Lack of Association of Proteinuria and Clinical Outcome in Patients Treated with Bevacizumab for Metastatic Colorectal Cancer

SATORU IWASA; TAKAKO EGUCHI NAKAJIMA; KENGO NAGASHIMA; YOSHITAKA HONMA; KEN KATO; TETSUYA HAMAGUCHI; YASUHIDE YAMADA; YASUHIRO SHIMADA

Research ArticleClinical Studies

Lack of Association of Proteinuria and Clinical Outcome in Patients Treated with Bevacizumab for Metastatic Colorectal Cancer

SATORU IWASA, TAKAKO EGUCHI NAKAJIMA, KENGO NAGASHIMA, YOSHITAKA HONMA, KEN KATO, TETSUYA HAMAGUCHI, YASUHIDE YAMADA and YASUHIRO SHIMADA

Anticancer Research January 2013, 33 (1) 309-316;

SATORU IWASA

1Gastrointestinal Oncology Division, National Cancer Center Hospital, Tokyo, Japan

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TAKAKO EGUCHI NAKAJIMA

1Gastrointestinal Oncology Division, National Cancer Center Hospital, Tokyo, Japan

2Department of Clinical Oncology, St. Marianna University, School of Medicine, Kanagawa, Japan

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For correspondence: tnakajima{at}marianna-u.ac.jp

KENGO NAGASHIMA

3Laboratory of Biostatistics, Faculty of Pharmaceutical Sciences, Josai University, Saitama, Japan

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YOSHITAKA HONMA

1Gastrointestinal Oncology Division, National Cancer Center Hospital, Tokyo, Japan

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KEN KATO

1Gastrointestinal Oncology Division, National Cancer Center Hospital, Tokyo, Japan

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TETSUYA HAMAGUCHI

1Gastrointestinal Oncology Division, National Cancer Center Hospital, Tokyo, Japan

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YASUHIDE YAMADA

1Gastrointestinal Oncology Division, National Cancer Center Hospital, Tokyo, Japan

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YASUHIRO SHIMADA

1Gastrointestinal Oncology Division, National Cancer Center Hospital, Tokyo, Japan

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Figure 1.
Time of onset of proteinuria after bevacizumab therapy.
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Figure 2.
Kaplan–Meier estimates of progression-free survival for patients with grade 0-2 proteinuria.
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Figure 3.
Kaplan–Meier estimates of overall survival for patients with grade 0-2 proteinuria.

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Anticancer Research

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January 2013

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Lack of Association of Proteinuria and Clinical Outcome in Patients Treated with Bevacizumab for Metastatic Colorectal Cancer

SATORU IWASA, TAKAKO EGUCHI NAKAJIMA, KENGO NAGASHIMA, YOSHITAKA HONMA, KEN KATO, TETSUYA HAMAGUCHI, YASUHIDE YAMADA, YASUHIRO SHIMADA

Anticancer Research Jan 2013, 33 (1) 309-316;

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Lack of Association of Proteinuria and Clinical Outcome in Patients Treated with Bevacizumab for Metastatic Colorectal Cancer

SATORU IWASA, TAKAKO EGUCHI NAKAJIMA, KENGO NAGASHIMA, YOSHITAKA HONMA, KEN KATO, TETSUYA HAMAGUCHI, YASUHIDE YAMADA, YASUHIRO SHIMADA

Anticancer Research Jan 2013, 33 (1) 309-316;

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Keywords

bevacizumab
Colorectal cancer
predictive marker
proteinuria

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