Table of Contents

Clinical Studies

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  A Phase I Study to Determine the Safety and Pharmacokinetics of Intravenous Administration of TAS-106 Once per Week for Three Consecutive Weeks Every 28 Days in Patients with Solid Tumors

  BENJAMIN FRIDAY, YVONNE LASSERE, CHRISTINA A. MEYERS, AKIRA MITA, JAMES L. ABBRUZZESE and MELANIE B. THOMAS

  Anticancer Research May 2012, 32 (5) 1689-1696;
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  Olfactory Neuroblastoma: 15 Years of Experience

  NORIO KONDO, HIDEAKI TAKAHASHI, YOKO NII and JUNICHI NAGAO

  Anticancer Research May 2012, 32 (5) 1697-1703;
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  Utility of Insulin-like Growth Factor Receptor-1 Expression in Gefitinib-Treated Patients with Non-small Cell Lung Cancer

  MARY JO FIDLER, SANJIB BASU, LELA BUCKINGHAM, KELLY WALTERS, SHARON MCCORMACK, MARTA BATUS, JOHN COON and PHILIP BONOMI

  Anticancer Research May 2012, 32 (5) 1705-1710;
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  Classification of Gastritis in First-degree Relatives of Patients with Gastric Cancer in a High Cancer-risk Area in Italy

  CALOGERO SAIEVA, CARLOS A. RUBIO, GABRIELLA NESI, ENZO ZINI and ALESSANDRO FILOMENA

  Anticancer Research May 2012, 32 (5) 1711-1716;
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  Metastasis to the Penis from Rectal Adenocarcinoma

  FORRESTALL DORSETT, JACK HOU and OLEG SHAPIRO

  Anticancer Research May 2012, 32 (5) 1717-1719;
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  Oncological Short-term Effects and Adverse Events of MRI-guided Selective Neoadjuvant Radiochemotherapy for Rectal Cancer

  C.A. MAURER, D. MATTIELLO, J. DUWE, R. RUPPERT, H. PTOK, J. STRASSBURG, T. JUNGINGER, S. MERKEL and P. HERMANEK

  Anticancer Research May 2012, 32 (5) 1721-1728;
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  Presurgical Treatment with Sunitinib for Renal Cell Carcinoma with a Level III/IV Vena Cava Tumour Thrombus

  THOMAS HORN, MARK K. THALGOTT, TOBIAS MAURER, KATHARINA HAUNER, STEPHAN SCHULZ, ALEXANDER FINGERLE, MARGITTA RETZ, JÜRGEN E. GSCHWEND and HUBERT R. KÜBLER

  Anticancer Research May 2012, 32 (5) 1729-1735;
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  Vaginal Fistula in a Patient with Relapsed Ovarian Cancer and Amelanotic Melanoma

  MUSTAFA ZELAL MUALLEM, SULE YILDIZ, RUZA ARSENIC, UWE TREFZER and JALID SEHOULI

  Anticancer Research May 2012, 32 (5) 1737-1742;
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  Survival of a Patient with Anaplastic Thyroid Cancer Following Intensity-modulated Radiotherapy and Sunitinib - A Case Report

  JONATHAN D. SCHOENFELD, OREOFE O. ODEJIDE, LORI J. WIRTH and ANNIE W. CHAN

  Anticancer Research May 2012, 32 (5) 1743-1746;
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  Decrease of CD44-positive Cells Correlates with Tumor Response to Chemotherapy in Patients with Gastrointestinal Cancer

  VINDHYA PALAGANI, MONA EL KHATIB, TILL KRECH, MICHAEL P. MANNS, NISAR P. MALEK and RUBEN R. PLENTZ

  Anticancer Research May 2012, 32 (5) 1747-1755;
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  Expression Levels of Thymidylate Synthase, Dihydropyrimidine Dehydrogenase, and Thymidine Phosphorylase in Patients with Colorectal Cancer

  TETSUHIRO GOTO, KAZUKI SHINMURA, KAZUAKI YOKOMIZO, KAZUMA SAKURABA, YOUHEI KITAMURA, ATSUSHI SHIRAHATA, MITSUO SAITO, GAKU KIGAWA, HIROSHI NEMOTO, YUTAKA SANADA and KENJI HIBI

