Article Figures & Data
Figures
- Figure 1.
Average food intake of mice in study groups. See Materials and Methods for details.
- Figure 2.
The body weight of each mouse was recorded once a week to determine systemic toxicity. In the cisplatin-treatment groups, the mean body weight declined >18%, which suggested that i.p. cisplatin administration had toxicity.
- Figure 3.
Whole-body images of one representative mouse from each group are shown. Real-time evaluation of therapeutic interventions on colon tumor growth and metastasis was facilitated by noninvasive fluorescence imaging. Treatment efficacy on orthotopically-implanted human colon tumors was visible in live mice by GFP fluorescence. The white arrows indicate primary tumor growth.
- Figure 4.
GFP images of primary tumor in the orthotopic COLO-205 GFP mouse model from a representative mouse from each group at the time of autopsy. White arrows show the primary colon tumor. Treatment efficacy on tumor growth of orthotopically-implanted human colon tumors in each group was visible by fluorescence. No metastasis was observed in the mice in any of the cisplatin-treated groups.
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