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Research ArticleExperimental Studies

Alpha Terpineol: A Potential Anticancer Agent which Acts through Suppressing NF-κB Signalling

SAADIA BASHIR HASSAN, HALA GALI-MUHTASIB, HANNA GÖRANSSON and ROLF LARSSON
Anticancer Research June 2010, 30 (6) 1911-1919;
SAADIA BASHIR HASSAN
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  • For correspondence: sadia.hassan@medsci.uu.se
HALA GALI-MUHTASIB
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HANNA GÖRANSSON
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ROLF LARSSON
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    Figure 1.

    Dose-response curves showing the effect of alpha terpineol in six of the 14 human tumour cell lines tested in this study as assayed by the FMCA. Data from 3 experiments are represented as mean±SEM.

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    Figure 2.

    Cell cycle regulation in the lymphoma cells, U937-GTB, induced by 3 mM (b and e) and 6 mM (c and f) alpha terpineol at 6h (b and c) and 24h (e and f) using the LSR II flow cytometer. ModFit LT software was used to analyse the percentage of the cells in different cell cycle phases. (a and d) are the control cell cycle profiles of U937-GTB lymphoma cells, at 6h and 24h, respectively.

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    Figure 3.

    Effect of different concentrations of alpha terpineol on: (a) TNFα-induced NF-κB translocation and percentage of surviving, human cervix (Hela) cells and (b) the intracellular status of NF-κB, activated with TNF-α, in the human cervical cell line, beta-lactamase reporter gene-ME-180. Data for cell survival are represented as the mean±SEM.

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Anticancer Research: 30 (6)
Anticancer Research
Vol. 30, Issue 6
June 2010
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Alpha Terpineol: A Potential Anticancer Agent which Acts through Suppressing NF-κB Signalling
SAADIA BASHIR HASSAN, HALA GALI-MUHTASIB, HANNA GÖRANSSON, ROLF LARSSON
Anticancer Research Jun 2010, 30 (6) 1911-1919;

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Alpha Terpineol: A Potential Anticancer Agent which Acts through Suppressing NF-κB Signalling
SAADIA BASHIR HASSAN, HALA GALI-MUHTASIB, HANNA GÖRANSSON, ROLF LARSSON
Anticancer Research Jun 2010, 30 (6) 1911-1919;
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