  Anticancer Research May 2012, 32 (5) 1757-1762;
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  The Relationship Between Antitumor Effects and Relative Dose Intensity of S-1 plus Cisplatin Treatment for Metastatic Gastric Cancer

  MIKA KITAGAWA, TAKAYA SHIMURA, TOMONORI YAMADA, MASAHIDE EBI, YOSHIKAZU HIRATA, TSUTOMU MIZOSHITA, SATOSHI TANIDA, HIROMI KATAOKA, TAKESHI KAMIYA and TAKASHI JOH

  Anticancer Research May 2012, 32 (5) 1763-1768;
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  Serum Pharmacokinetics in Patients Treated with Transarterial Chemoembolization (TACE) Using Two Types of Epirubicin-loaded Microspheres

  CRISTINA SOTTANI, GUIDO POGGI, PIETRO QUARETTI, MARIO REGAZZI, BENEDETTA MONTAGNA, ERICA QUAQUARINI, MARCELLO IMBRIANI, EMANUELA LEONI, PAMELA DI CESARE, ALBERTO RICCARDI, GIOVANNI BERNARDO and CLAUDIO MINOIA

  Anticancer Research May 2012, 32 (5) 1769-1774;
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  A KIT-negative, DOG1-positive Epithelioid GIST of the Stomach Harboring a Novel PDGFRA Exon 14 Single Nucleotide Deletion

  CLARA RIZZARDI, STEFANIA MARZINOTTO, CLAUDIO AVELLINI, MAURO MELATO and LAURA MARIUZZI

  Anticancer Research May 2012, 32 (5) 1775-1778;
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  T315I Mutation in Ph-positive Acute Lymphoblastic Leukemia is Associated with a Highly Aggressive Disease Phenotype: Three Case Reports

  KEISUKE WATANABE, YOSUKE MINAMI, YUKIYASU OZAWA, KOICHI MIYAMURA and TOMOKI NAOE

  Anticancer Research May 2012, 32 (5) 1779-1783;
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  Airway Stenting for Malignant Respiratory Complications in Esophageal Cancer

  YOICHI HAMAI, JUN HIHARA, MANABU EMI, YOSHIRO AOKI, YOSHIHIRO MIYATA and MORIHITO OKADA

  Anticancer Research May 2012, 32 (5) 1785-1790;
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  The Interplay between Hemostasis and Malignancy: The Oral Cancer Paradigm

  CHRISTOS YAPIJAKIS, ATHANASIOS BRAMOS, ALEXANDER MICHAEL NIXON, VASSILIS RAGOS and ELEFTHERIOS VAIRAKTARIS

  Anticancer Research May 2012, 32 (5) 1791-1800;
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  Serum Amyloid A: a Biomarker for Renal Cancer

  KERSTEN FISCHER, GERIT THEIL, RASCHID HODA and PAOLO FORNARA

  Anticancer Research May 2012, 32 (5) 1801-1804;
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  Pilot Study of Duloxetine for Cancer Patients with Neuropathic Pain Non-responsive to Pregabalin

  HIROMICHI MATSUOKA, CHIHIRO MAKIMURA, ATSUKO KOYAMA, MASATOMO OTSUKA, WATARU OKAMOTO, YASUHITO FUJISAKA, HIROYASU KANEDA, JUNJI TSURUTANI and KAZUHIKO NAKAGAWA

  Anticancer Research May 2012, 32 (5) 1805-1809;
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  Prognostic Factors and Clinical Outcome of Patients with Lung Adenocarcinoma with Carcinomatous Meningitis

  YUKIKO NAKAMURA, TOSHIAKI TAKAHASHI, ASUKA TSUYA, TATEAKI NAITO, HIROTSUGU KENMOTSU, AKIRA ONO, TAKEHITO SHUKUYA, HARUYASU MURAKAMI, HIDEAKI HARADA, REIKO WATANABE, MASAHIRO ENDO, KOICHI MITSUYA, TAKASHI NAKAJIMA and NOBUYUKI YAMAMOTO

  Anticancer Research May 2012, 32 (5) 1811-1816;
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  Patient Age and Biological Aggressiveness of Endometrial Carcinoma

