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Research ArticleClinical Studies

Daily 500 mg Valacyclovir Is Effective for Prevention of Varicella Zoster Virus Reactivation in Patients with Multiple Myeloma Treated with Bortezomib

TOSHIHIRO FUKUSHIMA, TOMOMI SATO, TAKUJI NAKAMURA, HARUKA IWAO, AKIO NAKAJIMA, MIYUKI MIKI, TOMOYUKI SAKAI, TAKAFUMI KAWANAMI, TOSHIOKI SAWAKI, YOSHIMASA FUJITA, MASAO TANAKA, YASUFUMI MASAKI, TOSHIRO OKAZAKI, HIDEO NAKAJIMA, YOSHIHARU MOTOO and HISANORI UMEHARA
Anticancer Research December 2012, 32 (12) 5437-5440;
TOSHIHIRO FUKUSHIMA
1Department of Hematology and Immunology, Kanazawa Medical University, Ishikawa, Japan
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  • For correspondence: tfukus{at}kanazawa-med.ac.jp
TOMOMI SATO
1Department of Hematology and Immunology, Kanazawa Medical University, Ishikawa, Japan
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TAKUJI NAKAMURA
1Department of Hematology and Immunology, Kanazawa Medical University, Ishikawa, Japan
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HARUKA IWAO
1Department of Hematology and Immunology, Kanazawa Medical University, Ishikawa, Japan
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AKIO NAKAJIMA
1Department of Hematology and Immunology, Kanazawa Medical University, Ishikawa, Japan
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MIYUKI MIKI
1Department of Hematology and Immunology, Kanazawa Medical University, Ishikawa, Japan
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TOMOYUKI SAKAI
1Department of Hematology and Immunology, Kanazawa Medical University, Ishikawa, Japan
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TAKAFUMI KAWANAMI
1Department of Hematology and Immunology, Kanazawa Medical University, Ishikawa, Japan
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TOSHIOKI SAWAKI
1Department of Hematology and Immunology, Kanazawa Medical University, Ishikawa, Japan
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YOSHIMASA FUJITA
1Department of Hematology and Immunology, Kanazawa Medical University, Ishikawa, Japan
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MASAO TANAKA
1Department of Hematology and Immunology, Kanazawa Medical University, Ishikawa, Japan
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YASUFUMI MASAKI
1Department of Hematology and Immunology, Kanazawa Medical University, Ishikawa, Japan
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TOSHIRO OKAZAKI
1Department of Hematology and Immunology, Kanazawa Medical University, Ishikawa, Japan
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HIDEO NAKAJIMA
2Department of Medical Oncology, Kanazawa Medical University, Ishikawa, Japan
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YOSHIHARU MOTOO
2Department of Medical Oncology, Kanazawa Medical University, Ishikawa, Japan
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HISANORI UMEHARA
1Department of Hematology and Immunology, Kanazawa Medical University, Ishikawa, Japan
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Article Information

vol. 32 no. 12 5437-5440
PMID 
23225448

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received August 27, 2012
  • Revision received October 10, 2012
  • Accepted October 11, 2012
  • Published online December 6, 2012.

Copyright & Usage 
Copyright© 2012 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved

Author Information

  1. TOSHIHIRO FUKUSHIMA1⇓,
  2. TOMOMI SATO1,
  3. TAKUJI NAKAMURA1,
  4. HARUKA IWAO1,
  5. AKIO NAKAJIMA1,
  6. MIYUKI MIKI1,
  7. TOMOYUKI SAKAI1,
  8. TAKAFUMI KAWANAMI1,
  9. TOSHIOKI SAWAKI1,
  10. YOSHIMASA FUJITA1,
  11. MASAO TANAKA1,
  12. YASUFUMI MASAKI1,
  13. TOSHIRO OKAZAKI1,
  14. HIDEO NAKAJIMA2,
  15. YOSHIHARU MOTOO2 and
  16. HISANORI UMEHARA1
  1. 1Department of Hematology and Immunology, Kanazawa Medical University, Ishikawa, Japan
  2. 2Department of Medical Oncology, Kanazawa Medical University, Ishikawa, Japan
  1. Correspondence to: Toshihiro Fukushima, MD, Ph.D., Department of Hematology and Immunology, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Ishikawa 920-0293, Japan. Tel: +81 762862211, Fax: +81 762869290, e-mail: tfukus{at}kanazawa-med.ac.jp
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December 2012
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Daily 500 mg Valacyclovir Is Effective for Prevention of Varicella Zoster Virus Reactivation in Patients with Multiple Myeloma Treated with Bortezomib
TOSHIHIRO FUKUSHIMA, TOMOMI SATO, TAKUJI NAKAMURA, HARUKA IWAO, AKIO NAKAJIMA, MIYUKI MIKI, TOMOYUKI SAKAI, TAKAFUMI KAWANAMI, TOSHIOKI SAWAKI, YOSHIMASA FUJITA, MASAO TANAKA, YASUFUMI MASAKI, TOSHIRO OKAZAKI, HIDEO NAKAJIMA, YOSHIHARU MOTOO, HISANORI UMEHARA
Anticancer Research Dec 2012, 32 (12) 5437-5440;

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Daily 500 mg Valacyclovir Is Effective for Prevention of Varicella Zoster Virus Reactivation in Patients with Multiple Myeloma Treated with Bortezomib
TOSHIHIRO FUKUSHIMA, TOMOMI SATO, TAKUJI NAKAMURA, HARUKA IWAO, AKIO NAKAJIMA, MIYUKI MIKI, TOMOYUKI SAKAI, TAKAFUMI KAWANAMI, TOSHIOKI SAWAKI, YOSHIMASA FUJITA, MASAO TANAKA, YASUFUMI MASAKI, TOSHIRO OKAZAKI, HIDEO NAKAJIMA, YOSHIHARU MOTOO, HISANORI UMEHARA
Anticancer Research Dec 2012, 32 (12) 5437-5440;
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  • Importance of Compliance With Guidelines for the Prevention of Varicella-Zoster Virus Reactivation in Multiple Myeloma
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  • Bortezomib-Induced Unfolded Protein Response Increases Oncolytic HSV-1 Replication Resulting in Synergistic Antitumor Effects
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Keywords

  • multiple myeloma
  • Bortezomib
  • varicella zoster virus
  • valacyclovir
  • acyclovir
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