Article Figures & Data
Figures
- Figure 1.
Structures of coumarin (compound 1), 7-hydroxycoumarin (compound 2), coumarin-based benzopyranone derivatives containing basic sides chain (compound 3) and tamoxifen (TAM, compound 4).
- Figure 2.
Effect of compound 9 on A549 viability. The cells at a initial density of 1.0×104 per well were treated with 0, 10, 25, 50, 75 or 100 μM of the compound in a final volume of 1 ml F12K complete medium containing 10% FCS for 24 h or 48 h. Data are represented as the mean (boxes) and SEM (errorbars) for n=3. *Statistically significant difference from the control (p<0.05) using Dunnett's multiple comparison test.
- Figure 3.
Effect of compound 9 on A549 cell cycle. The cells at an initial density of 1.3×106/ml per T-25 flask in F12K complete medium containing 10% FCS were treated with 0, 10, 25 or 50 μM of the compound for 24 h. Cells were pelleted and stained by propidium iodide staining solution for 1 h in the dark and analyzed by flow cytometry. Data are represented as mean (boxes) and SEM (error bars) for n=3. *Statistically significant difference from the control (p<0.05) using Dunnett's multiple comparison test.
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