  I. GONZALEZ-RODILLA, M. BOIX, V. VERNA, A.B. MUÑOZ, J. ESTÉVEZ, Y. JUBETE and J. SCHNEIDER

  Anticancer Research May 2012, 32 (5) 1817-1820;
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  Treatment Strategies for Well-differentiated Liposarcomas and Therapeutic Outcomes

  NORIO YAMAMOTO, KATSUHIRO HAYASHI, YOSHIKAZU TANZAWA, HIROAKI KIMURA, AKIHIKO TAKEUCHI, KENTARO IGARASHI, HIROYUKI INATANI, SHINGO SHIMOZAKI, SEIKO KITAMURA and HIROYUKI TSUCHIYA

  Anticancer Research May 2012, 32 (5) 1821-1825;
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  A Combined Therapy with Docetaxel and Nedaplatin for Relapsed and Metastatic Esophageal Carcinoma

  HIDEO MATSUMOTO, YOKO HIRABAYASHI, HISAKO KUBOTA, HARUAKI MURAKAMI, MASAHARU HIGASHIDA, KEN HARUMA, JUNICH HIRATSUKA, MASAFUMI NAKAMURA and TOSHIHIRO HIRAI

  Anticancer Research May 2012, 32 (5) 1827-1831;
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  Salvage Chemotherapy with Cisplatin and 5-Fluorouracil in Metastatic Breast Cancer. Particular Activity against Liver Metastases

  LAZAROS LEKAKIS, DIMITRIOS TRYFONOPOULOS, NIKOLAOS PISTAMATZIAN, CHRISTOS PANOPOULOS, GEORGE KOUMAKIS, STAMATINA DEMIRI and ANNA EFREMIDIS

  Anticancer Research May 2012, 32 (5) 1833-1837;
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  Evaluation of Important Prognostic Clinical and Pathological Factors in Gastric Cancer

  GREGOR CAMMERER, ANDREA FORMENTINI, MARKUS KARLETSHOFER, DORIS HENNE-BRUNS and MARKO KORNMANN

  Anticancer Research May 2012, 32 (5) 1839-1842;
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  ABSTRACTS OF THE 22nd ANNUAL MEETING OF THE ITALIAN SOCIETY OF URO-ONCOLOGY (SIUrO)

  Anticancer Research May 2012, 32 (5) 1843-1966;
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  PROCEEDINGS OF THE 15th INTERNATIONAL HAMBURG SYMPOSIUM ON TUMOR MARKERS

  Anticancer Research May 2012, 32 (5) 1967-1968;
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  Cytokeratin Serum Biomarkers in Patients with Colorectal Cancer

  S. HOLDENRIEDER, P. STIEBER, V. LISKA, V. TRESKA, O. TOPOLCAN, J. DRESLEROVA, V.M. MATEJKA, J. FINEK and L. HOLUBEC

  Anticancer Research May 2012, 32 (5) 1971-1976;
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  Chromosomal Rearrangements in PLAG1 of Myoepithelial Salivary Gland Tumours

  REINHARD E. FRIEDRICH, JULIA DILCHER, MICHAEL JAEHNE and THOMAS LÖNING

  Anticancer Research May 2012, 32 (5) 1977-1981;
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  Real-time Cell Analysis of Human Cancer Cell Lines after Chemotherapy with Functionalized Magnetic Nanoparticles

  STEPHAN DÜRR, STEFAN LYER, JENNY MANN, CHRISTINA JANKO, RAINER TIETZE, EVELINE SCHREIBER, MARTIN HERRMANN and CHRISTOPH ALEXIOU

  Anticancer Research May 2012, 32 (5) 1983-1989;
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  Vitamin D Status and Per-oral Vitamin D Supplementation in Patients Suffering from Chronic Pancreatitis and Pancreatic Cancer Disease

  S. KLAPDOR, E. RICHTER and R. KLAPDOR

  Anticancer Research May 2012, 32 (5) 1991-1998;
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  Surgery for Advanced and Metastatic Pancreatic Cancer – Current State and Trends

  MICHAEL F. NENTWICH, MAXIMILIAN BOCKHORN, ALEXANDRA KÖNIG, JAKOB R. IZBICKI and GÜLLÜ CATALDEGIRMEN

  Anticancer Research May 2012, 32 (5) 1999-2002;
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  Two-marker Combinations for Preoperative Discrimination of Benign and Malignant Ovarian Masses

