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Research ArticleExperimental Studies

Combination of Glucan, Resveratrol and Vitamin C Demonstrates Strong Anti-tumor Potential

VACLAV VETVICKA and JANA VETVICKOVA
Anticancer Research January 2012, 32 (1) 81-87;
VACLAV VETVICKA
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  • For correspondence: vaclav.vetvicka@louisville.edu
JANA VETVICKOVA
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This article has corrections. Please see:

  • Errata - February 01, 2012
  • Errata - February 01, 2012

Abstract

β-Glucans are naturally occurring carbohydrates found in plants, fungi and some bacterial species, and currently are well-established and powerful immunomodulators with beneficial properties in cancer therapy. Recent studies suggested that some additional bioactive molecules have synergistic effects when combined with glucan. In the current study, we evaluated the anticancer properties of glucan, resveratrol, vitamin C combination. We found that compared to the individual components, the combination was the strongest activator of phagocytosis and antibody formation. Using two different models of cancer treatment, our results demonstrated that the combination strongly suppressed the growth of breast and lung tumors, most likely due to the stimulation of apoptosis.

  • Glucan
  • resveratrol
  • vitamin C
  • cancer
  • immunity
  • phagocytosis
  • Received October 25, 2011.
  • Revision received November 28, 2011.
  • Accepted November 30, 2011.
  • Copyright© 2012 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved
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Anticancer Research: 32 (1)
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January 2012
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Combination of Glucan, Resveratrol and Vitamin C Demonstrates Strong Anti-tumor Potential
VACLAV VETVICKA, JANA VETVICKOVA
Anticancer Research Jan 2012, 32 (1) 81-87;

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Combination of Glucan, Resveratrol and Vitamin C Demonstrates Strong Anti-tumor Potential
VACLAV VETVICKA, JANA VETVICKOVA
Anticancer Research Jan 2012, 32 (1) 81-87;
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