASAJI YAMAMOTO
Anticancer Research August 2013, 33 (8) 3061-3068;
HIROKAZU OHNO
1Maruzen Pharmaceuticals Co., Ltd., Shibuya, Tokyo, Japan
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  • For correspondence: h-ohno{at}maruzenpcy.co.jp
DAISUKE ARAHO
1Maruzen Pharmaceuticals Co., Ltd., Shibuya, Tokyo, Japan
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YOSHIHIRO UESAWA
2Department of Clinical Pharmaceutics, Meiji Pharmaceutical University, Kiyose, Tokyo, Japan
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HAJIME KAGAYA
2Department of Clinical Pharmaceutics, Meiji Pharmaceutical University, Kiyose, Tokyo, Japan
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MARIKO ISHIHARA
3Division of Basic Chemistry, Meikai University School of Dentistry, Sakado, Saitama, Japan
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HIROSHI SAKAGAMI
4Division of Pharmacology, Meikai University School of Dentistry, Sakado, Saitama, Japan
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MASAJI YAMAMOTO
1Maruzen Pharmaceuticals Co., Ltd., Shibuya, Tokyo, Japan
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Article Information

vol. 33 no. 8 3061-3068
PMID 
23898061

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received June 5, 2013
  • Revision received June 24, 2013
  • Accepted June 26, 2013
  • Published online July 29, 2013.

Copyright & Usage 
Copyright© 2013 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved

Author Information

  1. HIROKAZU OHNO1⇑,
  2. DAISUKE ARAHO1,
  3. YOSHIHIRO UESAWA2,
  4. HAJIME KAGAYA2,
  5. MARIKO ISHIHARA3,
  6. HIROSHI SAKAGAMI4 and
  7. MASAJI YAMAMOTO1
  1. 1Maruzen Pharmaceuticals Co., Ltd., Shibuya, Tokyo, Japan
  2. 2Department of Clinical Pharmaceutics, Meiji Pharmaceutical University, Kiyose, Tokyo, Japan
  3. 3Division of Basic Chemistry, Meikai University School of Dentistry, Sakado, Saitama, Japan
  4. 4Division of Pharmacology, Meikai University School of Dentistry, Sakado, Saitama, Japan
  1. Correspondence to: Hirokazu Ohno, Maruzen Pharmaceuticals 2-6-7 Ebisunishi, Shibuya, Tokyo, 150-0021, Japan. Tel: +81 334961521, Fax: +81 334961641, e-mail: h-ohno{at}maruzenpcy.co.jp
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August 2013
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Evaluation of Cytotoxiciy and Tumor-specificity of Licorice Flavonoids Based on Chemical Structure
HIROKAZU OHNO, DAISUKE ARAHO, YOSHIHIRO UESAWA, HAJIME KAGAYA, MARIKO ISHIHARA, HIROSHI SAKAGAMI, MASAJI YAMAMOTO
Anticancer Research Aug 2013, 33 (8) 3061-3068;

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Evaluation of Cytotoxiciy and Tumor-specificity of Licorice Flavonoids Based on Chemical Structure
HIROKAZU OHNO, DAISUKE ARAHO, YOSHIHIRO UESAWA, HAJIME KAGAYA, MARIKO ISHIHARA, HIROSHI SAKAGAMI, MASAJI YAMAMOTO
Anticancer Research Aug 2013, 33 (8) 3061-3068;
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Keywords

  • Licorice flavonoids
  • QSAR
  • cytotoxicity
  • tumor-specificity index
  • chemical descriptor
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