  MAJ KRISTIN FREYDANCK, RUEDIGER PAUL LAUBENDER, BRIGITTE RACK, LAN SCHUHMACHER, UDO JESCHKE and CHRISTOPH SCHOLZ

  Anticancer Research May 2012, 32 (5) 2003-2008;
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  Circulating Microparticles in Patients with Benign and Malignant Ovarian Tumors

  A. RANK, S. LIEBHARDT, J. ZWIRNER, A. BURGES, R. NIEUWLAND and B. TOTH

  Anticancer Research May 2012, 32 (5) 2009-2014;
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  Comparative Analysis of Sensitivity to Blood in the Urine for Urine-based Point-of-Care Assays (UBC rapid, NMP22 BladderChek and BTA-stat) in Primary Diagnosis of Bladder Carcinoma. Interference of Blood on the Results of Urine-based POC Tests

  GERSON LÜDECKE, ADRIAN PILATZ, ARNE HAUPTMANN, THOMAS BSCHLEIPFER and WOLFGANG WEIDNER

  Anticancer Research May 2012, 32 (5) 2015-2018;
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  Expression of Podoplanin in Primary and Metastatic Poorly Differentiated and Undifferentiated Carcinomas of the Head and Neck

  REINHARD E. FRIEDRICH, SYLVA BARTEL-FRIEDRICH and CHRISTIAN HAGEL

  Anticancer Research May 2012, 32 (5) 2019-2022;
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  Expression of Different Carbohydrate Tumour Markers and Galectins 1 and 3 in Normal Squamous and Malignant Epithelia of the Upper Aaerodigestive Tract

  IRMI WIEST, CHRISTOPH ALEXIOU, CHRISTINA KUHN, SANDRA SCHULZE, SUSANNE KUNZE, DORIS MAYR, PETER BETZ, UDO JESCHKE and DARIUS DIAN

  Anticancer Research May 2012, 32 (5) 2023-2029;
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  Similar Incidences of TP53 Deletions in Extramedullary Organ Infiltrations, Soft Tissue and Osteolyses of Patients with Multiple Myeloma

  LISA BILLECKE, EVA MARIA MURGA PENAS, ANNETTE M. MAY, MONIKA ENGELHARDT, ARNON NAGLER, MERAV LEIBA, GINETTE SCHIBY, NICOLAUS KRÖGER, JOZEF ZUSTIN, ANDREAS MARX, JAKOB MATSCHKE, MARKUS TIEMANN, ERAY GOEKKURT, CARSTEN BOKEMEYER and GEORGIA SCHILLING

  Anticancer Research May 2012, 32 (5) 2031-2034;
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  PI3K Inhibitor D-116883 is Effective in In Vitro Models of Ovarian Cancer

  A. HONIG, J.C. HAHNE, S. MEYER, P. KRANKE, S. HÄUSLER, J. DIESSNER, J. DIETL and J.B. ENGEL

  Anticancer Research May 2012, 32 (5) 2035-2041;
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  Scattering Effects of Irradiation on Surroundings Calculated for a Small Dental Implant

  REINHARD E. FRIEDRICH, MANUEL TODOROVIC, MAX HEILAND, HANNA A. SCHEUER and ANDREAS KRÜLL

  Anticancer Research May 2012, 32 (5) 2043-2046;
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  Apoptosis-related Biomarkers sFAS, MIF, ICAM-1 and PAI-1 in Serum of Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy

  DEBORA M.I. FERSCHING, DOROTHEA NAGEL, BARBARA SIEGELE, CHRISTOPH SALAT, VOLKER HEINEMANN, STEFAN HOLDENRIEDER and OLIVER J. STOETZER

  Anticancer Research May 2012, 32 (5) 2047-2058;
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  Methodological and Preanalytical Evaluation of an HMGB1 Immunoassay

  JULIA LEHNER, CHRISTIN WITTWER, DEBORA FERSCHING, BARBARA SIEGELE, STEFAN HOLDENRIEDER and OLIVER J. STOETZER

  Anticancer Research May 2012, 32 (5) 2059-2062;
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  Peptidomimetic GnRH Antagonist AEZS-115 Inhibits the Growth of Ovarian and Endometrial Cancer Cells

