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Research ArticleClinical Studies

Apoptosis-related Biomarkers sFAS, MIF, ICAM-1 and PAI-1 in Serum of Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy

DEBORA M.I. FERSCHING, DOROTHEA NAGEL, BARBARA SIEGELE, CHRISTOPH SALAT, VOLKER HEINEMANN, STEFAN HOLDENRIEDER and OLIVER J. STOETZER
Anticancer Research May 2012, 32 (5) 2047-2058;
DEBORA M.I. FERSCHING
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DOROTHEA NAGEL
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BARBARA SIEGELE
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CHRISTOPH SALAT
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VOLKER HEINEMANN
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STEFAN HOLDENRIEDER
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  • For correspondence: Stefan.Holdenrieder@uni-bonn.de
OLIVER J. STOETZER
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    Figure 1.

    Value distribution and medians of serum levels of soluble cell death receptor sFAS (A), macrophage migration-inhibitory factor (MIF) (B), soluble intercellular adhesion molecule (sICAM) (C) and plasminogen activator inhibitor 1 (PAI-1) (D) in healthy persons, patients with benign breast diseases, patients with locally confined breast cancer and patients with metastasized breast cancer.

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    Figure 2.

    Receiver operating characteristic (ROC) curves for the discrimination between patients with locally confined breast cancer and healthy controls (A), as well as between patients with metastatic breast cancer and all other controls (B).

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    Figure 3.

    Receiver operating characteristic (ROC) curves for the discrimination between patients with response and those with no response to neoadjuvant chemotherapy. Setting 1: NC versus CR+PR (A); Setting 2: NC+PR versus CR (B).

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Anticancer Research: 32 (5)
Anticancer Research
Vol. 32, Issue 5
May 2012
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Apoptosis-related Biomarkers sFAS, MIF, ICAM-1 and PAI-1 in Serum of Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy
DEBORA M.I. FERSCHING, DOROTHEA NAGEL, BARBARA SIEGELE, CHRISTOPH SALAT, VOLKER HEINEMANN, STEFAN HOLDENRIEDER, OLIVER J. STOETZER
Anticancer Research May 2012, 32 (5) 2047-2058;

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Apoptosis-related Biomarkers sFAS, MIF, ICAM-1 and PAI-1 in Serum of Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy
DEBORA M.I. FERSCHING, DOROTHEA NAGEL, BARBARA SIEGELE, CHRISTOPH SALAT, VOLKER HEINEMANN, STEFAN HOLDENRIEDER, OLIVER J. STOETZER
Anticancer Research May 2012, 32 (5) 2047-2058;
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