  J.B. ENGEL, J.C. HAHNE, S.F.M. HÄUSLER, S. MEYER, S. E. SEGERER, J. DIESSNER, J. DIETL and A. HONIG

  Anticancer Research May 2012, 32 (5) 2063-2068;
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  Radiotherapy for Giant Cell Tumors of the Bone: A Safe and Effective Treatment Modality

  JAN KRIZ, HANS THEODOR EICH, RALPH MÜCKE, JENS BÜNTZEL, ROLF-PETER MÜLLER, FRANK BRUNS, M. HEINRICH SEEGENSCHMIEDT, GEORG GOSHEGER, OLIVER MICKE and for the German Cooperative Group on Radiotherapy for Benign Diseases (GCG-BD)

  Anticancer Research May 2012, 32 (5) 2069-2073;
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  Methodological and Preanalytical Evaluation of a RAGE Immunoassay

  CHRISTIN WITTWER, JULIA LEHNER, DEBORA FERSCHING, BARBARA SIEGELE, OLIVER J STOETZER and STEFAN HOLDENRIEDER

  Anticancer Research May 2012, 32 (5) 2075-2078;
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  Surgical and Oncological Outcomes in Patients with a Preoperative PSA Value <4 ng/ml Undergoing Robot-assisted Radical Prostatectomy

  VAHUDIN ZUGOR, APOSTOLOS P. LABANARIS, RICARDA M. BAUER and JORN H. WITT

  Anticancer Research May 2012, 32 (5) 2079-2083;
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  Robotic-assisted Radical Prostatectomy in Men ≥75 Years of Age. Surgical, Oncological and Functional Outcomes

  APOSTOLOS P. LABANARIS, JORN H. WITT and VAHUDIN ZUGOR

  Anticancer Research May 2012, 32 (5) 2085-2089;
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  Surgical and Oncological Outcomes in Patients with Preoperative PSA >20 ng/ml Undergoing Robot-assisted Radical Prostatectomy

  VAHUDIN ZUGOR, JORN H. WITT, AXEL HEIDENREICH, DANIEL PORRES and APOSTOLOS P. LABANARIS

  Anticancer Research May 2012, 32 (5) 2091-2095;
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  Robotic-assisted Radical Prostatectomy in Men ≤50 Years of Age. Surgical, Oncological and Functional Outcomes

  APOSTOLOS P. LABANARIS, VAHUDIN ZUGOR and JORN H. WITT

  Anticancer Research May 2012, 32 (5) 2097-2101;
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  Multiple Myeloma: Myeloablative Therapy with Autologous Stem Cell Support versus Chemotherapy: A Meta-analysis

  FLORIAN FAUSSNER and WOLFRAM C.M. DEMPKE

  Anticancer Research May 2012, 32 (5) 2103-2109;
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  Parenteral Nutrition Support for Patients with Pancreatic Cancer – Improvement of the Nutritional Status and the Therapeutic Outcome

  EVA RICHTER, ALMUT DENECKE, SILKE KLAPDOR and RAINER KLAPDOR

  Anticancer Research May 2012, 32 (5) 2111-2118;
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  Nutritional Parameters for Patients with Head and Neck Cancer

  JENS BÜNTZEL, TINA KRAUß, HEIKE BÜNTZEL, KLAUS KÜTTNER, DIETMAR FRÖHLICH, WOLFGANG OEHLER, MICHAEL GLATZEL, MATTHIAS WACKES, JENS PUTZIGER, OLIVER MICKE, KLAUS KISTERS and RALPH MÜCKE

  Anticancer Research May 2012, 32 (5) 2119-2123;
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  Expression of Podoplanin in Nevoid Basal Cell Carcinoma Syndrome-Associated Keratocystic Odontogenic Tumours

  REINHARD E. FRIEDRICH, HANNA A. SCHEUER and JOZEF ZUSTIN

  Anticancer Research May 2012, 32 (5) 2125-2127;
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  Infiltration of Colorectal Carcinoma by S100⁺ Dendritic Cells and CD57⁺ Lymphocytes as Independent Prognostic Factors after Radical Surgical Treatment

  VACLAV LISKA, ONDREJ VYCITAL, ONDREJ DAUM, PETR NOVAK, VLADISLAV TRESKA, JAN BRUHA, PAVEL PITULE and LUBOS HOLUBEC

  Anticancer Research May 2012, 32 (5) 2129-2132;
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  A Retrospective In Vitro Study of the Impact of Anti-diabetics and Cardioselective Pharmaceuticals on Breast Cancer

  M. SZEWCZYK, C. RICHTER, V. BRIESE and D.-U. RICHTER

  Anticancer Research May 2012, 32 (5) 2133-2138;
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  Vascular Wall Cells Contribute to Tumourigenesis in Cutaneous Neurofibromas of Patients with Neurofibromatosis Type 1. A Comparative Histological, Ultrastructural and Immunohistochemical Study

  REINHARD E. FRIEDRICH, ADOLF-FRIEDRICH HOLSTEIN, RALF MIDDENDORFF and MICHAIL S. DAVIDOFF

  Anticancer Research May 2012, 32 (5) 2139-2158;
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  Expression of the Tumor Markers Sialyl Lewis A, Sialyl Lewis X, Lewis Y, Thomsen-Friedenreich Antigen, Galectin-1 and Galectin-3 in Human Osteoblasts In Vitro

  J. TÜBEL, B. SALDAMLI, I. WIEST, U. JESCHKE and R. BURGKART

  Anticancer Research May 2012, 32 (5) 2159-2164;
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  Squamous Cell Carcinoma of the Sole of the Foot in Neurofibromatosis Type 1

  REINHARD E. FRIEDRICH, ACHMED AL-DAM and CHRISTIAN HAGEL

  Anticancer Research May 2012, 32 (5) 2165-2168;
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  Odontogenic Myxomas Are not Associated with GNAS1 Mutations

  REINHARD E. FRIEDRICH, HANNA A. SCHEUER, ALEXANDRE T. ASSAF, TOBIAS GROB and JOZEF ZUSTIN

  Anticancer Research May 2012, 32 (5) 2169-2172;
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  Radiographic Findings of Odontogenic Myxomas on Conventional Radiographs

  REINHARD E. FRIEDRICH, HANNA A. SCHEUER, ANDREAS FUHRMANN, JOZEF ZUSTIN and ALEXANDRE T. ASSAF

  Anticancer Research May 2012, 32 (5) 2173-2177;
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  Nature and Dynamics of Nucleosome Release from Neoplastic and Non-neoplastic Cells

  STEFAN HOLDENRIEDER, FRANK T. KOLLIGS, JAN BRAESS, DAVIT MANUKYAN and PETRA STIEBER

  Anticancer Research May 2012, 32 (5) 2179-2183;
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  Determination of MUC1 in Sera of Ovarian Cancer Patients and in Sera of Patients with Benign Changes of the Ovaries with CA15-3, CA27.29, and PankoMab

  UDO JESCHKE, IRMI WIEST, ANAMUR LAN SCHUMACHER, MARKUS KUPKA, BRIGITTE RACK, RENATE STAHN, UWE KARSTEN, DORIS MAYR, KLAUS FRIESE and DARIUS DIAN

  Anticancer Research May 2012, 32 (5) 2185-2189;
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  Combination Therapy with Gemcitabine (GEM) and Erlotinib (E) in Exocrine Pancreatic Cancer under Special Reference to RASH and the Tumour Marker CA19-9

  R. KLAPDOR, S. KLAPDOR and M. BAHLO

  Anticancer Research May 2012, 32 (5) 2191-2197;
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  Relevance of Histone Marks H3K9me3 and H4K20me3 in Cancer

  GLORIA LESZINSKI, UGUR GEZER, BARBARA SIEGELE, OLIVER STOETZER and STEFAN HOLDENRIEDER

  Anticancer Research May 2012, 32 (5) 2199-2205;
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  Size of Tooth Crowns and Position of Teeth Concerning the Extension of Facial Plexiform Neurofibroma in Patients with Neurofibromatosis Type 1

  REINHARD E. FRIEDRICH, MANFRED GIESE, CLAUDIA STELLJES, CHRISTINE FROEDER and HANNA A. SCHEUER

  Anticancer Research May 2012, 32 (5) 2207-2214;
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  Errata

  Anticancer Research May 2012, 32 (5) 2215;
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  Errata

  Anticancer Research May 2012, 32 (5) 2215;
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  Announcements

  Anticancer Research May 2012, 32 (5) 2224;